Genomic Location: contig_81:1041289...1047852
NR annotation: XP_020622832.1, biotin--protein ligase-like isoform X2 [Orbicella faveolata]
Species Dendrogyra cylindrus · all data for this species · gene families
| CDS |
| FUN_030671-T1 |
| Transcript |
| FUN_030671-T1 |
| Protein |
| FUN_030671-T1 |
| UniProt accession | Description |
|---|---|
| P50747 | Biotin--protein ligase OS=Homo sapiens OX=9606 GN=HLCS PE=1 SV=1 |
| Q920N2 | Biotin--protein ligase OS=Mus musculus OX=10090 GN=Hlcs PE=1 SV=1 |
| O14353 | Biotin--protein ligase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=bpl1 PE=3 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004470 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF09825 all species → | BPL_N | Biotin-protein ligase, N terminal | Domain | Interproscan |
| PF02237 all species → | BPL_C | Biotin protein ligase C terminal domain | Domain | Interproscan |
| PF03099 all species → | BPL_LplA_LipB | Biotin/lipoate A/B protein ligase family | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR045864 all species → | Homologous_superfamily | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | Interproscan |
| IPR029062 all species → | Homologous_superfamily | Class I glutamine amidotransferase-like | Interproscan |
| IPR004143 all species → | Domain | Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain | Interproscan |
| IPR019197 all species → | Domain | Biotin-protein ligase, N-terminal | Interproscan |
| IPR004408 all species → | Family | Biotin--acetyl-CoA-carboxylase ligase | Interproscan |
| IPR003142 all species → | Domain | Biotin protein ligase, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12835 all species → | BIOTIN PROTEIN LIGASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0036211 all species → | Biological Process | protein modification process | Interproscan |
| GO:0004077 all species → | Molecular Function | biotin--[biotin carboxyl-carrier protein] ligase activity | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K01942 | HLCS; biotin---protein ligase | EC:6.3.4.9 EC:6.3.4.10 EC:6.3.4.11 EC:6.3.4.15 | Biotin metabolism | ko00780 | deepkoala |
Genes whose expression across the transcriptome samples of Dendrogyra cylindrus tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Dendrogyra cylindrus, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
