Genomic Location: contig_11:531800...564640
NR annotation: XP_022801938.1, bifunctional glutamate/proline--tRNA ligase-like [Stylophora pistillata]
Species Dendrogyra cylindrus · all data for this species · gene families
| CDS |
| FUN_008596-T1 |
| Transcript |
| FUN_008596-T1 |
| Protein |
| FUN_008596-T1 |
| UniProt accession | Description |
|---|---|
| P07814 | Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 |
| Q7SIA2 | Bifunctional glutamate/proline--tRNA ligase OS=Cricetulus griseus OX=10029 GN=EPRS1 PE=1 SV=3 |
| Q8CGC7 | Bifunctional glutamate/proline--tRNA ligase OS=Mus musculus OX=10090 GN=Eprs1 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003095 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00043 all species → | GST_C | Glutathione S-transferase, C-terminal domain | Domain | Interproscan |
| PF03129 all species → | HGTP_anticodon | Anticodon binding domain | Domain | Interproscan |
| PF20974 all species → | tRNA-synt_1c_C2 | tRNA synthetases class I (E and Q), anti-codon binding domain | Domain | Interproscan |
| PF09180 all species → | ProRS-C_1 | Prolyl-tRNA synthetase, C-terminal | Domain | Interproscan |
| PF03950 all species → | tRNA-synt_1c_C | tRNA synthetases class I (E and Q), anti-codon binding domain | Domain | Interproscan |
| PF00749 all species → | tRNA-synt_1c | tRNA synthetases class I (E and Q), catalytic domain | Domain | Interproscan |
| PF00458 all species → | WHEP-TRS | WHEP-TRS domain | Domain | Interproscan |
| PF00587 all species → | tRNA-synt_2b | tRNA synthetase class II core domain (G, H, P, S and T) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004046 all species → | Domain | Glutathione S-transferase, C-terminal | Interproscan |
| IPR004526 all species → | Family | Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic | Interproscan |
| IPR033721 all species → | Domain | Prolyl-tRNA synthetase, catalytic domain | Interproscan |
| IPR016061 all species → | Domain | Proline-tRNA ligase, class II, C-terminal | Interproscan |
| IPR004154 all species → | Domain | Anticodon-binding | Interproscan |
| IPR009068 all species → | Homologous_superfamily | uS15/NS1, RNA-binding domain superfamily | Interproscan |
| IPR000738 all species → | Domain | WHEP-TRS domain | Interproscan |
| IPR049437 all species → | Domain | tRNA synthetases class I (E and Q), anti-codon binding domain | Interproscan |
| IPR011035 all species → | Homologous_superfamily | Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily | Interproscan |
| IPR017449 all species → | Homologous_superfamily | Prolyl-tRNA synthetase, class II | Interproscan |
| IPR045864 all species → | Homologous_superfamily | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | Interproscan |
| IPR006195 all species → | Domain | Aminoacyl-tRNA synthetase, class II | Interproscan |
| IPR004499 all species → | Family | Proline-tRNA ligase, class IIa, archaeal-type | Interproscan |
| IPR020059 all species → | Domain | Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain | Interproscan |
| IPR020061 all species → | Homologous_superfamily | Glutamine-tRNA ligase, alpha-bundle domain superfamily | Interproscan |
| IPR020058 all species → | Domain | Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain | Interproscan |
| IPR020056 all species → | Homologous_superfamily | Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal | Interproscan |
| IPR002314 all species → | Domain | Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) | Interproscan |
| IPR001412 all species → | Conserved_site | Aminoacyl-tRNA synthetase, class I, conserved site | Interproscan |
| IPR036621 all species → | Homologous_superfamily | Anticodon-binding domain superfamily | Interproscan |
| IPR036282 all species → | Homologous_superfamily | Glutathione S-transferase, C-terminal domain superfamily | Interproscan |
| IPR000924 all species → | Family | Glutamyl/glutaminyl-tRNA synthetase | Interproscan |
| IPR014729 all species → | Homologous_superfamily | Rossmann-like alpha/beta/alpha sandwich fold | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43382 all species → | PROLYL-TRNA SYNTHETASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000166 all species → | Molecular Function | nucleotide binding | Interproscan |
| GO:0004818 all species → | Molecular Function | glutamate-tRNA ligase activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0006424 all species → | Biological Process | glutamyl-tRNA aminoacylation | Interproscan |
| GO:0004827 all species → | Molecular Function | proline-tRNA ligase activity | Interproscan |
| GO:0006433 all species → | Biological Process | prolyl-tRNA aminoacylation | Interproscan |
| GO:0004812 all species → | Molecular Function | aminoacyl-tRNA ligase activity | Interproscan |
| GO:0006418 all species → | Biological Process | tRNA aminoacylation for protein translation | Interproscan |
| GO:0006412 all species → | Biological Process | translation | Interproscan |
| GO:0043039 all species → | Biological Process | tRNA aminoacylation | Interproscan |
| GO:0017101 all species → | Cellular Component | aminoacyl-tRNA synthetase multienzyme complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K14163 | EPRS; bifunctional glutamyl/prolyl-tRNA synthetase | EC:6.1.1.17 EC:6.1.1.15 | Transfer RNA biogenesis | ko03016 | deepkoala |
Genes whose expression across the transcriptome samples of Dendrogyra cylindrus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Dendrogyra cylindrus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |