Genomic Location: chr6:4395486...4403331
NR annotation: XP_027057350.1, beta-secretase 2-like [Pocillopora damicornis]
Species Meandrina meandrites · all data for this species · gene families
| CDS |
| ENSVBPT00000043313 |
| Transcript |
| ENSVBPT00000043313 |
| Protein |
| ENSVBPP00000041445.1 |
| UniProt accession | Description |
|---|---|
| W8W138 | Beta-secretase OS=Strongylocentrotus purpuratus OX=7668 GN=BACE PE=2 SV=1 |
| Q9Y5Z0 | Beta-secretase 2 OS=Homo sapiens OX=9606 GN=BACE2 PE=1 SV=1 |
| Q2HJ40 | Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004324 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00026 all species → | Asp | Eukaryotic aspartyl protease | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR033121 all species → | Domain | Peptidase family A1 domain | Interproscan |
| IPR021109 all species → | Homologous_superfamily | Aspartic peptidase domain superfamily | Interproscan |
| IPR001461 all species → | Family | Aspartic peptidase A1 family | Interproscan |
| IPR001969 all species → | Active_site | Aspartic peptidase, active site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR47965 all species → | ASPARTYL PROTEASE-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004190 all species → | Molecular Function | aspartic-type endopeptidase activity | Interproscan |
| GO:0005768 all species → | Cellular Component | endosome | Interproscan |
| GO:0005802 all species → | Cellular Component | trans-Golgi network | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0006509 all species → | Biological Process | membrane protein ectodomain proteolysis | Interproscan |
| GO:0050435 all species → | Biological Process | amyloid-beta metabolic process | Interproscan |
ENSVBPP00000041445.1.Genes whose expression across the transcriptome samples of Meandrina meandrites tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Meandrina meandrites, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |