Gene detail

Detailed information of ENSVBPP00000012342.1 in Meandrina meandrites

Genomic Location: chr7:30471013...30483535
NR annotation: XP_020604387.1, transcription factor IIIB 90 kDa subunit-like [Orbicella faveolata]
Species Meandrina meandrites · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

ENSVBPT00000012867

GAGACTCGTATCGCCGGCTCTGTCTGCCATTTTTGTTCTCTTTGGCTAATACCTCGCAGGGAGGGTGGAAAAAAATCAGCAGCATGTCACAGGTTTGTTCGAATTGTGGTGGAAGTGATATTGACACTGATCAAGCCCGTGGCGATGCAGTTTGTATGGGATGTGGGTCCGTACTTGAAGACAACATTATCATCTCAGAAGTTCAGTTTCAAGAAAATAGCATTGGAGGGGCTAGTGCTATTGGACAGTTCGTCTCAGCCGAAGGAAACAAGGCAGGAGTTAGTTTAGGATCTGCATTTCGTCATGGGCTTGGCCAGGAATCAAGAGCAGTCACTCTTGAAAATGGGAAGAGAAGAATCAATACTGTAGGCCACCAGTTGCAGATGAATCAGCATTGTATCGACACAGCTTACAACTTCTACAAGCTGGCAGTCAACAAGCGTCTCACCAGGGGCAGGCGAACAAATCATGTTGTGGCAGCATGCCTGTACCTTGTGTGCAGAACAGAGAAAACCCCTCACATGCTGCTGGACTTCAGTGATGTTTTACAGATTGATGTTTTCACTCTTGGTAGAGCATACCTGAAGCTGGCTCAAGAACTTTACATCAACTTACCTGCAGTTGATCCCTGCCTGTACATCCATCGTTTTGCACACAAGTTACAATTTGGTGAAAAGGAGCATGATGTTGCCATGACAGCCTTAAGGCTTGTAGCAAGAATGAAGAGAGACTGGATTCATCATGGCCGAAGACCTTCAGGCCTCTGTGGAGCAGCTCTTTTAGTTGCTGCAAGGTTACATGGATTTAACAGAACAGTGCGTGAAGTTGTCAAAACTGTTCGCATCAGTGACACTACTATAAGAAAGAGGTTGGGTGACTTCCGTGACACGCCGTCCAGTCAGCTAACCATTGACGAATTTCAAACAATTGATCTTGAGGAGGAGCAGGACCCTCCATCATTCACACAGGCAAGAAGAAGGGCAAAACAACAACTCGAGGAGCTGAACAAACCAGAAATTGCTTCAGAATTAGAAGCATTTCAGAACTCAATTGAGAACATTTTGGGCATTGATTCCACAAAGGACAAACCTGTCACAGCAGAGGAAAATGGACATGCTGATGACTTAAACAGGACTTCTGAAAAGGATGTTACAAGGGATGTTCATAGTGGCCCTGCACTTGTAGTTCCTCCTCTTGGCACAGCAGATCACGGCAGATCTGACAAAAATGACAACATACATGTAGAAgATAAAACAGAAGAAGATAAAGAAAGTGAAGAGTTGGATCTAACAGGCCTGGATGATACAGAACTTGAtaaaTGTCTCTTAAACGAAACTGAGATAGcaatcaaaacaaaactgtGGATGGAAGAAAACAAAGaatatttacaaaaacaaaaagAAAAAGAGGAAAAGGAAGCGCGAGAGAGAGAAGAAGGCAATAAACAGGAACCAAAAAAGAAAAGAAAACCATACAAGAAAAGGGTGGCAACCGGACCAGCGAGCACTGCTGGCGAGGCCATAGAAAAGATGCTTGTAGAAAAGAAAATATCCAGTAAAATAAACTATGAGGTGCTTAGAGGTCTGGAGACAAGTCAATCTAGCAAACCGGCTGCACCAGTCATACCCGTTTCTGAACCGGTTTTACCGCTCAAACAGGAATTTATAACTCCGCGTGTACCAACGAGGACAGGAGGACGAAAGCGAGAGTCTTCTACTCCTGTTGCATCGCCTTCGGACACCTTCAAGAAACCAAAGCTTGCTCAGTCCCAGAAGCCAGTTAAGGTGGAAGGAGTTGACAAAGAAGTTGTCATTGAAAGCGGCCCCGTAGAGTATGAAAAGACCGACGGATCTAACCCCGTGGGGGAGGAGGACGAATTTGACGAACTGGAAGAGGAGGACGAAGAACCAGTAAGCGCGGTGCATCTCATGGGTCATTTATATGACGCAAATCTTGAAGACGAATATGGTGACTTTGAAGATTACGAGTAACAATTCTGTCAACCGCTGCACCTATTGTGATTCTCCAATCCTTTTTCAGCCACGTTTAGTGGAACAGAGTGCCTTTTGGCATATCCTGGAAAAAATTACATCTGATTCTGAAGAGTTTCCACTGTCTCCAGTCAATTTGGAAATGTCGCGAGCATTCATGAGGACACCAAAAGTTGCACGTAAGCTGGACACCATAAAGTTACGTCATGTTACTTAGCAACCAAAGTGACGTTAACGGTGGGCTCAAAAAAACTTGCGCAGCCAGCGGTTTACGCCAGAGAGAAGACAAAATTCCGGGTGTAATCACTGTGGATAAGTTCTtcaggaaaattaaaattattattattattttttagctaTTTTACGATGAAGGGCACGATCTATTGTGTGAAGTTAAACAGGTATTGGAAATGATTACTGTCGAAGGTGAACTTTGGTTAAAAAAGCAAGTAGAATAGAGCAATCATGCAAGATTTGAAGAAACTCAAACTTTTTGTGAACGTCTGTGAAGTGGTACACCCACAATGTGAACAACTTTCCACCAAAGTGGTACCGCTAGAAAAGCCACTTCTCCAAGAAATGGACACTCTTTAAATTGGACAGCTCACAAATGGACACCCCTCTGAAGTGGGACATTCCCTTGGGCAACTACCTCCCTAAAACGGACACATTGGGCTGGTTCTTTGCCATATTGCAGTCCTTTATTTTGTGTACCCAAAATATAGAAAACGTTTCCGTATGACTAGGAAGTCAGTGCTTATTTTTCAAGACTGAAAAATATCGTGGTAAATTGGAAGCGTGCAGGTGAAGCAGTACCCTCAGACACACCTCTACAAGGCGGACACGTGACCTTTCAATGGTGGACAGTATTGCACTGTACTAATAACATTTAAAACAGCCTTGAAGAATATGCATTCTTTTTAATATCGATTACTCTTGCCTTTCAATAATATTGACAT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q92994	Transcription factor IIIB 90 kDa subunit OS=Homo sapiens OX=9606 GN=BRF1 PE=1 SV=1
Q8CFK2	Transcription factor IIIB 90 kDa subunit OS=Mus musculus OX=10090 GN=Brf1 PE=1 SV=1
Q9P6R0	Transcription factor IIIB 60 kDa subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=brf1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003241 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08271 all species →	TF_Zn_Ribbon	TFIIB zinc-binding	Domain	Interproscan
PF07741 all species →	BRF1	Brf1-like TBP-binding domain	Domain	Interproscan
PF00382 all species →	TFIIB	Transcription factor TFIIB repeat	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR013763 all species →	Domain	Cyclin-like domain	Interproscan
IPR013137 all species →	Domain	Zinc finger, TFIIB-type	Interproscan
IPR011665 all species →	Domain	Brf1, TBP-binding domain	Interproscan
IPR000812 all species →	Family	Transcription factor TFIIB	Interproscan
IPR013150 all species →	Domain	Transcription factor TFIIB, cyclin-like domain	Interproscan
IPR036915 all species →	Homologous_superfamily	Cyclin-like superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11618 all species →	TRANSCRIPTION INITIATION FACTOR IIB-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006352 all species →	Biological Process	DNA-templated transcription initiation	Interproscan
GO:0070897 all species →	Biological Process	transcription preinitiation complex assembly	Interproscan
GO:0017025 all species →	Molecular Function	TBP-class protein binding	Interproscan
GO:0000126 all species →	Cellular Component	transcription factor TFIIIB complex	Interproscan
GO:0000995 all species →	Molecular Function	RNA polymerase III general transcription initiation factor activity	Interproscan
GO:0001006 all species →	Molecular Function	RNA polymerase III type 3 promoter sequence-specific DNA binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006383 all species →	Biological Process	transcription by RNA polymerase III	Interproscan
GO:0097550 all species →	Cellular Component	transcription preinitiation complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K15196	BRF1, GTF3B; transcription factor IIIB 90 kDa subunit	-	Transcription machinery	ko03021	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Meandrina meandrites tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Meandrina meandrites, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →