Gene detail

Detailed information of ENSTIFP00000048618.1 in Montipora efflorescens

Genomic Location: BLFP01004894.1:147265...149427
NR annotation: XP_015779619.1, PREDICTED: ski oncogene-like [Acropora digitifera]
Species Montipora efflorescens · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSTIFT00000052334

ATGGAGCGGCGTAAATTCTCGCGTTCAGACAACCCCCTCATAGACGAGATCCTTCAAAAATACCGCGATTGTTCAACAGAGTCCATGACGGGGCCTAAAGGCTTGACCGCGAATCGAGCTACCGCAAAGAAACCGTGGAGTTCTACAGACGACTTTGCCAAACACAGCTATGTTTCGTCTAGCGATCATGCTCGAGCTGCGATAAACAAGACATTTACAGTGAGAATACCACCACCGAAGGGACAAGATAGTTTCACATTCAAGGAGACTATCATCGACGGTGTTCCTTTGGCCTGCTTCAGCTCGGGCGGAGAGAAGCGAGTTTGTTACACCGAACTTGTGAACAAAGTCCTAAAGGATTTTGAGAATAAGGAGATAGACGCAAACCGCGATCGCCTTCAAATTTGCTGTCCCCGCTGCTCGTCGCAACAATTAGAACTCTTTAAGCTAGCTGGCGTTTTACCTTGGTCGTCAGCCTCGGCCAGTTTCATCTCCAAGACGGATTCTTTTCGTTTGATCGGTGTCTTGACCGCGAGTGAGGTCCCCCGGAGATCGAGTCGTATTTTTCCCGTAGACAGTTTGGAAGTGTACCATGAATGTTTTGGCGGATGTGTCGGCACTTTAGAAATCGACAAGTATACTGATCCGTACGCAAAATGTATAACCTGCTCTCATTGCGATGGAATATTTTCGCCGCGCAGATTCGTGATTCACAATCACTCCTCCGGCGAAATTCATACCTGTCACTGGGGCTTCGACGATGCGAAATGGAGGCTTTATTTGATGCTTTGCAACGAGCAACCTACTTTGCACGTGCAGAAACTTTGGGAAATGCTGTTAAATAAATTCTCAGACGGACAGCGGTGCAAACGAGCTTCGCCGGCAAGCGATCATGACGCAGACGGGAACGAGCGCGACAGTGGCGCGAGCACTCCAAAAAAAGCACGCGTGGACGACTCGCAAGAGCAACGCGAGAGTGACAACGATGTAGGAAACGGGAATAGCAGCGGTAACAGTTCTAATGGGGATATTATGTGTCGGAGGTCTGCGTTCCGGCCTTGGTCGCCTCTGCATGGACGTATTAAGGCTAATGAAACCTCAACATCGACTCAAGGTTTGTTAGCTACAAGTTCTCCTGCGAGACTGTTTTCTCCTCACACTATCCCGTATCTCGCGAGCGATAGCCCTTACAACCCACCCCCTCACCCTTCGTCTTTTCACCCGAGCTCCGCCAATGTGTCTCACACAGTCAGTGAAATTCTGGCAACTCCGTCCACTAAAGATCCCAGATCGCTTGAAAAAACGGCTAAAGAAATGCTAGAAGTTGTTGCACAGAACGAAAGATGGACCGGCTACGATACCGGTAACAAGCGAAGTCCTCCTAGAAGAAACCTGAGCGAGGAAAAAGAAGACAACGACAGCGCGCTTCTGGAGGAGGAGATTTACGGCAAACTGGCCAGCTTAACAAGCAAGAGAGATTACGATAAGATGCCCTCGCCCAGGGAATTGAGTAGCTTATTAGCTAAAGAAATCAAGGATTTGTTTAGCAAGCACGCGGAGGACAAAGTAAAAGAGCTGGCCGAAATGAAGAATAAATTGCGCTCGGAACTGGAATCATTACAGCGCGAGCACACCAAGAAAATGGAAGAAGCCTTGCAAGAACTCAAAAGCGTTCAAAAAGAAGCGAGAATGCTGCAAACGAGCCACAGGCTTGAAATGGAAACCTTAAACGAAAAGAATATCAAACTCCAACTCGAAATTAAGCGATATAAAGCCGAAAAGGAAGGTATTTTACCTATGAACTCTAAAGAAACCCTCACCGTCTTACAGCAAGATGTCAGAGACCTTTCAAAAAAGTTAgaagaaaaagatatttactgtagagaacttgaaaatgaaattcaagGGTTTCATTCTTGGATTAACAGTCAGAGATTACGTAATACAAACTCACAGTTTGTGTACGCAGTTAATAGTGGACTAAGACGTGATCCAGAATCGGTGATCAGAACGGGTAATATTGCAAATGGAAATTTATATGAACGCAAAGTTACTGTCAGCAAGTCCAATGGCTCGACTCACAGTGAAAGCTCGGGGGACGAATAA

Transcript

ENSTIFT00000052334

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P17863	Transforming protein Ski OS=Avian erythroblastosis virus (strain Sloan-Kettering) OX=11862 GN=V-SKI PE=1 SV=1
P49140	Ski oncogene OS=Gallus gallus OX=9031 GN=SKI PE=1 SV=1
Q02225	Ski oncogene OS=Xenopus laevis OX=8355 GN=ski PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0008501 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08782 all species →	c-SKI_SMAD_bind	c-SKI Smad4 binding domain	Domain	Interproscan
PF02437 all species →	Ski_Sno	SKI/SNO/DAC family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR014890 all species →	Domain	c-SKI SMAD4-binding domain	Interproscan
IPR003380 all species →	Domain	SKI/SNO/DAC domain	Interproscan
IPR037000 all species →	Homologous_superfamily	Ski-like, DNA-binding domain superfamily	Interproscan
IPR010919 all species →	Homologous_superfamily	SAND-like domain superfamily	Interproscan
IPR009061 all species →	Homologous_superfamily	Putative DNA-binding domain superfamily	Interproscan
IPR023216 all species →	Family	Transcription regulator SKI/SnoN	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10005 all species →	SKI ONCOGENE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0046332 all species →	Molecular Function	SMAD binding	Interproscan
GO:0000978 all species →	Molecular Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Interproscan
GO:0000981 all species →	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0030514 all species →	Biological Process	negative regulation of BMP signaling pathway	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K26503	SKI; Ski oncogene	-	TGF-beta signaling pathway	ko04350	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora efflorescens tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora efflorescens, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →