Genomic Location: :...
NR annotation: XP_002160090.1, cytoplasmic protein NCK2 [Hydra vulgaris]
| CDS | |||||
| ENSXLYT00000004745 | |||||
| Transcript |
| ENSXLYT00000004745 |
| Protein |
| ENSXLYP00000004569.1 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| P16333 | SH2/SH3 adapter protein NCK1 OS=Homo sapiens OX=9606 GN=NCK1 PE=1 SV=1 | ||||
| Q99M51 | SH2/SH3 adapter protein Nck1 OS=Mus musculus OX=10090 GN=Nck1 PE=1 SV=1 | ||||
| O43639 | Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00018 | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00017 | SH2 | SH2 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR036860 | Homologous_superfamily | SH2 domain superfamily | Interproscan |
| IPR000980 | Domain | SH2 domain | Interproscan |
| IPR051184 | Family | Tyrosine-phosphorylated adapter molecule | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR19969 | SH2-SH3 ADAPTOR PROTEIN-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0016477 | Biological Process | cell migration | Interproscan |
| GO:0030971 | Molecular Function | receptor tyrosine kinase binding | Interproscan |
| GO:0035591 | Molecular Function | signaling adaptor activity | Interproscan |
| GO:0036493 | Biological Process | positive regulation of translation in response to endoplasmic reticulum stress | Interproscan |
| GO:1902237 | Biological Process | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | Interproscan |
| GO:1903898 | Biological Process | negative regulation of PERK-mediated unfolded protein response | Interproscan |
| GO:1903912 | Biological Process | negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K19862 | NCK2, GRB4; NCK adaptor protein 2 | - | Pathogenic Escherichia coli infection | ko05130 | deepkoala |