Genomic Location: chr5:37044260...37051559
NR annotation: XP_020622933.1, serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like [Orbicella faveolata]
Species Meandrina meandrites · all data for this species · gene families
| CDS |
| ENSVBPT00000032265 |
| Transcript |
| ENSVBPT00000032265 |
| Protein |
| ENSVBPP00000030987.1 |
| UniProt accession | Description |
|---|---|
| P48454 | Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform OS=Homo sapiens OX=9606 GN=PPP3CC PE=1 SV=3 |
| P63328 | Protein phosphatase 3 catalytic subunit alpha OS=Mus musculus OX=10090 GN=Ppp3ca PE=1 SV=1 |
| P63329 | Protein phosphatase 3 catalytic subunit alpha OS=Rattus norvegicus OX=10116 GN=Ppp3ca PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000472 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00149 all species → | Metallophos | Calcineurin-like phosphoesterase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR041751 all species → | Domain | PP2B, metallophosphatase domain | Interproscan |
| IPR043360 all species → | Family | PP2B | Interproscan |
| IPR006186 all species → | Domain | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase | Interproscan |
| IPR004843 all species → | Domain | Calcineurin-like phosphoesterase domain, ApaH type | Interproscan |
| IPR029052 all species → | Homologous_superfamily | Metallo-dependent phosphatase-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45673 all species → | SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005516 all species → | Molecular Function | calmodulin binding | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0005955 all species → | Cellular Component | calcineurin complex | Interproscan |
| GO:0033192 all species → | Molecular Function | calmodulin-dependent protein phosphatase activity | Interproscan |
| GO:0097720 all species → | Biological Process | calcineurin-mediated signaling | Interproscan |
| GO:0016787 all species → | Molecular Function | hydrolase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K04348 | PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit | EC:3.1.3.16 | Protein phosphatases and associated proteins | ko01009 | deepkoala |
Genes whose expression across the transcriptome samples of Meandrina meandrites tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Meandrina meandrites, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
