Gene detail

Detailed information of ENSVBPP00000001567.1 in Meandrina meandrites

Genomic Location: chr11:9071699...9081328
NR annotation: XP_020614474.1, rasGAP-activating-like protein 1 isoform X1 [Orbicella faveolata]
Species Meandrina meandrites · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSVBPT00000001722

AGCACAGCCTTCCTGGCGAAGCTCAAACCCAGTCAAAGCAGGGACGCCTGGTACAAGTTGCTCCCGATGCCTCACATCAAAGAACATAAAACTGAAAATCTGGGCAGTATCCGAATGAAGGTTCGTTTGACACAGGAACGCATCCTACCCCAGAAATGTTACCAGTCGCTGGTAGACATTCTTGTTAACTCCACCAAGGACCCAGAGAACCTGGACCCCACTGCGCTGAGCTTAATAGAACAGCTGAACGCCGCTGACCAGGCAATATTGGCTCACCAGTTGGTTAGACTGTTTATTGGCCAGGACGTGGTTATACCATTTCTGGATTATCTCACACTTCGAGAGATAAGAGAATCAAGTAATCCAAGGACACTGTTTAGGGGCAACAGTCTGGCAGCAAAATGCATGGAACAATTCATGAAGATTGTGGGTATGCCATACCTTTCAGACACATTAAAGCCAGTCATAGATAAGATTTTCGAAGAACGGAAATACTGCGAGCTGGATCCGAGTAAAAACGCGGAGCGCAAACACAGCGCTCTCAGACGTCTGAGTCTAAGGCCAGTTGATGAACAGGACAGAAGCCTGTCAGTTATGACTGGTTACTTGGAGATCGTCATGACTTCAATCTTAAGTTCAATCAAGGAATGTCCAACATACATGCGCGCAGCCTTCAGAAATCTCGCTCGGCGAGTCTCCGATCACTTTGGAGAAGAACCTGGATGCGAGGATTCCAAATACACAGCTGTGAGTGGCTTCCTGTTTCTCCGGTTCTTCGCGCCCGCAATTCTCGGACCCAAGCTCTTTGGTTTGAGGGAAAACCACGCGGACAAGAATGTCTCCCGCACACTAACCATCTTGGCAAAGACGGTCCAGAAGATTGGCAACATTGAGCTGCCACTACACAACGGGAAAGAAGAGTGGATGGGACCGCTGTACAGGTGGATCGCATTCTACACAGACGAAGTGAAGGACTTTTTGGACAGGCTCGCTGACGTAGAAGACGAAGAAGTCCCAGGCTGTGACCACAGGAGGACCGTGTTCAGTCACTCGCTGATTATCAAGGAGGGTCCCGTTAAGAAATGTCGCTACAGGGATACCAGGCTACCCAAACCATATAAGTTTAAAAAACGCTACTGTTGGCTAAGCACAGAAAATTTCCTTTACGCTAAAACAAATGATTCGCAGACAAGGCAGTTTCTTCCAACAAGGAAAATCCTGGCAGTAGAACGAGTCGATGAGTCAGCATTTCAAAAGCCAAACGTGTTTCAGGTGGTCAGCAAAGATTATGATGACGCTCTGCAAATCCTTTACCTTGCTGCTCAGGATGTGAATGAAATGAATCAGTGGCTGTCAGCGATTAGGAAGACGACCATTTCCAATCCAAAAATGCTACCTTTCTTCCATCCGGGAGTCTTTCACAAAAACAAATGGACGTGCTGCAAACGCGTGATAAAAACAGCTCGAGGATGCCACTTGACACATACGCACGTGACCTTGAGTGACTGGCGTGACCCACTCGACCCAGACTCTGAAGCACAGATGATTTTCACCCAGCTGCTTCAAAGTCGCGATGAGCtgcaaaaaaaattcctggaaacAACAGAACCTCAAAAGAATTCTCTAGATTCTGACACGGATAAAGACGAACAGACACCTGAAAAGAACGTTCAAGCATCTTCAACAGCCAGTGAGAAAGCCATGGCAACGAAACTATTAGAAGTAATTGACGAACTAGAGAAAGCCCACAAAACCTTTGAGGAAAAGGCGATTACAAAATTATAGAATTATATATAAGACAAAATTAAAGATTGTGCAGAGAGAATATTTTCAAATATGAATGATTGCAAAGAATTTTAGTTAAGGTGATGCAAATTTTGAAATAAGTTTTTTACAAATTAGAactggttgggggggggggggggtacttcctCTAGTGGACAatacggggaggctccaccCAAAGGGGTACATTTATTAAGCTGGAAATACACAAGGGTGGGGATTTCACGAGTTGTAGTACagaaaaaagaaggaaaaacagtCATTTAGTTATATAAAAGGTCTTTTAACTGAACAGCTCCACCAAACAGTTGATTCATGTATTTTAAGGGGTTATTCAAGCGCAAAAAATTAGAACATAGAAGCAGTATTCCTACTGTAGTTATGTGAAGGGGTTTCTATTTGCTATCAAAGATATATAAAAGGGTTaccttttttgtcaaaaatggtatatgaaaggggaaaggggaaaggggtaagggtttgccccccccccccccccctcccttccatataaaatatttttgagtACACCACTGGGGCAAACTAGTTTCTTTAGCACCAAGAGCCTTGCAAAGGAGATACTTCCAAATATGAGCCATACGGGTATGTACAACTGGCACCCTAGTCTCTTGGCATTCTTTCTTGTTTCGATGACCACGCAAAGGCTGGGTGTctgg

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O95294	RasGAP-activating-like protein 1 OS=Homo sapiens OX=9606 GN=RASAL1 PE=1 SV=3
Q9Z268	RasGAP-activating-like protein 1 OS=Mus musculus OX=10090 GN=Rasal1 PE=1 SV=2
Q6PFQ7	Ras GTPase-activating protein 4 OS=Mus musculus OX=10090 GN=Rasa4 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006928 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00779 all species →	BTK	BTK motif	Motif	Interproscan
PF00169 all species →	PH	PH domain	Domain	Interproscan
PF00616 all species →	RasGAP	GTPase-activator protein for Ras-like GTPase	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001562 all species →	Conserved_site	Zinc finger, Btk motif	Interproscan
IPR008936 all species →	Homologous_superfamily	Rho GTPase activation protein	Interproscan
IPR039360 all species →	Family	Ras GTPase-activating protein	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR023152 all species →	Conserved_site	Ras GTPase-activating protein, conserved site	Interproscan
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR001936 all species →	Domain	Ras GTPase-activating domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10194 all species →	RAS GTPASE-ACTIVATING PROTEINS	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0043087 all species →	Biological Process	regulation of GTPase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSVBPP00000001567.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Meandrina meandrites tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Meandrina meandrites, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →