Genomic Location: BLFP01003891.1:1008337...1025426
NR annotation: XP_015763438.1, PREDICTED: insulin receptor substrate 1-B-like [Acropora digitifera]
Species Montipora efflorescens · all data for this species · gene families
| CDS |
| ENSTIFT00000036902 |
| Transcript |
| ENSTIFT00000036902 |
| Protein |
| ENSTIFP00000034295.1 |
| UniProt accession | Description |
|---|---|
| Q6P4Y6 | Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 GN=irs1 PE=2 SV=1 |
| P35569 | Insulin receptor substrate 1 OS=Mus musculus OX=10090 GN=Irs1 PE=1 SV=1 |
| P84770 | Insulin receptor substrate 1-B OS=Xenopus laevis OX=8355 GN=irs1-b PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0007645 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02174 all species → | IRS | PTB domain (IRS-1 type) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR002404 all species → | Domain | IRS-type PTB domain | Interproscan |
| IPR039011 all species → | Family | Insulin receptor substrate | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10614 all species → | INSULIN RECEPTOR SUBSTRATE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005158 all species → | Molecular Function | insulin receptor binding | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0008286 all species → | Biological Process | insulin receptor signaling pathway | Interproscan |
| GO:0043548 all species → | Molecular Function | phosphatidylinositol 3-kinase binding | Interproscan |
ENSTIFP00000034295.1.Genes whose expression across the transcriptome samples of Montipora efflorescens tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Montipora efflorescens, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |