Genomic Location: chr13:22113481...22177902
NR annotation: PFX14964.1, Spectrin alpha chain [Stylophora pistillata]
Species Meandrina meandrites · all data for this species · gene families
| CDS |
| ENSVBPT00000038634 |
| Transcript |
| ENSVBPT00000038634 |
| Protein |
| ENSVBPP00000037031.1 |
| UniProt accession | Description |
|---|---|
| Q9NRC6 | Spectrin beta chain, non-erythrocytic 5 OS=Homo sapiens OX=9606 GN=SPTBN5 PE=1 SV=2 |
| Q00963 | Spectrin beta chain OS=Drosophila melanogaster OX=7227 GN=beta-Spec PE=1 SV=2 |
| Q01082 | Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001340 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00307 all species → | CH | Calponin homology (CH) domain | Domain | Interproscan |
| PF08031 all species → | BBE | Berberine and berberine like | Domain | Interproscan |
| PF15410 all species → | PH_9 | Pleckstrin homology domain | Domain | Interproscan |
| PF00435 all species → | Spectrin | Spectrin repeat | Domain | Interproscan |
| PF01565 all species → | FAD_binding_4 | FAD binding domain | Domain | Interproscan |
| PF00498 all species → | FHA | FHA domain | Family | Interproscan |
| PF13325 all species → | MCRS_N | N-terminal region of micro-spherule protein | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001715 all species → | Domain | Calponin homology domain | Interproscan |
| IPR012951 all species → | Domain | Berberine/berberine-like | Interproscan |
| IPR018159 all species → | Repeat | Spectrin/alpha-actinin | Interproscan |
| IPR036872 all species → | Homologous_superfamily | CH domain superfamily | Interproscan |
| IPR000253 all species → | Domain | Forkhead-associated (FHA) domain | Interproscan |
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| IPR016169 all species → | Homologous_superfamily | FAD-binding, type PCMH, subdomain 2 | Interproscan |
| IPR036318 all species → | Homologous_superfamily | FAD-binding, type PCMH-like superfamily | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR006093 all species → | Binding_site | Oxygen oxidoreductase covalent FAD-binding site | Interproscan |
| IPR041681 all species → | Domain | Pleckstrin homology domain 9 | Interproscan |
| IPR036028 all species → | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR001589 all species → | Conserved_site | Actinin-type actin-binding domain, conserved site | Interproscan |
| IPR002017 all species → | Repeat | Spectrin repeat | Interproscan |
| IPR016166 all species → | Domain | FAD-binding domain, PCMH-type | Interproscan |
| IPR008984 all species → | Homologous_superfamily | SMAD/FHA domain superfamily | Interproscan |
| IPR001605 all species → | Domain | Pleckstrin homology domain, spectrin-type | Interproscan |
| IPR006094 all species → | Domain | FAD linked oxidase, N-terminal | Interproscan |
| IPR025999 all species → | Domain | Microspherule protein, N-terminal domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11915 all species → | SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0050660 all species → | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0030036 all species → | Biological Process | actin cytoskeleton organization | Interproscan |
| GO:0030054 all species → | Cellular Component | cell junction | Interproscan |
| GO:0030864 all species → | Cellular Component | cortical actin cytoskeleton | Interproscan |
| GO:0042995 all species → | Cellular Component | cell projection | Interproscan |
| GO:0051015 all species → | Molecular Function | actin filament binding | Interproscan |
| GO:0071949 all species → | Molecular Function | FAD binding | Interproscan |
| GO:0005543 all species → | Molecular Function | phospholipid binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06115 | SPTBN1_4_5; spectrin beta, non-erythrocytic 1/4/5 | - | Cytoskeleton proteins | ko04812 | deepkoala |
Genes whose expression across the transcriptome samples of Meandrina meandrites tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Meandrina meandrites, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |