Gene detail

Detailed information of FUN_004017-T1 in Acropora pulchra

Genomic Location: ntLink_8:18129546...18162659
NR annotation: XP_044168903.1, dihydropyrimidine dehydrogenase [NADP(+)]-like [Acropora millepora]
Species abbreviation APULC · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

FUN_004017-T1

ATGGCGTTGTCAAAGGATTCGCCTGATATTGAGAACTTGCTGGCACTAAATCCCAAAATCAAGCCACATGCAAACTTGGTGTCAACATCAGCAACCAAATTAAACAGGAGGCACTGGAAGAGAAACCAAGAAAAGGGTTGCTCTAGCTGTGAAAGTTTGACAAATAACTTTGATGATGTCAAGCACTCAACATTGAGTGAAAGAGCAGCTCTCAGGGAAGCCTCGAGGTGCTTAAAGTGTGCTGATGCTCCATGCCAGAAGAGCTGTCCAACACAGTTAGACATCAAGTCCTTTATTACCAGCATTGCAAACAGGAACTATTATGGAGCTGCCAAGGCAATTTTCAGTGATAACCCACTGGGTTTGTCTTGTGGCATGGTGTGCCCTACCAGTGACCTTTGTGTTGGTGGTTGTAACCTGTATGCCTCAGAGGAGGGACCTATTAACATTGGTGGCTTGCAACAGTTTGCAACAGAGGTCTTCAAGAGCATGAAAATAAATCAAATACGTGATCCCTCTTTACCGACGACTGACCAACTTCCTGAGAGCTACCACACAAAGGTGGCACTTATTGGGTGTGGTCCAGCATCGATTAGTTGTGCAACATTTCTTGCTCGCCTGGGTTACACAAACTTGACCATATTTGAAAGGGAAAATTATATTGGTGGATTAAGTTCATCTGAAATCCCACAGTACAGACTTCCATTTGATGCTGTCAATTTTGAAGTGGAATTAATGAAGGATCTTGGTGTCAAGATTGAACTTGGCCAAGGTTTAGGTGTGAATGGTCGGTCAATCCAGTCACTTAAAGAGGAAGGATATGAAAGCATTTTCATCGGTATCGGTCTACCTGAGCCCAAGTTGTCTCCTATTTTTGATGGCTTAGGCACTGAAAATGGTTTTTATTCTTCAAAAGCCTTCTTGCCAATTGTATCAATGGGCAGTAAAGCTGGAATGTGTTCATGCAAATCCAAGTTACCTGAGCTATTTGGAAATGTCATTGTCCTTGGGTGTGGAGATACAGCTTTTGATTGCTGCACTTCATCTCTTCGGTGTGGAGCTCGTAAAGTGTTTGTTATCTTTAGAAAAGGCTTCACCAACATAAGGGCAGTCCCAGAGGAGATGCAGCTTGCAGTTGACGAGAAGTGCGAGTTCTTGCCTTTTCTTTCACCAAAGAAGGTTCTTGTCAGGGAGGGAAAGATTTGGGCCATGGAATTCTACAAGACAGAACAGTTAGAGGATGGCTCATGGATTGAGGATAAGGAACAAACATTCAAGATAAAAGCCAACTTTGTTATTTCTGCCTTTGGTTCCACGCTGACCGACAGAGATGTTGTCAAGGCCTTGGAGCCCATGAAGTTCAACAAGTGGGGTCTGCCCGAAGTTGATCCATTTTCCATGAGCACGAGCGAAGCTGGAGTCTTTTGTGGGGGAGATGTGGCTGGTGTTGCCAACACTACCGTAGAGAGTACAAACGATGGCAAACAAGCTGCATGGCATATGCACGCGTATTTACAGGCCCTGTATGGTCTGCCAGTGGTCAAAGAACCCAGTCTTCCAAAATTTTACACCGAAGTAGACAATGTGGACCTAAGTGTGGAGATTTGTGGCTTAAGAATTGATAATCCTTTTGGCCTGGCAAGTGCCCCACCCACCACCAGTGCTGCTATGATACGACGTGGCTTTGAAGCAGGCTGGGGATTTGCTGTCACCAAAACATATTCACTTGACAAGGATGCCATAACAAATGTGTCACCTCGTATCGTTCGTGGTACCACTTCTGGCCCCTTGTATGGCCCAGGCCAAGGTGCTTTTCTCAACATAGAGCTGATCAGTGAGAAGACCGCAGCTTACTGGTGCCGATCAGTTACAGAACTGAAAATGGATTTCCCACACAAGGTGTTGATTGCCAGTATTATGTGTGGTTATTCAAAGGAAGATTGGACTGAACTTGCACAGATGTCTGAGAAAGCAGGCGCAGATGCTTTAGAGCTGAACTTGTCTTGTCCGCATGGCATGGGGGAGAGAGGCATGGGACTAGCTTGTGGTCAGGATGCTGAATTGGTGCGGAACATTTGCCGCTGGGTGCGTGCTGCCGTTAAAATTCCGTTTTTTGCCAAGTTAACGCCAAACGTTACAGACATTGTGGACATTGCAAGAGCAGCTCAGGAAGGTTGTGCTGACGGAGTCACAGCGACCAATACAGTCTCTGGTTTGATGGGATTATACCCAAACAGCAGTGCATGGCCTTCTGTGGGCAAGGAAAAAAAGACCACTTATGGGGGTGTGTCTGGCAATGCGATTCGTCCAATTGCATTGCGAGCAGTGTCTGCAATTGCCAAAGCTCTGCCGGGTTTTCCCATCCTGGCTACAGGTGGAGCAGACAGTGCTGAAGCAGTGTTGCAGTTTCTTCATTGCGGTGCCTCTGCAGTCCAGATATCAAGTGCCGTGCAGAACCAGGACTTCACTCTGATTGACGATTACACTTCAGGACTCAAATGCTTGTTGTATCTTCAAACCGTTCGTGAGTTTTCTGAGTGGACTGGACAGAGTCCACCGACGCCAAAACACCAGAAAGGAAAACGTGTTCCGAGAATAGCTGAACTTGTTGGAAAGTCTCTTCCCAATTTTGGACCGTACGCGAGAGAAAGGGAAAAAATTGTGGCAAAGCACAAGGAGGAGATTGACTTGTTGAGTAGAGAGTTCGAACCAGAGGTAGTCAGACCGGCCTACAAACCTGACAAACCAGTTCCACCGGTCAAGGATATCATTGGAGCAGCGCTGGATCGCATTGGTGCTTATGGTGACCTTGACAACAAGCAGCAAGTGGTGGCGCTTATTGACGAAGACTTGTGCATTAACTGCGGCAAATGCTACATGACGTGCAATGACTGTGGTTACCAGGCCATCACGTTTGACCCCCAAACTCATTTGCCGCACGTGACGAAGGATTGCACGGGATGCACGCTTTGCGTGTCAGTCTGCCCCGTGATTGACTGTATCAAAATGGTGCCAAGGGAAGGACCTTACAAACCAAGCCGCGGTGTTCCTCTAGCAGTTAGAAGCTAA

