Detailed information of FUN_014427-T2 in Dendrogyra cylindrus

Genomic Location: contig_22:4193841...4242338
NR annotation: XP_027048503.1, serine/threonine-protein kinase MRCK alpha-like [Pocillopora damicornis]
Species Dendrogyra cylindrus · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q5VT25Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens OX=9606 GN=CDC42BPA PE=1 SV=1
Q3UU96Serine/threonine-protein kinase MRCK alpha OS=Mus musculus OX=10090 GN=Cdc42bpa PE=1 SV=2
O54874Serine/threonine-protein kinase MRCK alpha OS=Rattus norvegicus OX=10116 GN=Cdc42bpa PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002040 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00130
all species →
C1_1Phorbol esters/diacylglycerol binding domain (C1 domain)DomainInterproscan
PF15796
all species →
KELKKELK-motif containing domain of MRCK Ser/Thr protein kinaseCoiled-coilInterproscan
PF01576
all species →
Myosin_tail_1Myosin tailCoiled-coilInterproscan
PF08826
all species →
DMPK_coilDMPK coiled coil domain likeCoiled-coilInterproscan
PF00780
all species →
CNHCNH domainRepeatInterproscan
PF00433
all species →
Pkinase_CProtein kinase C terminal domainFamilyInterproscan
PF00069
all species →
PkinaseProtein kinase domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000961
all species →
DomainAGC-kinase, C-terminalInterproscan
IPR000719
all species →
DomainProtein kinase domainInterproscan
IPR001180
all species →
DomainCitron homology (CNH) domainInterproscan
IPR002219
all species →
DomainProtein kinase C-like, phorbol ester/diacylglycerol-binding domainInterproscan
IPR011993
all species →
Homologous_superfamilyPH-like domain superfamilyInterproscan
IPR000095
all species →
DomainCRIB domainInterproscan
IPR036322
all species →
Homologous_superfamilyWD40-repeat-containing domain superfamilyInterproscan
IPR001849
all species →
DomainPleckstrin homology domainInterproscan
IPR008271
all species →
Active_siteSerine/threonine-protein kinase, active siteInterproscan
IPR031597
all species →
DomainKELK-motif containing domainInterproscan
IPR017441
all species →
Binding_siteProtein kinase, ATP binding siteInterproscan
IPR050839
all species →
FamilyRho-associated Serine/Threonine KinaseInterproscan
IPR002928
all species →
DomainMyosin tailInterproscan
IPR014930
all species →
DomainMyotonic dystrophy protein kinase, coiled coilInterproscan
IPR017892
all species →
DomainProtein kinase, C-terminalInterproscan
IPR046349
all species →
Homologous_superfamilyC1-like domain superfamilyInterproscan
IPR011009
all species →
Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR22988
all species →
MYOTONIC DYSTROPHY S/T KINASE-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004674
all species →
Molecular Functionprotein serine/threonine kinase activityInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0006468
all species →
Biological Processprotein phosphorylationInterproscan
GO:0004672
all species →
Molecular Functionprotein kinase activityInterproscan
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0005856
all species →
Cellular ComponentcytoskeletonInterproscan
GO:0018107
all species →
Biological Processpeptidyl-threonine phosphorylationInterproscan
GO:0031032
all species →
Biological Processactomyosin structure organizationInterproscan
GO:0016459
all species →
Cellular Componentmyosin complexInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K16307CDC42BP; serine/threonine-protein kinase MRCKEC:2.7.11.1
Protein kinasesko01001deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Dendrogyra cylindrus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Dendrogyra cylindrus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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