Gene detail

Detailed information of FUN_025878-T1 in Acropora pulchra

Genomic Location: ptg000020l:1554061...1559100
NR annotation: XP_029190433.2, D-3-phosphoglycerate dehydrogenase-like [Acropora millepora]
Species abbreviation APULC · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q61753	D-3-phosphoglycerate dehydrogenase OS=Mus musculus OX=10090 GN=Phgdh PE=1 SV=3
Q5R7M2	D-3-phosphoglycerate dehydrogenase OS=Pongo abelii OX=9601 GN=PHGDH PE=2 SV=3
O43175	D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003616 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF19304 all species →	PGDH_inter	D-3-phosphoglycerate dehydrogenase intervening domain	Domain	Interproscan
PF00389 all species →	2-Hacid_dh	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Domain	Interproscan
PF02826 all species →	2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR045626 all species →	Domain	D-3-phosphoglycerate dehydrogenase, ASB domain	Interproscan
IPR006139 all species →	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Interproscan
IPR029753 all species →	Conserved_site	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site	Interproscan
IPR006140 all species →	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain	Interproscan
IPR006236 all species →	Family	D-3-phosphoglycerate dehydrogenase	Interproscan
IPR036291 all species →	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR029009 all species →	Homologous_superfamily	Allosteric substrate binding domain superfamily	Interproscan
IPR029752 all species →	Conserved_site	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42938 all species →	FORMATE DEHYDROGENASE 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016616 all species →	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0051287 all species →	Molecular Function	NAD binding	Interproscan
GO:0004617 all species →	Molecular Function	phosphoglycerate dehydrogenase activity	Interproscan
GO:0006564 all species →	Biological Process	L-serine biosynthetic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00058	serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase	EC:1.1.1.95 EC:1.1.1.399	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.