Gene detail

Detailed information of ENSXLYP00000007629.1 in Pelagia noctiluca

Genomic Location: :...
NR annotation: XP_048580364.1, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [Nematostella vectensis]

Gene Structure

More details in Jbrowse

Sequence

CDS

ENSXLYT00000007968

ATGGAAAAAAATGCAACTGCTTCAACATTAATGCCTCAGCAAGTTCGTGCGTATCTGCTGGAAAACCCCGAATTCGCAGAGGAGTATTTCATCTTCAACGCGACGGCACCTATGATTCAACGCTGGTTCGACCAGAGAAATCAGGGTAGCTGTCAGAACGGACATGCCAATCGAAGGTCGAGTCTCGACATCTCCTTACCACAGCACGTATTACACGAAGAGGAGAGCCTTGACGAGTGTCTTGAGCCGTCGTCTGTCGAGCACTTAGGCCCTCGGCGATATTCAGAGCCCGTCGCTTCATCTATAACCGAGAAGAAAGCTGCGTTCAAACTCCGTGATATGCGCAAAAAGAAAGCACTAACGCAGCACCGTATGCGTTGTAATGTGTCATCAGACTTGCCGTTCTCTTTCGCATACGAGTCCAGCAAGCAGATAGAATTTAACAAGCCGTCACTGAGAAAGACCCAGTCTGCACCCATCTACAAAAGCATGTTGTCTCGGCTGATCAATTCAACGGTTTACATACGCAGCTTTCCTAGTCAAGACACGAGATCAAAACTGGACTTAAGATCGTCTAGCGAGGATGCCTTTTTAACTGAAATCATTCACGACGTTATGAGAGACTTGAATTTGAAATCGTTGTGTCACAAAGTGATTGTCAATGTCGGTATAATAACCGATGCGGAGGTGGCTTCCTTGTATCTTATTGAGAATGTTGGCCAGAAGAAAATGCTGAGGGTTCTTTACGAGAATCTGTCTGTTTTGTCGTCTTGTGATAGTCGTGAAATGGCTGGTGGCTCTGGAAATACCCTTAAAGGTATCCAGGACGATGTTATTGGGAAAGTTGCTAAAACTGGAAAAACGGTACAAGCAAAGATTTTGGCTGAGGTATGTTGGCCAAACATCTCACAAGATTTGGTGGTAAAGTCACATGAACGAGAAATTCTTTGTAAACCTATCAAAAGCCTCAATGGAGATGCCTTATCATTGTTCCAGGTTCTTGAGAGGTACCTCACGTTTTGTGGCATCAGCATCAACAATGCCCGGCTCTTCAACGTCTCCAAAGAAGAATTCGATCGAAATAAGGCATTGCTTGAGCTGGCCCATGGAATATTCGAAGAACAGACCTCGCTGAATAACATCGTAAATCAGACACTTCGGAGAGCAATCGAGTTGTTTTCGTGCAAGCAATGTGTTATAATGCTCATCGCAGACGAAAAACATACAAATTTGATTTCAGCCGAGGTTAGTTCACCTCCTTACACTTTCTACATCATGCCAGTGAAAAATGGAACTGACGAAGAGCCATGCCTGTGTATACCCTTCAGAGATAACCAGTTCCAGATAATTGGTGATGGTCTTGGTATAAGCAACTGTATTTTGTATGATGAAGTATGCCGTGCCAAGGTCCATCAGAAGGTTGCTCTTGAGGTATTAATCGGCATGAGAATTTCGATGATGAATAAGTGTTTGAATTCTATCTCGCAGCTTTCTTCGGTACCAACTGCTAAAGTGTTGCATCTCTACGATTTACGATTCGACGATTTCCAACTCATCGATGGCCAGATGTTAACTGCAGGCATCAGGATGTTTGTTGAATTCGATTTCTTCAAAACCTATCAAATCAAATACGAGACATTTTGCAGATGGCTCCTAACAGTGAAAAAAAACTACCGTCGTGTGATTTATCACAACTGGAGACACGCCTTCAACGTGGCTCAGTCGATGTTTGCAGTTCTCACGaCTGGAAAGCTGAGTGAAAAGTTCTCGAGTCTAGAATGCCTGGCTTTACTGGTCGGTTGTTTATGTCACGACCTTGATCACAGAGGGACTAACAATGACTTCCAGACAAAGAGTGAGTCTCCATTGGGAAAACTCTATGGAACATCGCCCCTGGAACATCATCACTTCAACCATGCGGTCGCCATTTTGAATAGCGAGGGGAACAATATCTTTCAAAGCCTGTCATCTACTGATTTCAAGGAAACGATGAAATACTTGAAACATGCCATTCTCGCCACAGATTTAGCGCAATACTTCAAGATTCGGGGTACTCTCTTTCCTCTCATCGAGAGTCAGCAGCTCGACGTCACTAGGAGAGATCACAAGAATATGCTCAGAGGAATGTTGATGACGGCGTGTGACCTGAGCGGGATAACAAAACCATGGGACATTCAGAAAAAGGTTGTGCATCTTGTGACGAGCGAGTTCTTTCATCAAGGAGACATAGAAAGAGAAAAATTGCAAGTTGAACCAATGGCAATTATGGACAGAAAACACATCCTTCAACTTCCTAAATTACAAGTCCAATTTTTCAACTCAACTTGCATCCCAGTATACAAGGTAaCACTGGGAGCATTCGCAGAAGGAGCTTTATCCAACAGAGCGCAGTGGGAAAAACTTAGTAAGAAAATCGATGAAGGTACGATAGACCCTGAGCTTGATCCTGTTTTTAAAACtgttagttatgatgaagatATTACATATTTATAG

Transcript

ENSXLYT00000007968

Protein

Uniprot

Uniprot term	Description
B4LVU6	cGMP-specific 3',5'-cyclic phosphodiesterase OS=Drosophila virilis OX=7244 GN=Pde6 PE=3 SV=1
Q298P4	cGMP-specific 3',5'-cyclic phosphodiesterase OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=Pde6 PE=3 SV=3
B4PSS5	cGMP-specific 3',5'-cyclic phosphodiesterase OS=Drosophila yakuba OX=7245 GN=Pde6 PE=3 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00233	PDEase_I	3'5'-cyclic nucleotide phosphodiesterase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR023088	Family	3'5'-cyclic nucleotide phosphodiesterase	Interproscan
IPR002073	Domain	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	Interproscan
IPR003607	Domain	HD/PDEase domain	Interproscan
IPR029016	Homologous_superfamily	GAF-like domain superfamily	Interproscan
IPR036971	Homologous_superfamily	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	Interproscan
IPR023174	Conserved_site	3'5'-cyclic nucleotide phosphodiesterase, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11347	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0008081	Molecular Function	phosphoric diester hydrolase activity	Interproscan
GO:0004114	Molecular Function	3',5'-cyclic-nucleotide phosphodiesterase activity	Interproscan
GO:0007165	Biological Process	signal transduction	Interproscan
GO:0004118	Molecular Function	3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	Interproscan
GO:0010754	Biological Process	negative regulation of cGMP-mediated signaling	Interproscan
GO:0043951	Biological Process	negative regulation of cAMP-mediated signaling	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K13298	PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11	EC:3.1.4.17 EC:3.1.4.35	Cushing syndrome	ko04934	deepkoala