Detailed information of ENSXFYP00000045009.1 in Duncanopsammia axifuga

Genomic Location: chr7:26725203...26731554
NR annotation: XP_020618880.1, glycine receptor subunit alpha-4-like isoform X2 [Orbicella faveolata]
Species Duncanopsammia axifuga · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P07727Glycine receptor subunit alpha-1 OS=Rattus norvegicus OX=10116 GN=Glra1 PE=1 SV=4
P57695Glycine receptor subunit alpha-1 OS=Bos taurus OX=9913 GN=GLRA1 PE=1 SV=1
P23415Glycine receptor subunit alpha-1 OS=Homo sapiens OX=9606 GN=GLRA1 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000070 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02931
all species →
Neur_chan_LBDNeurotransmitter-gated ion-channel ligand binding domainFamilyInterproscan
PF02932
all species →
Neur_chan_membNeurotransmitter-gated ion-channel transmembrane regionFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR006201
all species →
FamilyNeurotransmitter-gated ion-channelInterproscan
IPR036734
all species →
Homologous_superfamilyNeurotransmitter-gated ion-channel ligand-binding domain superfamilyInterproscan
IPR036719
all species →
Homologous_superfamilyNeurotransmitter-gated ion-channel transmembrane domain superfamilyInterproscan
IPR018000
all species →
Conserved_siteNeurotransmitter-gated ion-channel, conserved siteInterproscan
IPR006028
all species →
FamilyGamma-aminobutyric acid A receptor/Glycine receptor alphaInterproscan
IPR038050
all species →
Homologous_superfamilyNeuronal acetylcholine receptorInterproscan
IPR002289
all species →
FamilyGamma-aminobutyric-acid A receptor, beta subunitInterproscan
IPR006202
all species →
DomainNeurotransmitter-gated ion-channel ligand-binding domainInterproscan
IPR006029
all species →
DomainNeurotransmitter-gated ion-channel transmembrane domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR18945
all species →
NEUROTRANSMITTER GATED ION CHANNELInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004888
all species →
Molecular Functiontransmembrane signaling receptor activityInterproscan
GO:0005216
all species →
Molecular Functionmonoatomic ion channel activityInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0034220
all species →
Biological Processmonoatomic ion transmembrane transportInterproscan
GO:0005230
all species →
Molecular Functionextracellular ligand-gated monoatomic ion channel activityInterproscan
GO:0006811
all species →
Biological Processmonoatomic ion transportInterproscan
GO:0004890
all species →
Molecular FunctionGABA-A receptor activityInterproscan
GO:0005231
all species →
Molecular Functionexcitatory extracellular ligand-gated monoatomic ion channel activityInterproscan
GO:0005254
all species →
Molecular Functionchloride channel activityInterproscan
GO:0005887
all species →
Cellular Componentplasma membraneInterproscan
GO:0007165
all species →
Biological Processsignal transductionInterproscan
GO:0007268
all species →
Biological Processchemical synaptic transmissionInterproscan
GO:0030594
all species →
Molecular Functionneurotransmitter receptor activityInterproscan
GO:0042391
all species →
Biological Processregulation of membrane potentialInterproscan
GO:0043005
all species →
Cellular Componentneuron projectionInterproscan
GO:0045202
all species →
Cellular ComponentsynapseInterproscan
GO:0050877
all species →
Biological Processnervous system processInterproscan
GO:1902476
all species →
Biological Processchloride transmembrane transportInterproscan
GO:1904315
all species →
Molecular Functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potentialInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
No KEGG orthology assignment for ENSXFYP00000045009.1.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Duncanopsammia axifuga tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Duncanopsammia axifuga, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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