Gene detail

Detailed information of ENSVBPP00000032297.1 in Meandrina meandrites

Genomic Location: chr3:10482027...10495805
NR annotation: KAJ7385579.1, Metal transporter cnnm2 [Desmophyllum pertusum]
Species Meandrina meandrites · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

ENSVBPT00000033647

ATGCGACGCCTCATTTTTGTCGTCCAATCACCGGCACCAAAGAAACGGTATTCTTTCGTGAACATGAAACTGACAGGAATAAGTCCAGTTGGTAATTCAGGTGGCAAATCATCCATCGAGGATGGTATTGTCCTGATAACTGCCGACAATTTAGTGTCGCTCCGATTCTACGGAGCGGGGTTTTCGCGGGATACTCGTATTGCCTTTACAACAACCGCGggaaaattgaagacgaaatgCGAAGCTGATCGAACAAAGCCTATAAAGTTTAAAGAGGATGGCTTACAAGAATATAAAGGAGAAGCAGAAGTTAGCTTATCAGCTACGAGTGACGGGCAACCGTATTTTATCTGCTTGCAATCCGGTAATGGCAGCGCATGGTTGCATCAAGGTGCAAGTGACACACTTCTCCAAATTAAGACAACCAGCAAAAGCGGTTTGCCCCTTTGGCTAAAGATAGTATTCATTGTGATTCTCATGACTCTGTCAGGCTTGTTTTCAGGGCTAAATCTGGGGCTAATGGCGCTAGATCCGACAGAGCTTAAAATCGTCATGAACTGCGGCAATCCCAGTGAGCAGCAATACGCGAAAAGCATCGATCCACTTCGCAGACATGGCAATTATCTACTGTGTACGCTACTGCTGGGCAATGTTTTGGTGAATACTTCGTTTACAGTGCTTTTAGACGGCATAATCGGCGACGGAATCGCGGCGGTTCTTGGTTCAACCGCCGGTATCGTGATCTTCGGCGAGATAATACCCCAAAGTATTTGTTCCAGACATGGTTTGGCCGTCGGTGCTCGTACCATCTGGATCACAAGGTTTTTCATGCTAGTAACGTTTCCTGTATCTTTCCCAATAAGTAGGATCTTGGATTGGATATTAGGTAACGAGATTGGCACAGTGTATAATAGGAAACAGCTACAGGAAATGTTGAGAGTTACAGCTGAGTTCAATGATTTGGAAGGAGATGAAATGAACATCATTTCAGGGGTATTGAACTATAAGAGCAAAACAGTCGAAGAAGTCATGACCAAACTAGAGGATTGCTACCTCCTCGACTTGTCATCCATTCTTGATTTTAGAACTATTGCGCATATCATGCAATCGGGGCATAGTCGCATTCCAGTATACGATGGTGAGCGGCATAACATAGTGGGTCTGCTGCTGGTAAAGGATTTGGCCTTTATTGATACCGATGACTGCACCCCTTTGCGCACAGTTATTAAGTTTTACAATCACCAGGTCCAGCGTGTTTTTGATGACGTCCATCTGGATGCAATGCTTGAGGAGTTTAAAAAGGGGCATTCGCACTTGGCGGTGGTGCAGCGGGTCAACAGTGAAGGCGATGGAGATCCCTTCTACGAAGCTATTGGTATCGTCACTTTAGAGGACATCTTGGAGGAAATAATTCAGTCAGAAATTGTTGATGAAACCGACATCTATTTGGATAACAAGTCGGGACAAGTCATACCTGGACGCAAGGGACTAATGAAAGACCTTTCGTTATTTTCTGAAGAGCAAGACAAGCCAAAGGTATCACCTCAGTTGCAGCTGGCAATATTGCAGTATCTTGCCAcagctGTTGATGCATTCAGTGAGGACATTATCTCTCTCAATGTACTCAAGCGATTAATTGACCAACCTCACGTTGTccaagaaatcaaaattcaagatGAGGATGACATGAAGCACAAATATCTGTACAAGAAAGGTGTCGCAGGAGAATTCTTCACACTGATCATTCAGGGCAAGGTGGAAGTCACCATCGGACAAGAAGAGCTTAGCTTTGAGGAAGGCCCATTTACATTCTTTGGCACAAAAGCACTGGTGTCGTCACTGAGCACGAGTAACCCTAACGTGCGAGCAGTGGGTCAGTATGTCCCAGACTACTCTGTGCGCGTCATCACTGACCTCATGTACCTGAAGATATCCAAGGGAATATACAGACAGGCTGTGCGTGCCACTTTGATGGAACGTCAGCAGGGAACGGATGGAATCGACGGAATGATTCCAGGGCTGGGACGGATGATTGCCGGGATGAATCATGTCAATGGGCTTGGAATTCAGTCTGATCATGTTTATTTGGAAACCACTTGTTATGTTAATGCTTTACTGATTCGCACTTTAAAATCCTGTGGTTGCTTTGAATTGAATTTTAATATCGGGCAGAAGGGACCCTCGTGGATCATCACCTTGCGTACGAATCCCAGGTCTCGAGCGTTCCATGCGGGAATTTATCTGACTCGTGTGCGAGGGTTTCTCTTATTGCCCAATGAACaaggagtctgggaacgagttcTGGAAATGAACCGTTTTTGTGTCACAAGTTATTAG

Transcript

ENSVBPT00000033647

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6P4Q7	Metal transporter CNNM4 OS=Homo sapiens OX=9606 GN=CNNM4 PE=1 SV=3
Q5U2P1	Metal transporter CNNM2 OS=Rattus norvegicus OX=10116 GN=Cnnm2 PE=2 SV=1
Q3TWN3	Metal transporter CNNM2 OS=Mus musculus OX=10090 GN=Cnnm2 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001895 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00571 all species →	CBS	CBS domain	Domain	Interproscan
PF01595 all species →	CNNM	Cyclin M transmembrane N-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000644 all species →	Domain	CBS domain	Interproscan
IPR018490 all species →	Homologous_superfamily	Cyclic nucleotide-binding domain superfamily	Interproscan
IPR000595 all species →	Domain	Cyclic nucleotide-binding domain	Interproscan
IPR044751 all species →	Domain	Ion transporter-like, CBS domain	Interproscan
IPR046342 all species →	Homologous_superfamily	CBS domain superfamily	Interproscan
IPR002550 all species →	Domain	CNNM, transmembrane domain	Interproscan
IPR045095 all species →	Family	Ancient conserved domain protein family	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12064 all species →	METAL TRANSPORTER CNNM	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006810 all species →	Biological Process	transport	Interproscan
GO:0010960 all species →	Biological Process	magnesium ion homeostasis	Interproscan
GO:0022857 all species →	Molecular Function	transmembrane transporter activity	Interproscan
GO:0030026 all species →	Biological Process	intracellular manganese ion homeostasis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for ENSVBPP00000032297.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Meandrina meandrites tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Meandrina meandrites, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →