Genomic Location: not available for this species
NR annotation: XP_029192757.2, DNA topoisomerase I, mitochondrial-like [Acropora millepora]
Species abbreviation MEFFL · all data for this species · gene families
| CDS |
| ENSTIFT00000004934 |
| Transcript |
| ENSTIFT00000004934 |
| Protein |
| ENSTIFP00000004617.1 |
| UniProt accession | Description |
|---|---|
| Q7YR26 | DNA topoisomerase 1 OS=Chlorocebus aethiops OX=9534 GN=TOP1 PE=2 SV=1 |
| P11387 | DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 |
| Q04750 | DNA topoisomerase 1 OS=Mus musculus OX=10090 GN=Top1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005150 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02919 all species → | Topoisom_I_N | Eukaryotic DNA topoisomerase I, DNA binding fragment | Family | Interproscan |
| PF14370 all species → | Topo_C_assoc | C-terminal topoisomerase domain | Family | Interproscan |
| PF01028 all species → | Topoisom_I | Eukaryotic DNA topoisomerase I, catalytic core | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013500 all species → | Domain | DNA topoisomerase I, catalytic core, eukaryotic-type | Interproscan |
| IPR014711 all species → | Homologous_superfamily | DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type | Interproscan |
| IPR013499 all species → | Domain | DNA topoisomerase I, eukaryotic-type | Interproscan |
| IPR008336 all species → | Domain | DNA topoisomerase I, DNA binding, eukaryotic-type | Interproscan |
| IPR036202 all species → | Homologous_superfamily | DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily | Interproscan |
| IPR025834 all species → | Domain | Topoisomerase I C-terminal domain | Interproscan |
| IPR001631 all species → | Family | DNA topoisomerase I | Interproscan |
| IPR011010 all species → | Homologous_superfamily | DNA breaking-rejoining enzyme, catalytic core | Interproscan |
| IPR013034 all species → | Homologous_superfamily | DNA topoisomerase I, DNA binding, N-terminal domain 1 | Interproscan |
| IPR018521 all species → | Active_site | DNA topoisomerase I, active site | Interproscan |
| IPR013030 all species → | Homologous_superfamily | DNA topoisomerase I, DNA binding, N-terminal domain 2 | Interproscan |
| IPR014727 all species → | Homologous_superfamily | DNA topoisomerase I, catalytic core, alpha/beta subdomain | Interproscan |
| IPR048045 all species → | Domain | DNA topoisomerase I, DNA-binding domain | Interproscan |
| IPR051062 all species → | Family | DNA topoisomerase IB | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10290 all species → | DNA TOPOISOMERASE I | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0003917 all species → | Molecular Function | DNA topoisomerase type I (single strand cut, ATP-independent) activity | Interproscan |
| GO:0006265 all species → | Biological Process | DNA topological change | Interproscan |
| GO:0005694 all species → | Cellular Component | chromosome | Interproscan |
| GO:0005730 all species → | Cellular Component | nucleolus | Interproscan |
| GO:0006260 all species → | Biological Process | DNA replication | Interproscan |
| GO:0007059 all species → | Biological Process | chromosome segregation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03163 | TOP1; DNA topoisomerase I | EC:5.6.2.1 | DNA replication proteins | ko03032 | deepkoala |
