Detailed information of FUN_021215-T1 in Siderastrea siderea

Genomic Location: contig_19:3991585...3997235
NR annotation: no NCBI-NR hit recorded
Species Siderastrea siderea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0000595 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00112
all species →
Peptidase_C1Papain family cysteine proteaseDomainInterproscan
PF08246
all species →
Inhibitor_I29Cathepsin propeptide inhibitor domain (I29)DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR013201
all species →
DomainCathepsin propeptide inhibitor domain (I29)Interproscan
IPR000668
all species →
DomainPeptidase C1A, papain C-terminalInterproscan
IPR025661
all species →
Active_siteCysteine peptidase, asparagine active siteInterproscan
IPR000169
all species →
Active_siteCysteine peptidase, cysteine active siteInterproscan
IPR013128
all species →
FamilyPeptidase C1AInterproscan
IPR025660
all species →
Active_siteCysteine peptidase, histidine active siteInterproscan
IPR038765
all species →
Homologous_superfamilyPapain-like cysteine peptidase superfamilyInterproscan
IPR039417
all species →
DomainPapain-like cysteine endopeptidaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR12411
all species →
CYSTEINE PROTEASE FAMILY C1-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0006508
all species →
Biological ProcessproteolysisInterproscan
GO:0008234
all species →
Molecular Functioncysteine-type peptidase activityInterproscan
GO:0004197
all species →
Molecular Functioncysteine-type endopeptidase activityInterproscan
GO:0005615
all species →
Cellular Componentextracellular spaceInterproscan
GO:0005764
all species →
Cellular ComponentlysosomeInterproscan
GO:0006955
all species →
Biological Processimmune responseInterproscan
GO:0008656
all species →
Molecular Functioncysteine-type endopeptidase activator activity involved in apoptotic processInterproscan
GO:0010952
all species →
Biological Processpositive regulation of peptidase activityInterproscan
GO:0051603
all species →
Biological Processproteolysis involved in protein catabolic processInterproscan
GO:2001235
all species →
Biological Processpositive regulation of apoptotic signaling pathwayInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01365CTSL; cathepsin LEC:3.4.22.15
Glycosylphosphatidylinositol (GPI)-anchored proteinsko00537deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of FUN_021215-T1 across 85 RNA-seq samples of Siderastrea siderea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

85Samples
70TPM > 0
7Conditions
1,168.2Max TPM
411.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
holobiont · low.pH_high.temp 20 19 519.44 1,168.22
holobiont · low.pH Control.temp 20 14 265.55 967.73
holobiont · control.pH_high.temp 20 16 385.67 1,046.43
holobiont · control.pH Control.temp 19 15 355.63 920.48
Whole organism 4 4 802.58 1,018.23
unannotated 1 1 738.17 738.17
live coral tissue/skeleton 1 1 844.60 844.60

Per sample · hover a bar for the full sample record

Show the sample table (85 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR22214413 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 1,168.22
SRR22214406 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 840.23
SRR22214410 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 824.18
SRR22214420 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 820.86
SRR22214423 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 677.04
SRR22214418 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 663.39
SRR22214403 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 634.03
SRR22214417 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 550.29
SRR22214412 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 548.32
SRR22214408 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 515.57
SRR22214414 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 478.30
SRR22214404 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 423.68
SRR22214415 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 422.06
SRR22214419 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 386.32
SRR22214402 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 331.93
SRR22214407 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 314.39
SRR22214409 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 293.53
SRR22214421 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 264.04
SRR22214405 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 232.45
SRR22214416 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214429 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 967.73
SRR22214436 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 548.21
SRR22214425 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 516.06
SRR22214441 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 414.86
SRR22214439 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 403.87
SRR22214442 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 369.61
SRR22214428 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 351.16
SRR22214434 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 321.24
SRR22214437 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 299.52
SRR22214424 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 287.76
SRR22214440 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 266.52
SRR22214430 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 255.73
SRR22214426 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 167.01
SRR22214443 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 141.76
SRR22214427 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214431 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214432 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214435 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214438 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214445 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214461 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 1,046.43
SRR22214454 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 794.94
SRR22214447 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 639.00
SRR22214453 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 590.34
SRR22214448 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 538.00
SRR22214458 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 528.23
SRR22214449 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 492.95
SRR22214464 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 481.58
SRR22214462 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 479.84
SRR22214465 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 468.73
SRR22214459 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 324.43
SRR22214450 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 315.63
SRR22214463 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 310.09
SRR22214467 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 249.75
SRR22214457 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 230.53
SRR22214456 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 222.99
SRR22214446 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214451 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214452 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214460 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214535 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 920.48
SRR22214466 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 771.78
SRR22214400 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 637.53
SRR22214506 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 637.43
SRR22214469 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 518.76
SRR22214468 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 457.03
SRR22214548 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 440.94
SRR22214411 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 440.12
SRR22214547 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 423.39
SRR22214481 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 300.84
SRR22214444 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 278.70
SRR22214455 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 248.07
SRR22214470 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 243.90
SRR22214471 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 228.80
SRR22214492 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 209.26
SRR22214422 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214433 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214524 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214546 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR14295600 Whole organism Whole organism not recorded not recorded SRP315757 1,018.23
SRR14295603 Whole organism Whole organism not recorded not recorded SRP315757 903.48
SRR14295604 Whole organism Whole organism not recorded not recorded SRP315757 650.40
SRR14295601 Whole organism Whole organism not recorded not recorded SRP315757 638.22
ERR12861049 unannotated not recorded not recorded not recorded ERP159209 738.17
SRR12454619 live coral tissue/skeleton live coral tissue/skeleton not recorded not recorded SRP277390 844.60

Source: CnidoSite RNA-seq expression matrices (SSIDE_TPM, StringTie quantification over 85 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Siderastrea siderea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated0not in this network-
Negatively correlated341FUN_017364-T1-0.589660208418832

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Siderastrea siderea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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