Detailed information of FUN_008596-T1 in Dendrogyra cylindrus

Genomic Location: contig_11:531800...564640
NR annotation: XP_022801938.1, bifunctional glutamate/proline--tRNA ligase-like [Stylophora pistillata]
Species Dendrogyra cylindrus · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P07814Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5
Q7SIA2Bifunctional glutamate/proline--tRNA ligase OS=Cricetulus griseus OX=10029 GN=EPRS1 PE=1 SV=3
Q8CGC7Bifunctional glutamate/proline--tRNA ligase OS=Mus musculus OX=10090 GN=Eprs1 PE=1 SV=4
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003095 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00043
all species →
GST_CGlutathione S-transferase, C-terminal domainDomainInterproscan
PF03129
all species →
HGTP_anticodonAnticodon binding domainDomainInterproscan
PF20974
all species →
tRNA-synt_1c_C2tRNA synthetases class I (E and Q), anti-codon binding domainDomainInterproscan
PF09180
all species →
ProRS-C_1Prolyl-tRNA synthetase, C-terminalDomainInterproscan
PF03950
all species →
tRNA-synt_1c_CtRNA synthetases class I (E and Q), anti-codon binding domainDomainInterproscan
PF00749
all species →
tRNA-synt_1ctRNA synthetases class I (E and Q), catalytic domainDomainInterproscan
PF00458
all species →
WHEP-TRSWHEP-TRS domainDomainInterproscan
PF00587
all species →
tRNA-synt_2btRNA synthetase class II core domain (G, H, P, S and T)DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR004046
all species →
DomainGlutathione S-transferase, C-terminalInterproscan
IPR004526
all species →
FamilyGlutamyl-tRNA synthetase, archaeal/eukaryotic cytosolicInterproscan
IPR033721
all species →
DomainProlyl-tRNA synthetase, catalytic domainInterproscan
IPR016061
all species →
DomainProline-tRNA ligase, class II, C-terminalInterproscan
IPR004154
all species →
DomainAnticodon-bindingInterproscan
IPR009068
all species →
Homologous_superfamilyuS15/NS1, RNA-binding domain superfamilyInterproscan
IPR000738
all species →
DomainWHEP-TRS domainInterproscan
IPR049437
all species →
DomaintRNA synthetases class I (E and Q), anti-codon binding domainInterproscan
IPR011035
all species →
Homologous_superfamilyLarge ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamilyInterproscan
IPR017449
all species →
Homologous_superfamilyProlyl-tRNA synthetase, class IIInterproscan
IPR045864
all species →
Homologous_superfamilyClass II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)Interproscan
IPR006195
all species →
DomainAminoacyl-tRNA synthetase, class IIInterproscan
IPR004499
all species →
FamilyProline-tRNA ligase, class IIa, archaeal-typeInterproscan
IPR020059
all species →
DomainGlutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domainInterproscan
IPR020061
all species →
Homologous_superfamilyGlutamine-tRNA ligase, alpha-bundle domain superfamilyInterproscan
IPR020058
all species →
DomainGlutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domainInterproscan
IPR020056
all species →
Homologous_superfamilyLarge ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminalInterproscan
IPR002314
all species →
DomainAminoacyl-tRNA synthetase, class II (G/ P/ S/T)Interproscan
IPR001412
all species →
Conserved_siteAminoacyl-tRNA synthetase, class I, conserved siteInterproscan
IPR036621
all species →
Homologous_superfamilyAnticodon-binding domain superfamilyInterproscan
IPR036282
all species →
Homologous_superfamilyGlutathione S-transferase, C-terminal domain superfamilyInterproscan
IPR000924
all species →
FamilyGlutamyl/glutaminyl-tRNA synthetaseInterproscan
IPR014729
all species →
Homologous_superfamilyRossmann-like alpha/beta/alpha sandwich foldInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43382
all species →
PROLYL-TRNA SYNTHETASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000166
all species →
Molecular Functionnucleotide bindingInterproscan
GO:0004818
all species →
Molecular Functionglutamate-tRNA ligase activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0006424
all species →
Biological Processglutamyl-tRNA aminoacylationInterproscan
GO:0004827
all species →
Molecular Functionproline-tRNA ligase activityInterproscan
GO:0006433
all species →
Biological Processprolyl-tRNA aminoacylationInterproscan
GO:0004812
all species →
Molecular Functionaminoacyl-tRNA ligase activityInterproscan
GO:0006418
all species →
Biological ProcesstRNA aminoacylation for protein translationInterproscan
GO:0006412
all species →
Biological ProcesstranslationInterproscan
GO:0043039
all species →
Biological ProcesstRNA aminoacylationInterproscan
GO:0017101
all species →
Cellular Componentaminoacyl-tRNA synthetase multienzyme complexInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K14163EPRS; bifunctional glutamyl/prolyl-tRNA synthetaseEC:6.1.1.17
EC:6.1.1.15
Transfer RNA biogenesisko03016deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Dendrogyra cylindrus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Dendrogyra cylindrus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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