Genomic Location: ptg000009l:3713137...3738056
NR annotation: XP_029195436.2, pre-mRNA-processing-splicing factor 8 [Acropora millepora]
Species abbreviation APULC · all data for this species · gene families
| CDS |
| FUN_014855-T1 |
| Transcript |
| FUN_014855-T1 |
| Protein |
| FUN_014855-T1 |
| UniProt accession | Description |
|---|---|
| Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 |
| Q99PV0 | Pre-mRNA-processing-splicing factor 8 OS=Mus musculus OX=10090 GN=Prpf8 PE=1 SV=2 |
| P34369 | Pre-mRNA-splicing factor 8 homolog OS=Caenorhabditis elegans OX=6239 GN=prp-8 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004404 (this species only) |
| Ubiquitin family | UBD|Other|Jab_MPN · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08082 all species → | PRO8NT | PRO8NT (NUC069), PrP8 N-terminal domain | Domain | Interproscan |
| PF10598 all species → | RRM_4 | RNA recognition motif of the spliceosomal PrP8 | Domain | Interproscan |
| PF12134 all species → | PRP8_domainIV | PRP8 domain IV core | Domain | Interproscan |
| PF08083 all species → | PROCN | PROCN (NUC071) domain | Domain | Interproscan |
| PF10597 all species → | U5_2-snRNA_bdg | U5-snRNA binding site 2 of PrP8 | Domain | Interproscan |
| PF01398 all species → | JAB | JAB1/Mov34/MPN/PAD-1 ubiquitin protease | Family | Interproscan |
| PF10596 all species → | U6-snRNA_bdg | U6-snRNA interacting domain of PrP8 | Domain | Interproscan |
| PF08084 all species → | PROCT | PROCT (NUC072) domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR012591 all species → | Domain | PRO8NT domain | Interproscan |
| IPR019582 all species → | Domain | RNA recognition motif, spliceosomal PrP8 | Interproscan |
| IPR012337 all species → | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR021983 all species → | Domain | PRP8 domain IV core | Interproscan |
| IPR012592 all species → | Domain | PROCN domain | Interproscan |
| IPR019581 all species → | Domain | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding | Interproscan |
| IPR000555 all species → | Domain | JAB1/MPN/MOV34 metalloenzyme domain | Interproscan |
| IPR019580 all species → | Domain | Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding | Interproscan |
| IPR027652 all species → | Family | Pre-mRNA-processing-splicing factor 8 | Interproscan |
| IPR042516 all species → | Homologous_superfamily | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily | Interproscan |
| IPR037518 all species → | Domain | MPN domain | Interproscan |
| IPR043172 all species → | Homologous_superfamily | Prp8 RNase domain IV, palm region | Interproscan |
| IPR043173 all species → | Homologous_superfamily | Prp8 RNase domain IV, fingers region | Interproscan |
| IPR012984 all species → | Domain | PROCT domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11140 all species → | PRE-MRNA SPLICING FACTOR PRP8 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000398 all species → | Biological Process | mRNA splicing, via spliceosome | Interproscan |
| GO:0003723 all species → | Molecular Function | RNA binding | Interproscan |
| GO:0030623 all species → | Molecular Function | U5 snRNA binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0008233 all species → | Molecular Function | peptidase activity | Interproscan |
| GO:0008237 all species → | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0017070 all species → | Molecular Function | U6 snRNA binding | Interproscan |
| GO:0000244 all species → | Biological Process | spliceosomal tri-snRNP complex assembly | Interproscan |
| GO:0005681 all species → | Cellular Component | spliceosomal complex | Interproscan |
| GO:0005682 all species → | Cellular Component | U5 snRNP | Interproscan |
| GO:0030619 all species → | Molecular Function | U1 snRNA binding | Interproscan |
| GO:0030620 all species → | Molecular Function | U2 snRNA binding | Interproscan |
| GO:0071013 all species → | Cellular Component | catalytic step 2 spliceosome | Interproscan |
| GO:0097157 all species → | Molecular Function | pre-mRNA intronic binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K12856 | PRPF8, PRP8; pre-mRNA-processing factor 8 | - | Spliceosome | ko03041 | deepkoala |