Transcript

FUN_004017-T1

TGGTCTTTTCACGGTGGAACTGTTTGACTTGATACCAAATTAAAGTTAAGTGTTTATTGCATCTACGCGGCAATAATCTTTTATTCGTTTTTTATTTATGGTCCGTGGTTTAATCGAGATCCACGAGAGTCTTGGACAATCTCAAAATTCTTCCTCTTTTTTTCTCTTTTTTACCAGGCTAGTTTCAAGACGAGAGAAAAGTTTTAAAAAAGTTACTATGCCTTATACATTGGAATGTCGTTTTTATGAGGCTCGTGTTCGTGAAACCCACTTTTCTATGCACGACGCTCCGTGATCTTTGAACTCGGACTTAAGCGTGTTTTCGCCAGACAAGCGGTGAATTTTATTATTTTCTTTTATTTTAATTGAACCAAAACTAGTTGACATTAACCCACTCTTGGTTGTATAGAACTGCATTTTTGTGTTATTTAATTCATAGTTAAATAAAAGTTAGTAAAGATTTTGAAACAATCTGGAGTGAAGGGCCCGTTTCTCGAAAGGCCCGAAAAATTGAAATATATAATGAAGTTTTCTTGCCTCGACACCCCTTCTTTTTGAAATAGGTCACACGAAATGCGCCCGAAAAGTGTCGGGACGAGAAACGGGCCTCTGAGGCCCGGGGCGAACTTAGTCACGTGGCGGTATTGAGTTAATCCTTGCTCAAAAGTCATGGCGTTGTCAAAGGATTCGCCTGATATTGAGAACTTGCTGGCACTAAATCCCAAAATCAAGCCACATGCAAACTTGGTGTCAACATCAGCAACCAAATTAAACAGGAGGCACTGGAAGAGAAACCAAGAAAAGGGTTGCTCTAGCTGTGAAAGTTTGACAAATAACTTTGATGATGTCAAGCACTCAACATTGAGTGAAAGAGCAGCTCTCAGGGAAGCCTCGAGGTGCTTAAAGTGTGCTGATGCTCCATGCCAGAAGAGCTGTCCAACACAGTTAGACATCAAGTCCTTTATTACCAGCATTGCAAACAGGAACTATTATGGAGCTGCCAAGGCAATTTTCAGTGATAACCCACTGGGTTTGTCTTGTGGCATGGTGTGCCCTACCAGTGACCTTTGTGTTGGTGGTTGTAACCTGTATGCCTCAGAGGAGGGACCTATTAACATTGGTGGCTTGCAACAGTTTGCAACAGAGGTCTTCAAGAGCATGAAAATAAATCAAATACGTGATCCCTCTTTACCGACGACTGACCAACTTCCTGAGAGCTACCACACAAAGGTGGCACTTATTGGGTGTGGTCCAGCATCGATTAGTTGTGCAACATTTCTTGCTCGCCTGGGTTACACAAACTTGACCATATTTGAAAGGGAAAATTATATTGGTGGATTAAGTTCATCTGAAATCCCACAGTACAGACTTCCATTTGATGCTGTCAATTTTGAAGTGGAATTAATGAAGGATCTTGGTGTCAAGATTGAACTTGGCCAAGGTTTAGGTGTGAATGGTCGGTCAATCCAGTCACTTAAAGAGGAAGGATATGAAAGCATTTTCATCGGTATCGGTCTACCTGAGCCCAAGTTGTCTCCTATTTTTGATGGCTTAGGCACTGAAAATGGTTTTTATTCTTCAAAAGCCTTCTTGCCAATTGTATCAATGGGCAGTAAAGCTGGAATGTGTTCATGCAAATCCAAGTTACCTGAGCTATTTGGAAATGTCATTGTCCTTGGGTGTGGAGATACAGCTTTTGATTGCTGCACTTCATCTCTTCGGTGTGGAGCTCGTAAAGTGTTTGTTATCTTTAGAAAAGGCTTCACCAACATAAGGGCAGTCCCAGAGGAGATGCAGCTTGCAGTTGACGAGAAGTGCGAGTTCTTGCCTTTTCTTTCACCAAAGAAGGTTCTTGTCAGGGAGGGAAAGATTTGGGCCATGGAATTCTACAAGACAGAACAGTTAGAGGATGGCTCATGGATTGAGGATAAGGAACAAACATTCAAGATAAAAGCCAACTTTGTTATTTCTGCCTTTGGTTCCACGCTGACCGACAGAGATGTTGTCAAGGCCTTGGAGCCCATGAAGTTCAACAAGTGGGGTCTGCCCGAAGTTGATCCATTTTCCATGAGCACGAGCGAAGCTGGAGTCTTTTGTGGGGGAGATGTGGCTGGTGTTGCCAACACTACCGTAGAGAGTACAAACGATGGCAAACAAGCTGCATGGCATATGCACGCGTATTTACAGGCCCTGTATGGTCTGCCAGTGGTCAAAGAACCCAGTCTTCCAAAATTTTACACCGAAGTAGACAATGTGGACCTAAGTGTGGAGATTTGTGGCTTAAGAATTGATAATCCTTTTGGCCTGGCAAGTGCCCCACCCACCACCAGTGCTGCTATGATACGACGTGGCTTTGAAGCAGGCTGGGGATTTGCTGTCACCAAAACATATTCACTTGACAAGGATGCCATAACAAATGTGTCACCTCGTATCGTTCGTGGTACCACTTCTGGCCCCTTGTATGGCCCAGGCCAAGGTGCTTTTCTCAACATAGAGCTGATCAGTGAGAAGACCGCAGCTTACTGGTGCCGATCAGTTACAGAACTGAAAATGGATTTCCCACACAAGGTGTTGATTGCCAGTATTATGTGTGGTTATTCAAAGGAAGATTGGACTGAACTTGCACAGATGTCTGAGAAAGCAGGCGCAGATGCTTTAGAGCTGAACTTGTCTTGTCCGCATGGCATGGGGGAGAGAGGCATGGGACTAGCTTGTGGTCAGGATGCTGAATTGGTGCGGAACATTTGCCGCTGGGTGCGTGCTGCCGTTAAAATTCCGTTTTTTGCCAAGTTAACGCCAAACGTTACAGACATTGTGGACATTGCAAGAGCAGCTCAGGAAGGTTGTGCTGACGGAGTCACAGCGACCAATACAGTCTCTGGTTTGATGGGATTATACCCAAACAGCAGTGCATGGCCTTCTGTGGGCAAGGAAAAAAAGACCACTTATGGGGGTGTGTCTGGCAATGCGATTCGTCCAATTGCATTGCGAGCAGTGTCTGCAATTGCCAAAGCTCTGCCGGGTTTTCCCATCCTGGCTACAGGTGGAGCAGACAGTGCTGAAGCAGTGTTGCAGTTTCTTCATTGCGGTGCCTCTGCAGTCCAGATATCAAGTGCCGTGCAGAACCAGGACTTCACTCTGATTGACGATTACACTTCAGGACTCAAATGCTTGTTGTATCTTCAAACCGTTCGTGAGTTTTCTGAGTGGACTGGACAGAGTCCACCGACGCCAAAACACCAGAAAGGAAAACGTGTTCCGAGAATAGCTGAACTTGTTGGAAAGTCTCTTCCCAATTTTGGACCGTACGCGAGAGAAAGGGAAAAAATTGTGGCAAAGCACAAGGAGGAGATTGACTTGTTGAGTAGAGAGTTCGAACCAGAGGTAGTCAGACCGGCCTACAAACCTGACAAACCAGTTCCACCGGTCAAGGATATCATTGGAGCAGCGCTGGATCGCATTGGTGCTTATGGTGACCTTGACAACAAGCAGCAAGTGGTGGCGCTTATTGACGAAGACTTGTGCATTAACTGCGGCAAATGCTACATGACGTGCAATGACTGTGGTTACCAGGCCATCACGTTTGACCCCCAAACTCATTTGCCGCACGTGACGAAGGATTGCACGGGATGCACGCTTTGCGTGTCAGTCTGCCCCGTGATTGACTGTATCAAAATGGTGCCAAGGGAAGGACCTTACAAACCAAGCCGCGGTGTTCCTCTAGCAGTTAGAAGCTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q12882	Dihydropyrimidine dehydrogenase [NADP(+)] OS=Homo sapiens OX=9606 GN=DPYD PE=1 SV=2
O89000	Dihydropyrimidine dehydrogenase [NADP(+)] OS=Rattus norvegicus OX=10116 GN=Dpyd PE=2 SV=1
Q5R895	Dihydropyrimidine dehydrogenase [NADP(+)] OS=Pongo abelii OX=9601 GN=DPYD PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003103 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07992 all species →	Pyr_redox_2	Pyridine nucleotide-disulphide oxidoreductase	Domain	Interproscan
PF01180 all species →	DHO_dh	Dihydroorotate dehydrogenase	Domain	Interproscan
PF14691 all species →	Fer4_20	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	Domain	Interproscan
PF14697 all species →	Fer4_21	4Fe-4S dicluster domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR023753 all species →	Domain	FAD/NAD(P)-binding domain	Interproscan
IPR017896 all species →	Domain	4Fe-4S ferredoxin-type, iron-sulphur binding domain	Interproscan
IPR017900 all species →	Conserved_site	4Fe-4S ferredoxin, iron-sulphur binding, conserved site	Interproscan
IPR009051 all species →	Homologous_superfamily	Alpha-helical ferredoxin	Interproscan
IPR005720 all species →	Domain	Dihydroorotate dehydrogenase, catalytic	Interproscan
IPR028261 all species →	Domain	Dihydroprymidine dehydrogenase domain II	Interproscan
IPR036188 all species →	Homologous_superfamily	FAD/NAD(P)-binding domain superfamily	Interproscan
IPR013785 all species →	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43073 all species →	DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan
GO:0051536 all species →	Molecular Function	iron-sulfur cluster binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0016627 all species →	Molecular Function	oxidoreductase activity, acting on the CH-CH group of donors	Interproscan
GO:0002058 all species →	Molecular Function	uracil binding	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006210 all species →	Biological Process	thymine catabolic process	Interproscan
GO:0006212 all species →	Biological Process	uracil catabolic process	Interproscan
GO:0017113 all species →	Molecular Function	dihydropyrimidine dehydrogenase (NADP+) activity	Interproscan
GO:0050661 all species →	Molecular Function	NADP binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00207	DPYD; dihydropyrimidine dehydrogenase (NADP+)	EC:1.3.1.2	Drug metabolism - other enzymes	ko00983	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.