Gene detail

Detailed information of ENSTIFP00000026207.1 in Montipora efflorescens

Genomic Location: BLFP01002553.1:324513...335676
NR annotation: XP_044165080.1, cell division control protein 6 homolog isoform X1 [Acropora millepora]
Species Montipora efflorescens · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSTIFT00000028108

TCATTCACCGCTTCAACGCTTCGCTGTTGCTAGAACTTTGATTTCTGGAGATACAAAGCGATTTCCTTGCAGCTACTTGTACCAAGATGCCTAGAATAACTCGAAGCAGCCAAAGACAAATCGAGTTTCGTGTTCGCAAAACCACTCAAGACCAACGAAGAGTAAAGGGAGACACGACTAATAAAGAGGCAACGAGGATTCCTTTTGATCAAACGTGCACAACTTCACCTCGAAAGCGACGCGGTCCACCGAAAGCAGTGGAGGCAAAATGCTCAACTGTATCCCCAAAGAGGAGAAGAGACAACAGAGGCAAACAGGAAGATGCAAAATTCACTGATCCTGAAAACCTGGATCCAAAACAAAAACTATCATTTGATTGTCAAGACGCTGGAACTCCATCATCGCAACAAAAGAGACAAACCCAAGGAAAAtctaaaaaattaattgccacTGAAACACAGCGTTCAGAACCAAAACAGATTCTATCACTTGCTAGACAAgatgGACATCAATACTCAAAGGTTAGAAGAGCTCTCCACTCTTCTCACCCTGAAAACTTGCTTTGTCGAGAGAATGAGATCGCAGAAATCAGATCATTTCTTGAAAGTCATCTTCGCAAAGGAAAACCAGGTAGCTTGTACATATCTGGAGCGCCTGGAACAGGAAAAACAGCTTGTTTGACAAAGATCATGTTTGAAATGAAGGAAGAGATAAGGAAATGCCAAGTTATCTTTGTAAACTGCATGGCGTTGAAACAGCCTCAGGATATTTTCAGGAAAATTGCACTTGAGTTGGTCGGTGAAGAAAACTGTCCAGCAAAGGCCACACTTAAGTTATTAGAAGAAGAATTCTCCTCATCAAAACTCACAAGAATTTTAATCTTGGATGAATTAGATCAACTTGAGTCAAAGAATCAGGAAATTCTCTACACCATGTTTGAGTTGCCATCTCTTCCAAAATCTAAGCTCATTTTGATTGGAATAGCAAATGCTCTGGATCTTACTGACAGGATTCTTCCCAGATTACAAGCAAGGCCTAAATGTAAACCAGAACTGCTTCACTTTGCCCCATACACAAAAGACCAGATTGTGAAAATTCTACAAGACAGGCTATCAAGGGTTGAGGAAGGAATTAGTATTCTTGACACATCAGCTGTTCAGTTTTGTGCAAGGAAGGTATCAGCCATGGCTGGTGATATGAGAAAGGCTCTGGATATCTGCAgGAGAGCTGTAGAAGTTGTAGAGTCAGGAGAAAGGAAACAACAGATTTTACAGCCAATTCATACAGCTGCCTCACCGCAAAAGCGACCAGAAACACCACCAAAGCCTAAAAAGGTTGGGATTTCCCAAATTGCCAGTGTTGTAGCTGAAGTATATGGGTCGCGTCTTGTGGCTGGACCAGGAGTGGAACAACCGACAATTCCTTTGCAACAAAAACTTCTCATCTGTACATTTCTATTGATGACAAAAGATTGCAAAACTAAAGAAGTTGTTTTGGGGAAGTTCCATGATGCATACTGCAAAATTTGCAGCAGAAGGAAAGTCTCACCGCTTGGTCAAGAGGATTTTCTTGGTCTTTGCAACATCTTGGAAACAAGAGGACTTTTGGGCATCAAGAGAGCTAAAGACACAAGAATGATGAAGGTGACACTGAAAATAGATGAAAAAGAGGTTGATTATGCCCTTCAAGACAAAACCTTATTATCCAGTATACTTCAAGAAGGAATGCCTAcagctttaaaaaattaaatgtgttATTCAGCCACAAGTTATCAAGTTAGAAACAATTATGGTGATCTGGTATATGGTACATAATGTAACTTAGGGTAAAGAACAATGCctgttttctctttaaaaaaatttaagaaatgagAAGGGAATAAGAAACGaatttgaataggccatttccgagttcatgtctgcctcctcttcaaagcgagtctaagtgcaaagtttttgtgatggtaattggttctactttacatatgaatgaaaactaattttcataagaaaaacttcacacttagactcgctttgaagaggaggcaggtatgaactcgaaaatggcctattattgcCTCAAATACACAGATGTCACTCCAAACTATACTCAGCAGtcttgtttcattcattttcaAATGCCAATCATTGACCTCTGAAGTCCAATGATGCttataatattaattttcttaaaaACAATATAATTGTCTGACTTAATAGCTTGGAGGCTCTTTAACAAGGTGGTCAGGTTCAGTTTGCTTCCAAATTCAATCAAGGACTCTACTTTTAAATAGTGTTATGTTACGGTCAAAAACGGTCAAGTATTTCCCAAAGGTTTCATCCAtgcattgattttgaaaactgaaatttttcATGGTCTCTACTTACAAGttatgaaaaccaa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q99741	Cell division control protein 6 homolog OS=Homo sapiens OX=9606 GN=CDC6 PE=1 SV=1
O89033	Cell division control protein 6 homolog OS=Mus musculus OX=10090 GN=Cdc6 PE=1 SV=2
Q8W032	Cell division control protein 6 homolog B OS=Arabidopsis thaliana OX=3702 GN=CDC6B PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006924 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF09079 all species →	Cdc6_C	CDC6, C terminal winged helix domain	Domain	Interproscan
PF17872 all species →	AAA_lid_10	AAA lid domain	Domain	Interproscan
PF13401 all species →	AAA_22	AAA domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015163 all species →	Domain	Cdc6, C-terminal	Interproscan
IPR016314 all species →	Family	Cell division protein Cdc6/18	Interproscan
IPR003593 all species →	Domain	AAA+ ATPase domain	Interproscan
IPR041083 all species →	Domain	AAA lid domain	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR050311 all species →	Family	Origin Recognition Complex 1/Cell Division Control Protein 6	Interproscan
IPR036390 all species →	Homologous_superfamily	Winged helix DNA-binding domain superfamily	Interproscan
IPR049945 all species →	Domain	ORC1/DEAH AAA+ ATPase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10763 all species →	CELL DIVISION CONTROL PROTEIN 6-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006270 all species →	Biological Process	DNA replication initiation	Interproscan
GO:0051301 all species →	Biological Process	cell division	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0003688 all species →	Molecular Function	DNA replication origin binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0033314 all species →	Biological Process	mitotic DNA replication checkpoint signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K02213	CDC6; cell division control protein 6	-	DNA replication proteins	ko03032	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora efflorescens tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora efflorescens, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →