Gene detail

Detailed information of FUN_011976-T1 in Acropora pulchra

Genomic Location: ptg000008l:3771109...3775417
NR annotation: XP_029187083.2, extracellular calcium-sensing receptor-like [Acropora millepora]
Species Acropora pulchra · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

FUN_011976-T1

ATGTTGGTAATAAGCAGCTATGATAACTTCCACTCTGGAGTTTTGGGAGCGGTGATTTTTTGTCTTGTTTTGCCACATGTCACCTTGGCAAGCGAAACTGCTCCGGGACAAAGAATTTATAAGACAGGCCACGTAGTTATCGGCGGTCTTTTTCCTGTACACGTGCGTGGAGATTTTAGATCGAAATATATGTCGCTGGCCGAAGCTATGATATTTGCAATCGAACAAATCAACAACGACTCTTCAATTTTGCCTAACGTTACTCTGGGCTATGATATCACAGATACGAACCTTACAAATCGCCATGCAATGAACTCTTCCTTGGATTACGTGAATGTTCACAAATTTGCATTTATTGATCCAGCTTTCAACAGGACGTGTGCCATTTTGCCAAAAGAACAGCTGGCCCCTGTCGTGGCAGTTGTGGGAACTGGAACTTCTCGGTCCTCCATTCTCGTGTCTAATTTGCTGGAAGTCGAGGATATACCACTGATTAGTTATGCCGCCACCAGCGACGAACTGAGTAGTAGCGCATATCCATCTTTCTTTCGCACCGTGCCTCCAGATCGTTTTCAATCCACAGTAATGTCGGATATCGCGAAGCACTTTCATTGGACCTACGTGGCCGCCGTAGCCGCTGACGACGCTTACGGAAGATCAGGCATCGAATTTTTCCGCAAGCAATCGAAGCTCCAAGGAATATGCATCGCTTACAACAATTTCTTCCCCATTAACGACGAGAAAGATGCTAAAATTAAGACAATTATCGAAGACCTTAAGAAACTGGAAAATGTGGGCGTGATTGTCTTATATTGTGATAGCACGTCTGCTCTCAGCGTGTTGAGAGAAGCGAAAAGCCAGAAGCTTGAAGGAAGAATTTGGATCGCTAGCGAAGCTTGGGGGAATAACGACAAAGTTATTCACGAAAAGGAGCTTCAGCCAGTTCTTAAAGGAATGTTAGGGGTTGTTTTTACCGATATTACTGTCCCCTCGTATAAGAGATATCTGCTTTCACGCACGTCCCTTTACAGATCCAACCCGTGGTGGAGGGTATTCTGGGAAGACCAGTATGGGTGTACGTTTAATGTCACGCTCTCCACGAGTAGTAACAAGGCACTATGCTCGGACAACCTGAAAGTCACGGAAGATATATTTGATGAGAAACTGTATGATAGCAAGACTACTTATGTTATCAACGCTGTCTACGCGATCGCGCATGCATTAGACGCGATTTTCAAGTGTAAATTTCCTTCAACGGATCATTGCCCGCAAACGAAACCCTTTGTCGAACCGAGAGATGTCTTGGAATACTTGAAGAAAGTTAACTTCTCAACTGAAACGTCCAGGGTCTTTTTTGATGAAAACGGCGACTCCTTAGCTACTTACAGTATCATCAACTATCGAGTTGACAAAGACACTGGCGGCCGCGTGGAGACGGTAGGGACTTGGGAAGCACAGAGGCTCAACCTTAACTCCAGTGCTATAGTTTGGAACAACGGGATGACGGGTAAAATCCCGCGATCTGTTTGCAGTGAGACATGCAAGCCTGGATTCCGGCAGACTGAGGAGATAAACTGTTGTTGGCAGTGCATCAAATGTTCCCAGGACACTGTATCGAGCAAACACGGAGCAAGGAATTGCACACCGTGTCCAGCGGATTACATCTCGAATGAGAAACGGACAAAATGCCATGCTATACCCGTAGAGCGCATCCTCTGGGGGGATCCCATTGGGATCATGATAACCTTTTTCGCCTGTTTGGGAGTGGTGGCTACAGCTCTTGTCGGAGCTATGTTCATATGGCAAAACAACACACCGATTGTAAAAGCCTCCAATCGAGAACTCAGTTACCTGTTCCTCTTTAGCATTGGAATGACTTATCTGTGGGCGCTGATAAATTTAGCCGAACCCAGCGATTTTATCTGTCCGTTATCAGAGGCGTGGTTTTATGTCTTTTACACCATTGCTGTCGTCGTGCTGGGCGTCAAGACCAAACGCATCGTACACCTGTTTGAGCACCGCGTTCCACGTTCCGAGCTCAGCAAAAATTTCATCGAGAAGCGCAAACACATTCTCATTATCATCGGCATTCTGGGGTCAGACGTTTTAATTCTGGTCATTTGGTTTCTTCTGGATCCCCCTCATCCTGAAATCGACAAATCTGTGAGAACGTCTCATTATCTCGGCTGCAAGGTTACGTCTAACGTCGCAGGTAGCTTCTGCCGCTACCTCCTCATAGCAATTCTCGTCACCATGGCATTTGTCTGTTGTTACTTCGCGTTCAAATCCAGGAAGCTGCCGCACAATTTTAACGAGGGTAAATTCATTGCGTTCGCACTGTACGTTCTCGTGATCTCTTGGGTGACATTCTATCCCGTTTCTTTGACCATACGCGGCAAGTTTACGGTCGTGGTGTCTGGATCGTCGTCCATCATTTCCGCGTCTGGTCTTCTTGTGTGTATCTTCGTGCCCAAGATGTACATCATTCTTTTACACCCAGAGAAAAACACGGTGGCTTACATGAAGAGCCAAATTTCCAACCACATCTTCCGTCAGAGCACTGCCGACAGGAATTCCCGACAAAAATCCTGTCCACCTGATAGTGTTCACTCCGTGCATGGATCAGCAACAACCGCAACCCCTCTGGATACCCCGAGATACCTTGAATCCCCCAAACTTTCAAATCCCGGTGACCTTGAAAGCAGTAATAAGGTTATCTCTTACTTATGA

Transcript

FUN_011976-T1

TCGGGCTGAAAAAGTGATAGCCGATTACATGGATTTTTCAGTCCGTTTCACCGGACTGAAAATCCTAGCCTAGTTTCAGAAACCGGGCTATGATTTTCAGCCCGGGCTGAAACCTTCTTCATGTAATCGCCACTTTCATTTTAAGAGAATTTCTTTCAGAGCACGAGTTGTGGTCTCAGCCCGGCTAACCGTGCTGAAATTCGCCATGTAATCGGGCCCTTAGGACAATTAATTTCCTTATCACTCTGACTTGATCGTTTCCCGACTCACATCAAGTGACTTTTACCAGCCTGAGCTTCCGCTAACAAAATCGTGATTTCAACACACGCACACAGACATATATATTTGTATATATATGATTCAAGTGGAGAAATATTTTATTCGTGCCATGAGCCCTTCAAAGTGGAATTTACAATTTTAATTTGTTAATGGTTTCGTCTGTTTACCCAACTAAAATAATAAGAAACTACATGATAAAAAGAGATAACCAAACTCGTTTCGGGAACTATTCGTGGGTAAAATAATTTATGGAAGATCAACAAGGCTCGATAATGAACTAGCGACAAAATCTACATAGCACGGATTTTAATCAACCTTTGAGATTTATTTGATTTGACCATTATTGATCCATTTTTATAATAATAAACCAGTGGTGGTGTATGTTTCCCATACACCCTTCTCGCTCACTGCATCCGAAACTTCACTAAAAGATGACAGAATAATGTGAAAGCGCATATCGATGTTTTAACTAGAAGGTTCGGTACTCGTGCGTTAGAATTTTCTTTTTAACACCACAGAGATGCCACAAGTCTTAAGAAGCCAGAGTCCTTACCAGACTGAAAATCTCGTACTAGCAATTGTGTGTCCGTATAGATCTCCCGAAACTCATTCACACAGATCATAAGTTATAAATAATTTTTGATTGACGTTTGTCGGACAAATTCTCAAACTTCCGCAAGATTTCACCATTAGTGCAAGAGCAGGGAAAGGCAACTCGCTTCTAGAAAGTCTGGGCTTCAAGTTCTGTTAATTTGTAACCAACCAAGATTGATTTTCAGAGGACAAAAGAAACGGCGAATAAGCAAGGGGCGACAAGGGATTTGTAATTAAACGAAGCATCAACGACTTTAAAATCTTGACGATGTTGGTAATAAGCAGCTATGATAACTTCCACTCTGGAGTTTTGGGAGCGGTGATTTTTTGTCTTGTTTTGCCACATGTCACCTTGGCAAGCGAAACTGCTCCGGGACAAAGAATTTATAAGACAGGCCACGTAGTTATCGGCGGTCTTTTTCCTGTACACGTGCGTGGAGATTTTAGATCGAAATATATGTCGCTGGCCGAAGCTATGATATTTGCAATCGAACAAATCAACAACGACTCTTCAATTTTGCCTAACGTTACTCTGGGCTATGATATCACAGATACGAACCTTACAAATCGCCATGCAATGAACTCTTCCTTGGATTACGTGAATGTTCACAAATTTGCATTTATTGATCCAGCTTTCAACAGGACGTGTGCCATTTTGCCAAAAGAACAGCTGGCCCCTGTCGTGGCAGTTGTGGGAACTGGAACTTCTCGGTCCTCCATTCTCGTGTCTAATTTGCTGGAAGTCGAGGATATACCACTGATTAGTTATGCCGCCACCAGCGACGAACTGAGTAGTAGCGCATATCCATCTTTCTTTCGCACCGTGCCTCCAGATCGTTTTCAATCCACAGTAATGTCGGATATCGCGAAGCACTTTCATTGGACCTACGTGGCCGCCGTAGCCGCTGACGACGCTTACGGAAGATCAGGCATCGAATTTTTCCGCAAGCAATCGAAGCTCCAAGGAATATGCATCGCTTACAACAATTTCTTCCCCATTAACGACGAGAAAGATGCTAAAATTAAGACAATTATCGAAGACCTTAAGAAACTGGAAAATGTGGGCGTGATTGTCTTATATTGTGATAGCACGTCTGCTCTCAGCGTGTTGAGAGAAGCGAAAAGCCAGAAGCTTGAAGGAAGAATTTGGATCGCTAGCGAAGCTTGGGGGAATAACGACAAAGTTATTCACGAAAAGGAGCTTCAGCCAGTTCTTAAAGGAATGTTAGGGGTTGTTTTTACCGATATTACTGTCCCCTCGTATAAGAGATATCTGCTTTCACGCACGTCCCTTTACAGATCCAACCCGTGGTGGAGGGTATTCTGGGAAGACCAGTATGGGTGTACGTTTAATGTCACGCTCTCCACGAGTAGTAACAAGGCACTATGCTCGGACAACCTGAAAGTCACGGAAGATATATTTGATGAGAAACTGTATGATAGCAAGACTACTTATGTTATCAACGCTGTCTACGCGATCGCGCATGCATTAGACGCGATTTTCAAGTGTAAATTTCCTTCAACGGATCATTGCCCGCAAACGAAACCCTTTGTCGAACCGAGAGATGTCTTGGAATACTTGAAGAAAGTTAACTTCTCAACTGAAACGTCCAGGGTCTTTTTTGATGAAAACGGCGACTCCTTAGCTACTTACAGTATCATCAACTATCGAGTTGACAAAGACACTGGCGGCCGCGTGGAGACGGTAGGGACTTGGGAAGCACAGAGGCTCAACCTTAACTCCAGTGCTATAGTTTGGAACAACGGGATGACGGGTAAAATCCCGCGATCTGTTTGCAGTGAGACATGCAAGCCTGGATTCCGGCAGACTGAGGAGATAAACTGTTGTTGGCAGTGCATCAAATGTTCCCAGGACACTGTATCGAGCAAACACGGAGCAAGGAATTGCACACCGTGTCCAGCGGATTACATCTCGAATGAGAAACGGACAAAATGCCATGCTATACCCGTAGAGCGCATCCTCTGGGGGGATCCCATTGGGATCATGATAACCTTTTTCGCCTGTTTGGGAGTGGTGGCTACAGCTCTTGTCGGAGCTATGTTCATATGGCAAAACAACACACCGATTGTAAAAGCCTCCAATCGAGAACTCAGTTACCTGTTCCTCTTTAGCATTGGAATGACTTATCTGTGGGCGCTGATAAATTTAGCCGAACCCAGCGATTTTATCTGTCCGTTATCAGAGGCGTGGTTTTATGTCTTTTACACCATTGCTGTCGTCGTGCTGGGCGTCAAGACCAAACGCATCGTACACCTGTTTGAGCACCGCGTTCCACGTTCCGAGCTCAGCAAAAATTTCATCGAGAAGCGCAAACACATTCTCATTATCATCGGCATTCTGGGGTCAGACGTTTTAATTCTGGTCATTTGGTTTCTTCTGGATCCCCCTCATCCTGAAATCGACAAATCTGTGAGAACGTCTCATTATCTCGGCTGCAAGGTTACGTCTAACGTCGCAGGTAGCTTCTGCCGCTACCTCCTCATAGCAATTCTCGTCACCATGGCATTTGTCTGTTGTTACTTCGCGTTCAAATCCAGGAAGCTGCCGCACAATTTTAACGAGGGTAAATTCATTGCGTTCGCACTGTACGTTCTCGTGATCTCTTGGGTGACATTCTATCCCGTTTCTTTGACCATACGCGGCAAGTTTACGGTCGTGGTGTCTGGATCGTCGTCCATCATTTCCGCGTCTGGTCTTCTTGTGTGTATCTTCGTGCCCAAGATGTACATCATTCTTTTACACCCAGAGAAAAACACGGTGGCTTACATGAAGAGCCAAATTTCCAACCACATCTTCCGTCAGAGCACTGCCGACAGGAATTCCCGACAAAAATCCTGTCCACCTGATAGTGTTCACTCCGTGCATGGATCAGCAACAACCGCAACCCCTCTGGATACCCCGAGATACCTTGAATCCCCCAAACTTTCAAATCCCGGTGACCTTGAAAGCAGTAATAAGGTTATCTCTTACTTATGAGGTCGTTTTACGCTACAATCGTCTTCCTTTGGATAGTCTTCATTTGTAACATTTCGGAACTCAAGCAACGCCGAAGTAAACTTAAAAAAGAACGTCAAAACAAATTTGTAGAAAGAACAAAAGTAACTTTGCTGCTCGCCTTGCCTGTGTGTTGCCCATTTTTTCTTCCAATCGAGTATGCAAAGAACTACTTTGAATTTTGTCCTCTGTCTCTCACACGCTATGGATATCTTTGTGACCCGTTTCTCACTGACACAAGTCACATCTCGAACACTTAGAGCAACAATTCTTTTCCATTTAGCACATGACAGCAAGGCTTGGTAGGCTAATTTGCACAAGGACAAAAGAATAATGAACTGGCAGCCATTTATGAATAAGGTCTACATTTTGGACAAATTACTTTTTATCTTCTTGAGAGAAAAATAAAAAATAAAGATT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P48442	Extracellular calcium-sensing receptor OS=Rattus norvegicus OX=10116 GN=Casr PE=1 SV=1
Q9QY96	Extracellular calcium-sensing receptor OS=Mus musculus OX=10090 GN=Casr PE=1 SV=2
O62714	Extracellular calcium-sensing receptor OS=Sus scrofa OX=9823 GN=CASR PE=2 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000269 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01094 all species →	ANF_receptor	Receptor family ligand binding region	Family	Interproscan
PF07562 all species →	NCD3G	Nine Cysteines Domain of family 3 GPCR	Family	Interproscan
PF00003 all species →	7tm_3	7 transmembrane sweet-taste receptor of 3 GCPR	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000337 all species →	Family	GPCR, family 3	Interproscan
IPR050726 all species →	Family	Metabotropic Glutamate Receptor	Interproscan
IPR000068 all species →	Family	GPCR, family 3, extracellular calcium-sensing receptor-related	Interproscan
IPR009030 all species →	Homologous_superfamily	Growth factor receptor cysteine-rich domain superfamily	Interproscan
IPR017978 all species →	Domain	GPCR family 3, C-terminal	Interproscan
IPR038550 all species →	Homologous_superfamily	GPCR, family 3, nine cysteines domain superfamily	Interproscan
IPR001828 all species →	Domain	Receptor, ligand binding region	Interproscan
IPR011500 all species →	Domain	GPCR, family 3, nine cysteines domain	Interproscan
IPR028082 all species →	Homologous_superfamily	Periplasmic binding protein-like I	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24060 all species →	METABOTROPIC GLUTAMATE RECEPTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004930 all species →	Molecular Function	G protein-coupled receptor activity	Interproscan
GO:0007186 all species →	Biological Process	G protein-coupled receptor signaling pathway	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0001640 all species →	Molecular Function	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	Interproscan
GO:0005887 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007216 all species →	Biological Process	G protein-coupled glutamate receptor signaling pathway	Interproscan
GO:0051966 all species →	Biological Process	regulation of synaptic transmission, glutamatergic	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04606	GRM3; metabotropic glutamate receptor 3	-	G protein-coupled receptors	ko04030	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Acropora pulchra tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Acropora pulchra, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →