Gene detail

Detailed information of EVM0003795.1 in Myxobolus honghuensis

Genomic Location: Contig01072:1127721...1138149
NR annotation: KII73419.1, Crossover junction endonuclease MUS81 [Thelohanellus kitauei]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q7SXA9	Structure-specific endonuclease subunit MUS81 OS=Danio rerio OX=7955 GN=mus81 PE=1 SV=1
Q640B4	Structure-specific endonuclease subunit MUS81 OS=Xenopus tropicalis OX=8364 GN=mus81 PE=2 SV=1
Q91ZJ0	Structure-specific endonuclease subunit MUS81 OS=Mus musculus OX=10090 GN=Mus81 PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02732	ERCC4	ERCC4 domain	Domain	Interproscan
PF21136	MUS81-like_WH	Crossover junction endonuclease MUS81-like, winged helix domain	Domain	Interproscan
PF21292	EME1-MUS81_C	EME1/MUS81, C-terminal	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR027421	Homologous_superfamily	DNA polymerase lambda lyase domain superfamily	Interproscan
IPR036388	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR018247	Binding_site	EF-Hand 1, calcium-binding site	Interproscan
IPR047416	Domain	MUS81, XPF-like nuclease domain	Interproscan
IPR011335	Homologous_superfamily	Restriction endonuclease type II-like	Interproscan
IPR006166	Domain	ERCC4 domain	Interproscan
IPR042530	Homologous_superfamily	EME1/EME2, C-terminal domain	Interproscan
IPR047417	Domain	MUS81, winged helix domain	Interproscan
IPR033309	Family	Crossover junction endonuclease Mus81	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13451	CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0003677	Molecular Function	DNA binding	Interproscan
GO:0004518	Molecular Function	nuclease activity	Interproscan
GO:0000712	Biological Process	resolution of meiotic recombination intermediates	Interproscan
GO:0000727	Biological Process	double-strand break repair via break-induced replication	Interproscan
GO:0005634	Cellular Component	nucleus	Interproscan
GO:0006302	Biological Process	double-strand break repair	Interproscan
GO:0006308	Biological Process	DNA catabolic process	Interproscan
GO:0008821	Molecular Function	crossover junction DNA endonuclease activity	Interproscan
GO:0031573	Biological Process	mitotic intra-S DNA damage checkpoint signaling	Interproscan
GO:0048257	Molecular Function	3'-flap endonuclease activity	Interproscan
GO:0048476	Cellular Component	Holliday junction resolvase complex	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K08991	MUS81; crossover junction endonuclease MUS81	EC:3.1.22.-	DNA repair and recombination proteins	ko03400	deepkoala