Genomic Location: chr7:26725203...26731554
NR annotation: XP_020618880.1, glycine receptor subunit alpha-4-like isoform X2 [Orbicella faveolata]
Species Duncanopsammia axifuga · all data for this species · gene families
| CDS |
| ENSXFYT00000050152 |
| Transcript |
| ENSXFYT00000050152 |
| Protein |
| ENSXFYP00000045009.1 |
| UniProt accession | Description |
|---|---|
| P07727 | Glycine receptor subunit alpha-1 OS=Rattus norvegicus OX=10116 GN=Glra1 PE=1 SV=4 |
| P57695 | Glycine receptor subunit alpha-1 OS=Bos taurus OX=9913 GN=GLRA1 PE=1 SV=1 |
| P23415 | Glycine receptor subunit alpha-1 OS=Homo sapiens OX=9606 GN=GLRA1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000070 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02931 all species → | Neur_chan_LBD | Neurotransmitter-gated ion-channel ligand binding domain | Family | Interproscan |
| PF02932 all species → | Neur_chan_memb | Neurotransmitter-gated ion-channel transmembrane region | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006201 all species → | Family | Neurotransmitter-gated ion-channel | Interproscan |
| IPR036734 all species → | Homologous_superfamily | Neurotransmitter-gated ion-channel ligand-binding domain superfamily | Interproscan |
| IPR036719 all species → | Homologous_superfamily | Neurotransmitter-gated ion-channel transmembrane domain superfamily | Interproscan |
| IPR018000 all species → | Conserved_site | Neurotransmitter-gated ion-channel, conserved site | Interproscan |
| IPR006028 all species → | Family | Gamma-aminobutyric acid A receptor/Glycine receptor alpha | Interproscan |
| IPR038050 all species → | Homologous_superfamily | Neuronal acetylcholine receptor | Interproscan |
| IPR002289 all species → | Family | Gamma-aminobutyric-acid A receptor, beta subunit | Interproscan |
| IPR006202 all species → | Domain | Neurotransmitter-gated ion-channel ligand-binding domain | Interproscan |
| IPR006029 all species → | Domain | Neurotransmitter-gated ion-channel transmembrane domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR18945 all species → | NEUROTRANSMITTER GATED ION CHANNEL | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004888 all species → | Molecular Function | transmembrane signaling receptor activity | Interproscan |
| GO:0005216 all species → | Molecular Function | monoatomic ion channel activity | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0034220 all species → | Biological Process | monoatomic ion transmembrane transport | Interproscan |
| GO:0005230 all species → | Molecular Function | extracellular ligand-gated monoatomic ion channel activity | Interproscan |
| GO:0006811 all species → | Biological Process | monoatomic ion transport | Interproscan |
| GO:0004890 all species → | Molecular Function | GABA-A receptor activity | Interproscan |
| GO:0005231 all species → | Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | Interproscan |
| GO:0005254 all species → | Molecular Function | chloride channel activity | Interproscan |
| GO:0005887 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0007268 all species → | Biological Process | chemical synaptic transmission | Interproscan |
| GO:0030594 all species → | Molecular Function | neurotransmitter receptor activity | Interproscan |
| GO:0042391 all species → | Biological Process | regulation of membrane potential | Interproscan |
| GO:0043005 all species → | Cellular Component | neuron projection | Interproscan |
| GO:0045202 all species → | Cellular Component | synapse | Interproscan |
| GO:0050877 all species → | Biological Process | nervous system process | Interproscan |
| GO:1902476 all species → | Biological Process | chloride transmembrane transport | Interproscan |
| GO:1904315 all species → | Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Interproscan |
ENSXFYP00000045009.1.Genes whose expression across the transcriptome samples of Duncanopsammia axifuga tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Duncanopsammia axifuga, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |