Genomic Location: ptg000017l:6741758...6757175
NR annotation: XP_015754820.1, PREDICTED: histone-lysine N-methyltransferase NSD2-like isoform X1 [Acropora digitifera]
Species Acropora pulchra · all data for this species · gene families
| CDS |
| FUN_023369-T1 |
| Transcript |
| FUN_023369-T1 |
| Protein |
| FUN_023369-T1 |
| UniProt accession | Description |
|---|---|
| O96028 | Histone-lysine N-methyltransferase NSD2 OS=Homo sapiens OX=9606 GN=NSD2 PE=1 SV=1 |
| Q8BVE8 | Histone-lysine N-methyltransferase NSD2 OS=Mus musculus OX=10090 GN=Nsd2 PE=1 SV=2 |
| Q9BZ95 | Histone-lysine N-methyltransferase NSD3 OS=Homo sapiens OX=9606 GN=NSD3 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002889 (this species only) · gene tree & orthology |
| Ubiquitin family | E3|E3 activity RING|PHD · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00856 all species → | SET | SET domain | Family | Interproscan |
| PF00855 all species → | PWWP | PWWP domain | Domain | Interproscan |
| PF17907 all species → | AWS | AWS domain | Domain | Interproscan |
| PF17982 all species → | C5HCH | NSD Cys-His rich domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR046341 all species → | Homologous_superfamily | SET domain superfamily | Interproscan |
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR019787 all species → | Domain | Zinc finger, PHD-finger | Interproscan |
| IPR001214 all species → | Domain | SET domain | Interproscan |
| IPR000313 all species → | Domain | PWWP domain | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR001965 all species → | Domain | Zinc finger, PHD-type | Interproscan |
| IPR019786 all species → | Conserved_site | Zinc finger, PHD-type, conserved site | Interproscan |
| IPR006560 all species → | Domain | AWS domain | Interproscan |
| IPR041306 all species → | Domain | NSD, Cys-His rich domain | Interproscan |
| IPR050777 all species → | Family | SET2 Histone-Lysine N-Methyltransferase | Interproscan |
| IPR003616 all species → | Domain | Post-SET domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22884 all species → | SET DOMAIN PROTEINS | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0042054 all species → | Molecular Function | histone methyltransferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11424 | WHSC1, MMSET, NSD2; [histone H3]-lysine36 N-dimethyltransferase NSD2 | EC:2.1.1.357 | Chromosome and associated proteins | ko03036 | deepkoala |
Genes whose expression across the transcriptome samples of Acropora pulchra tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Acropora pulchra, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |