Genomic Location: chr2:10758085...10764843
NR annotation: XP_020602790.1, mevalonate kinase-like isoform X2 [Orbicella faveolata]
Species Micromussa lordhowensis · all data for this species · gene families
| CDS |
| ENSSYXT00000048671 |
| Transcript |
| ENSSYXT00000048671 |
| Protein |
| ENSSYXP00000046233.1 |
| UniProt accession | Description |
|---|---|
| Q5E9T8 | Mevalonate kinase OS=Bos taurus OX=9913 GN=MVK PE=2 SV=1 |
| Q9R008 | Mevalonate kinase OS=Mus musculus OX=10090 GN=Mvk PE=1 SV=1 |
| P17256 | Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004699 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08544 all species → | GHMP_kinases_C | GHMP kinases C terminal | Family | Interproscan |
| PF00288 all species → | GHMP_kinases_N | GHMP kinases N terminal domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036554 all species → | Homologous_superfamily | GHMP kinase, C-terminal domain superfamily | Interproscan |
| IPR013750 all species → | Domain | GHMP kinase, C-terminal domain | Interproscan |
| IPR006203 all species → | Conserved_site | GHMP kinase, ATP-binding, conserved site | Interproscan |
| IPR006205 all species → | Family | Mevalonate kinase | Interproscan |
| IPR006204 all species → | Domain | GHMP kinase N-terminal domain | Interproscan |
| IPR020568 all species → | Homologous_superfamily | Ribosomal protein uS5 domain 2-type superfamily | Interproscan |
| IPR014721 all species → | Homologous_superfamily | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43290 all species → | MEVALONATE KINASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0004496 all species → | Molecular Function | mevalonate kinase activity | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0006695 all species → | Biological Process | cholesterol biosynthetic process | Interproscan |
| GO:0008299 all species → | Biological Process | isoprenoid biosynthetic process | Interproscan |
| GO:0019287 all species → | Biological Process | isopentenyl diphosphate biosynthetic process, mevalonate pathway | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00869 | MVK, mvaK1; mevalonate kinase | EC:2.7.1.36 | Peroxisome | ko04146 | deepkoala |
Genes whose expression across the transcriptome samples of Micromussa lordhowensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Micromussa lordhowensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
