Detailed information of ENSSYXP00000036481.1 in Micromussa lordhowensis

Genomic Location: chr11:24352520...24380374
NR annotation: XP_020626642.1, DNA ligase 1-like isoform X1 [Orbicella faveolata]
Species Micromussa lordhowensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P51892DNA ligase 1 OS=Xenopus laevis OX=8355 GN=lig1 PE=2 SV=1
P37913DNA ligase 1 OS=Mus musculus OX=10090 GN=Lig1 PE=1 SV=2
P18858DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003560 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF04679
all species →
DNA_ligase_A_CATP dependent DNA ligase C terminal region FamilyInterproscan
PF04675
all species →
DNA_ligase_A_NDNA ligase N terminusFamilyInterproscan
PF01068
all species →
DNA_ligase_A_MATP dependent DNA ligase domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000977
all species →
FamilyDNA ligase, ATP-dependentInterproscan
IPR012309
all species →
DomainDNA ligase, ATP-dependent, C-terminalInterproscan
IPR036599
all species →
Homologous_superfamilyDNA ligase, ATP-dependent, N-terminal domain superfamilyInterproscan
IPR016059
all species →
Conserved_siteDNA ligase, ATP-dependent, conserved siteInterproscan
IPR012310
all species →
DomainDNA ligase, ATP-dependent, centralInterproscan
IPR012308
all species →
DomainDNA ligase, ATP-dependent, N-terminalInterproscan
IPR050191
all species →
FamilyATP-dependent DNA ligaseInterproscan
IPR012340
all species →
Homologous_superfamilyNucleic acid-binding, OB-foldInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR45674
all species →
DNA LIGASE 1/3 FAMILY MEMBERInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003910
all species →
Molecular FunctionDNA ligase (ATP) activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0071897
all species →
Biological ProcessDNA biosynthetic processInterproscan
GO:0006281
all species →
Biological ProcessDNA repairInterproscan
GO:0006310
all species →
Biological ProcessDNA recombinationInterproscan
GO:0003677
all species →
Molecular FunctionDNA bindingInterproscan
GO:0003909
all species →
Molecular FunctionDNA ligase activityInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005739
all species →
Cellular ComponentmitochondrionInterproscan
GO:0006266
all species →
Biological ProcessDNA ligationInterproscan
GO:0006273
all species →
Biological Processlagging strand elongationInterproscan
GO:1903461
all species →
Biological ProcessOkazaki fragment processing involved in mitotic DNA replicationInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10747LIG1; DNA ligase 1EC:6.5.1.1
EC:6.5.1.6
EC:6.5.1.7
DNA repair and recombination proteinsko03400deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Micromussa lordhowensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Micromussa lordhowensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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