Gene detail

Detailed information of ENSTIFP00000046319.1 in Montipora efflorescens

Genomic Location: BLFP01005029.1:308703...312666
NR annotation: XP_015761821.1, PREDICTED: rap guanine nucleotide exchange factor 1-like [Acropora digitifera]
Species Montipora efflorescens · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSTIFT00000049857

ATGGCTTCCCCGATTAAACGAATTATGAGCTTAAGGGAGACCAAAGCGAACTCTACGTCGCCACCGATGTCGCTTTCTCCTGGAAATCGAAAACCGAAATTTCTAAAAGTTCTTCGAAGGCATTCTTTCAGCCAAGGAAGGCGAAAGAGCCATGATGAGGAGGCACGAAAAGAGAGAGTGAAAGAGGTCGAAGATTTGCCGACAAAACCAGCAAGAAAATCGTCACAACAAAGCCGCGATTTGGAAGCTTTCGAACAGTATCACAAAGAACTAAAGAGCGCAGTTCACTATTTCATTTTGGTTGTTGACAAATTCCAAAACAACATGGAGATCGTGATGGCGAAGATACCAGATAACTGTTCCATAGTCTTGGAATCAGTAATAAACATAGACAATATGTTGGACACATGTCTTCGGCTCCACAGTTGGAACAACACTGAATTGGTTTCACACCGAAAAGTCATTCATAAAAAAGTCGCGGATTTAACGAGATGGTGTGATATACTATTAGTGAGAGGCAATGTGAAAGGCGATCTCATGGAAGGAGTACAGTTTGTCAAAGCACTAGAGGAAAGTGTTCAAGAACTTGTCCTTCTAGCGATCCCGCGACTTCGCAAGCAAGAACTTAATCATGAAATCAGAAATTCCATCTTCATGTTCGAGGGATCCAGTGAGAGCATACAAGTTGGGGAAGACTGTTCCGAGATTGGGCAGCCCCCATGGTCTGGTTCAAATCGGAGGGACTCTGGTATTAGTGAAGGAAGTCTTGGGGCAACTGATTCATCTAGCAGCAGGCCCTCGCCAACAACTTCACGGGATTCAGGCAGAGGGAGTTACAACTACATCCTTGATTCTGATACCTCTCATCATAATGGCCATTTGGGCCCACCTGAGCCACTAGTAAGGGGTCGGCAGTCTCACAGAAACACATCAAATTACTATCACCAAAGTCTCAATGCTAGTTCAAAGAACTCTGACTGGTCTCTCAGTCAGACGAGTGACTCATCCAGTTACAGATCCTTGCCACAATCTCCTGTTAGCTCTCATGATGAGTTCAGCGGGAATGCTTACTTCTCTGCATCAAGTTCTACAGGGGAAGAAGGATCCTTTTATTCTGCTGATGATGAAGATTCAGATCCTCCCATTATCCAAGCAAAATTTCTTGGTGCTACTGAAAACCACGAAATCTCAACACCTAAGAAGAAATCATTTCAAGTATACATTGAACTTGTTGGAAATTACACACAACCATCTGATGTCATCCTTAAGCGACCTTCATCAGCTTATGAGGGTTACCAGGAAACTTTCAGGAGAAGTATAACTACACAAACCAACTCTCCTGCACATCATACTCCTACGGCATTGAAGAAGGATATCTTTACTTTTCGAAATGTCACTGACTCAGAGCGGTCACACTCATTGCCTCTTCTCCAAAGTCCTGCAAAGGTACAGCTGAACTTTACTCAGGACTTTAATAAGAATATACAAGCGGAAGTCCCCAGGAATAAGCTTCTTCCAGTGGAGGAGGAGAGGCGCCGGAAGCAGAGTAATGCAAGCAGCAGCTCGAGCAGTTTGAGTGGAACTGAAGATGAGGATGTTAATACCCCTGCACTAGATTGCTTGGatgtttccaaatttcttgTTTATCGTCAGGATGAAGATGGACAAACATTGATTGGAGGTGCAATCGATGCGCTTATTGTCCATGCTAGTGGTTCCACCAAGAAAGACTTGGTGTATTATGAAGCATTTCTCACCACTTACAGAACATTTATCTCTCCAAAGAATCTGATTGATAAGCTCCTCTATCGAGAAAGAAGGTTCCGGGAGAAAGGTTGCAAGAAGGCAAGCCagaatgctttttttttacttttgcgaGTAGTTGATGAACTGACAGGGAAAGTTGAAAGGTGCATCTTAGAACAACTGATGAAAGAAGTCTACCGCCTTCTTGTGAATGGACACGTAGTTCTTGGAAAAATTCTTCGTGACAAGATGCTCCCTAAATGCGAGAACTACTACAGGTCACGTTCCTTATCAGGATTTGTTCATCCAGTGTTTCCTGACCCAACTCAAAAGTACACTGTGCTTGATTTCCATGCAGAAGAATTGGCTAAGCAGCTAACTTTGATTGATGCAAAGAATTTTCATAACATTGAGATTCCAGAAATTCTTGCATGGGGGAAGGAGCAAAAAGAGGAATTATCTCCAAACCTCTGTATTTTCACCGAGCATTTTAACAAGGTGTCTTATTGGTGCCGAACCCATGTTCTGTCTTTTGAGAAACAACGAGACAGAGAACTGGTCTACCTGAAATTTCTTAAGATAATGAAACATTTGCGAAGGTTTAATGACTTTAATTCTTTGTTTGGAATTCTTTCTGCACTGGACTGTTCCGCTGTCAGAAGACTGAACTGGCCAAAGCATTTGCCAGATGGTCTTGCAGAGTATGCGACACTGATTGACAGCACGTCATCTTTCAGAGCTTATCGGGATGCTCTGGCCACAGCAGAGCCACCATGCATTCCATATCTTGGGCTCATCCTTCAAGATGTCACATTTGTTTTCCATGGCAACACGGATGAACTTCCTGATGGCAAAGTGAACTTCATGAAGAGGTGGCAGTTATTTAACATTTTAGACAATGTGCGCCGATTTAAACTTACTTCTTATGACTTTGAATGGAATGATCAAATTGCACAGTTGTTTCTTGGAATGAACAATTTCTTGTCAGAGGAAGAACTGTATGAAAAGTCACTCAAGTTGAAACCTCGGGAGTAA

Transcript

ENSTIFT00000049857

GTTGAAATCACGAACCTTCTGTTGTTTACAGGCTGATTGATAACGTTTTTCAAAAGGCAACAGGATGTTTGCTGAATAATCGTGCAACCGTGAACTGTAGCGGTAAGCTATTTCTTAATTATCGTTGCGGGAAAAACAGATATTTGCCTCACGGACAATTGGTTGTGTTTTGAAATTGGTGTGGGGTTTCATACTGTGGATTCCTTGCACATGTTTAGTGTGCCGTTGGACTTTTGTTGTGTGAAACTGTAGGAGTAAACGCTTGCGAAATCCCCGTGATTCTGCTCATGTGAATTGCAATGGCTTCCCCGATTAAACGAATTATGAGCTTAAGGGAGACCAAAGCGAACTCTACGTCGCCACCGATGTCGCTTTCTCCTGGAAATCGAAAACCGAAATTTCTAAAAGTTCTTCGAAGGCATTCTTTCAGCCAAGGAAGGCGAAAGAGCCATGATGAGGAGGCACGAAAAGAGAGAGTGAAAGAGGTCGAAGATTTGCCGACAAAACCAGCAAGAAAATCGTCACAACAAAGCCGCGATTTGGAAGCTTTCGAACAGTATCACAAAGAACTAAAGAGCGCAGTTCACTATTTCATTTTGGTTGTTGACAAATTCCAAAACAACATGGAGATCGTGATGGCGAAGATACCAGATAACTGTTCCATAGTCTTGGAATCAGTAATAAACATAGACAATATGTTGGACACATGTCTTCGGCTCCACAGTTGGAACAACACTGAATTGGTTTCACACCGAAAAGTCATTCATAAAAAAGTCGCGGATTTAACGAGATGGTGTGATATACTATTAGTGAGAGGCAATGTGAAAGGCGATCTCATGGAAGGAGTACAGTTTGTCAAAGCACTAGAGGAAAGTGTTCAAGAACTTGTCCTTCTAGCGATCCCGCGACTTCGCAAGCAAGAACTTAATCATGAAATCAGAAATTCCATCTTCATGTTCGAGGGATCCAGTGAGAGCATACAAGTTGGGGAAGACTGTTCCGAGATTGGGCAGCCCCCATGGTCTGGTTCAAATCGGAGGGACTCTGGTATTAGTGAAGGAAGTCTTGGGGCAACTGATTCATCTAGCAGCAGGCCCTCGCCAACAACTTCACGGGATTCAGGCAGAGGGAGTTACAACTACATCCTTGATTCTGATACCTCTCATCATAATGGCCATTTGGGCCCACCTGAGCCACTAGTAAGGGGTCGGCAGTCTCACAGAAACACATCAAATTACTATCACCAAAGTCTCAATGCTAGTTCAAAGAACTCTGACTGGTCTCTCAGTCAGACGAGTGACTCATCCAGTTACAGATCCTTGCCACAATCTCCTGTTAGCTCTCATGATGAGTTCAGCGGGAATGCTTACTTCTCTGCATCAAGTTCTACAGGGGAAGAAGGATCCTTTTATTCTGCTGATGATGAAGATTCAGATCCTCCCATTATCCAAGCAAAATTTCTTGGTGCTACTGAAAACCACGAAATCTCAACACCTAAGAAGAAATCATTTCAAGTATACATTGAACTTGTTGGAAATTACACACAACCATCTGATGTCATCCTTAAGCGACCTTCATCAGCTTATGAGGGTTACCAGGAAACTTTCAGGAGAAGTATAACTACACAAACCAACTCTCCTGCACATCATACTCCTACGGCATTGAAGAAGGATATCTTTACTTTTCGAAATGTCACTGACTCAGAGCGGTCACACTCATTGCCTCTTCTCCAAAGTCCTGCAAAGGTACAGCTGAACTTTACTCAGGACTTTAATAAGAATATACAAGCGGAAGTCCCCAGGAATAAGCTTCTTCCAGTGGAGGAGGAGAGGCGCCGGAAGCAGAGTAATGCAAGCAGCAGCTCGAGCAGTTTGAGTGGAACTGAAGATGAGGATGTTAATACCCCTGCACTAGATTGCTTGGatgtttccaaatttcttgTTTATCGTCAGGATGAAGATGGACAAACATTGATTGGAGGTGCAATCGATGCGCTTATTGTCCATGCTAGTGGTTCCACCAAGAAAGACTTGGTGTATTATGAAGCATTTCTCACCACTTACAGAACATTTATCTCTCCAAAGAATCTGATTGATAAGCTCCTCTATCGAGAAAGAAGGTTCCGGGAGAAAGGTTGCAAGAAGGCAAGCCagaatgctttttttttacttttgcgaGTAGTTGATGAACTGACAGGGAAAGTTGAAAGGTGCATCTTAGAACAACTGATGAAAGAAGTCTACCGCCTTCTTGTGAATGGACACGTAGTTCTTGGAAAAATTCTTCGTGACAAGATGCTCCCTAAATGCGAGAACTACTACAGGTCACGTTCCTTATCAGGATTTGTTCATCCAGTGTTTCCTGACCCAACTCAAAAGTACACTGTGCTTGATTTCCATGCAGAAGAATTGGCTAAGCAGCTAACTTTGATTGATGCAAAGAATTTTCATAACATTGAGATTCCAGAAATTCTTGCATGGGGGAAGGAGCAAAAAGAGGAATTATCTCCAAACCTCTGTATTTTCACCGAGCATTTTAACAAGGTGTCTTATTGGTGCCGAACCCATGTTCTGTCTTTTGAGAAACAACGAGACAGAGAACTGGTCTACCTGAAATTTCTTAAGATAATGAAACATTTGCGAAGGTTTAATGACTTTAATTCTTTGTTTGGAATTCTTTCTGCACTGGACTGTTCCGCTGTCAGAAGACTGAACTGGCCAAAGCATTTGCCAGATGGTCTTGCAGAGTATGCGACACTGATTGACAGCACGTCATCTTTCAGAGCTTATCGGGATGCTCTGGCCACAGCAGAGCCACCATGCATTCCATATCTTGGGCTCATCCTTCAAGATGTCACATTTGTTTTCCATGGCAACACGGATGAACTTCCTGATGGCAAAGTGAACTTCATGAAGAGGTGGCAGTTATTTAACATTTTAGACAATGTGCGCCGATTTAAACTTACTTCTTATGACTTTGAATGGAATGATCAAATTGCACAGTTGTTTCTTGGAATGAACAATTTCTTGTCAGAGGAAGAACTGTATGAAAAGTCACTCAAGTTGAAACCTCGGGAGTAAAAAGTTTAATCAGTTGGTAAAACAAGTTTCATTCAGATTCTAAATTTGAACAATGGCTCAGTAAAAAAGTAATGCAGACATTTTCGTGTTCATTGGCCTTTCACACTTTCTTTAAGTGTATTTCAGTTTGTCTGATATTTTTGTATTCAATTCATGACAAATTTTTTGGATATCTTTGGTTGAGATTAAGAAAAAGAGACAGAATAGAATCAAACAGATTAACTATACTGTAAAATCAAATACATTTTTATATTCTGGTACAGGTTGTAGGAGTCATTTTATTCTGCTTAATTTTGTAGTACGGTTAACCTATTTTTGTACAAAACAGTTATGCAAGACTATTGTAGGTCACTTTGTACCTTTTGTAAAGGCAAGATACCAGTTCAGCACAAATTTATTGTGGGTATAGTGTTGTAtggaaaaagttaattttttcacgGTTAGAGGACTAGGATGTGACCATTTTTAGGGGCATGCTCTTTATGTAAAATAAATCACATCTTTCCATCAAATACTTCATTTCCTATCACTTGATATATCTTATCCCCTTCCCTTGCATATAAAGTATTTCGACACAGTGACATCAGTATGTTAGAGTTACAATATTCTTGCAGTTGATGTATTGATTCTTTTAATTCATGATACATTAATAGTTGCTCTTTGGCTTTCCTATTTTGTGACAAATGTCTTGAGGATTAGAACATGTTGAAACAGAATTTTAAGTGGCTtgacaaattacatttttgaaaaacgattttgtgtaaataataaatttttaatcaCTCTAGGCTTGaaggttttatttttaaaaaagatgatACTTTTGCAGGTAATATTAAAGGTGGACACAGTGACTTAAATAGAATTACTGTACTTGTTTTCAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q13905	Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3
O77086	Guanine nucleotide-releasing factor 2 OS=Drosophila melanogaster OX=7227 GN=C3G PE=1 SV=4
Q8IS14	Ras guanine nucleotide exchange factor J OS=Dictyostelium discoideum OX=44689 GN=gefJ PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007728 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00618 all species →	RasGEF_N	RasGEF N-terminal motif	Domain	Interproscan
PF00617 all species →	RasGEF	RasGEF domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001895 all species →	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR023578 all species →	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan
IPR000651 all species →	Domain	Ras-like guanine nucleotide exchange factor, N-terminal	Interproscan
IPR008937 all species →	Family	Ras-like guanine nucleotide exchange factor	Interproscan
IPR036964 all species →	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan
IPR019804 all species →	Conserved_site	Ras guanine-nucleotide exchange factor, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23113 all species →	GUANINE NUCLEOTIDE EXCHANGE FACTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0007264 all species →	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007265 all species →	Biological Process	Ras protein signal transduction	Interproscan
GO:0043547 all species →	Biological Process	positive regulation of GTPase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K06277	RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1	-	Renal cell carcinoma	ko05211	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora efflorescens tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora efflorescens, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →