Gene detail

Detailed information of FUN_033682-T2 in Dendrogyra cylindrus

Genomic Location: contig_106:745263...755982
NR annotation: XP_020619087.1, malate dehydrogenase, cytoplasmic-like [Orbicella faveolata]
Species abbreviation DCYLI · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

FUN_033682-T2

TTGCCCTTTTCTTATTCTATAAATCTCATCCTTTGATAAGATATTGTTATCGTTCATTCCTTCGACCTTTCTCGCTTTTTTACTCCTGACAACGCTGAGAATAGACCGGGAGAAGAGTAACGGAGCGAAACGAATCTTCGAAGGACTGAACAGGACTCAGGCTGATTGGTTCTTCACAGCTCAAAAAGCTGTTTACGATCTGTGCTGCACTATGGGATGTGTGTTTTGCCGGCGCCGttttgcagttttagtcttTCTAGCAGTTATAGATTTCCTCTTTCTTAGGGTTAAAAATTGGGCTTTCACGGAGGCATAAATTACTTTTCTTAAAGGGGCAGccaaaatttaaatttgtggCGCAGGAAACCTAAAATTAATTGGCCATTTTTATAAACAATTGCGATATTAGAGTGCTGAAACTGTtgacaagcgtctttggctgcggatggcttgaaTAGaagtggattacaacttgaaaaattaaggctaaactgcCTAAACTTTCAAGCGTGTTCAAAAATTTATAGAAACATTTTACACACGGCTTTCAAATCATTTCTAAACACGTGTGGTTTTCAACTCGTTTTTCATTGCGTTTCTAGACTCATTCACCTGACCAGAATTGGGCGTTCTGGTAGGCTGATAACAatatgaataattaatgagtttgagaagtgttTTTAGTGACTTTCATGTGACTCTATCGTGACAAGTCACGCCATAATACCCGTGGTTCCACAAGTTCGTGTCCAGGTCCAATACCATTCCTCTCGGCAAGTTGGTTCGTGTAGCGTGGCACGTTTTGTTCGAGAGCTGTCTCGTTGCATTTCTTTCGGACGTAATTTCCAGAACCATGGCAGAACCATTGCGTGTTTGTATCACCGGTGCTGCTGGACAGATTGCATACTCGCTTCTCTATTCCATTTGCAAAGGCGATGTGTTTGGATCTAATCAGCCACTGACCCTGCTGTTGCTGGATATTGAGCCTATGATGAGTGTTTTGGAAGGTGTCGTGATGGAATTGCAGGACTGTGCCTTTCCTTTGTTACAAGAGATTATTTCATCTGCTGACCCAAGGGTGGCATTCAAGGATATCGATGTAGCCATATTGGTTGGTGCCATGCCACGTAAGCAAGGAATGGAGAGGAAGGATCTTCTGAAAGCCAATGCCAAGATATTTGTTGAGCAAGGAAAAGCTCTGAATGAGGTGGCCAAGAAGACTGTCAAGGTTTTGGTAGTTGGTAATCCAGCAAACACAAACTGTATGGTTGCACACATGAATGCCCCATCCATTCCAGCTAAAAACTTTTCTTGTTTGACAAGATTAGATATGAACAGAGCCAAGGCACagATTGCTAGCAGACTTGGCATCCGAGTGGAACAAGTGAGAAATGTCATCATTTGGGGAAACCACTCATCTACTCAGTATCCAGATGTCGATCATGGCACGGTCGTGATGCCAGAGGGACATGTGCCCATTCGGCAGGCTGTCAAAGATGATGATTGGTTAAATGGTGATTTTGTTAAGACTGTTCAAAAGCGTGGTGCTGCCATCATTGCTGCCCGTAAGTTGTCCAGTGCCATGTCTGCTGCCAAAGCCATCTGTGATCACATGAGAGACTGGTGGTTTGGTACTCCTGAGGGTGAGTTGGTGTCCATGGGTGTGGTCTCCGATGGTTCTTATGGTGTACCACAAGGCATTGTGTACTCGTACCCAATGACCATAGCAAATTGGGAATGGAACATAAAGCAGGGTCTGAGCATTGATGACTTCTCGCGTGAGAAAATGGATGCCACCGCCAAGGAGCTTTTGGAGGAGAAAGAGAGTTGCCAATCATTCCTTGAATGACTAGCTTCGTCGCATCTATAGATGTCAGATCACAGTTCGTGTGTTGCGCATTTTAGGTCAGAGTGAAGCGTTGTATAACCGTGCAAGAGGCACTACTTGTATTTTATTGCAGTAAAGTGTAATTAAAATCAAGACAAGTTAAAACAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5ZME2	Malate dehydrogenase, cytoplasmic OS=Gallus gallus OX=9031 GN=MDH1 PE=2 SV=1
Q6DIY9	Malate dehydrogenase, cytoplasmic OS=Xenopus tropicalis OX=8364 GN=mdh1 PE=2 SV=1
Q6PAB3	Malate dehydrogenase, cytoplasmic OS=Xenopus laevis OX=8355 GN=mdh1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004875 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02866 all species →	Ldh_1_C	lactate/malate dehydrogenase, alpha/beta C-terminal domain	Domain	Interproscan
PF00056 all species →	Ldh_1_N	lactate/malate dehydrogenase, NAD binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011274 all species →	Family	Malate dehydrogenase, NAD-dependent, cytosolic	Interproscan
IPR001252 all species →	Active_site	Malate dehydrogenase, active site	Interproscan
IPR022383 all species →	Domain	Lactate/malate dehydrogenase, C-terminal	Interproscan
IPR010945 all species →	Family	Malate dehydrogenase, type 2	Interproscan
IPR001557 all species →	Family	L-lactate/malate dehydrogenase	Interproscan
IPR036291 all species →	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR015955 all species →	Homologous_superfamily	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal	Interproscan
IPR001236 all species →	Domain	Lactate/malate dehydrogenase, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23382 all species →	MALATE DEHYDROGENASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006108 all species →	Biological Process	malate metabolic process	Interproscan
GO:0030060 all species →	Molecular Function	L-malate dehydrogenase (NAD+) activity	Interproscan
GO:0016615 all species →	Molecular Function	malate dehydrogenase activity	Interproscan
GO:0016616 all species →	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006099 all species →	Biological Process	tricarboxylic acid cycle	Interproscan
GO:0006107 all species →	Biological Process	oxaloacetate metabolic process	Interproscan
GO:0006734 all species →	Biological Process	NADH metabolic process	Interproscan
GO:0019752 all species →	Biological Process	carboxylic acid metabolic process	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0016491 all species →	Molecular Function	oxidoreductase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00025	MDH1; malate dehydrogenase	EC:1.1.1.37	Proximal tubule bicarbonate reclamation	ko04964	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.