Genomic Location: ptg000027l:2735328...2760965
NR annotation: XP_029191825.2, tuberin-like isoform X4 [Acropora millepora]
Species abbreviation APULC · all data for this species · gene families
| CDS |
| FUN_038117-T1 |
| Transcript |
| FUN_038117-T1 |
| Protein |
| FUN_038117-T1 |
| UniProt accession | Description |
|---|---|
| P49815 | Tuberin OS=Homo sapiens OX=9606 GN=TSC2 PE=1 SV=2 |
| P49816 | Tuberin OS=Rattus norvegicus OX=10116 GN=Tsc2 PE=1 SV=1 |
| Q61037 | Tuberin OS=Mus musculus OX=10090 GN=Tsc2 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002253 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03542 all species → | Tuberin | Tuberin | Family | Interproscan |
| PF02145 all species → | Rap_GAP | Rap/ran-GAP | Family | Interproscan |
| PF11864 all species → | DUF3384 | Domain of unknown function (DUF3384) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011989 all species → | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR018515 all species → | Domain | Tuberin-type domain | Interproscan |
| IPR003913 all species → | Family | Tuberin | Interproscan |
| IPR016024 all species → | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR000331 all species → | Domain | Rap/Ran-GAP domain | Interproscan |
| IPR035974 all species → | Homologous_superfamily | Rap/Ran-GAP superfamily | Interproscan |
| IPR024584 all species → | Domain | Tuberin, N-terminal | Interproscan |
| IPR027107 all species → | Family | Tuberin/Ral GTPase-activating protein subunit alpha | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10063 all species → | TUBERIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005096 all species → | Molecular Function | GTPase activator activity | Interproscan |
| GO:0043547 all species → | Biological Process | positive regulation of GTPase activity | Interproscan |
| GO:0032007 all species → | Biological Process | negative regulation of TOR signaling | Interproscan |
| GO:0033596 all species → | Cellular Component | TSC1-TSC2 complex | Interproscan |
| GO:0051056 all species → | Biological Process | regulation of small GTPase mediated signal transduction | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0030178 all species → | Biological Process | negative regulation of Wnt signaling pathway | Interproscan |
| GO:0046627 all species → | Biological Process | negative regulation of insulin receptor signaling pathway | Interproscan |
| GO:0051726 all species → | Biological Process | regulation of cell cycle | Interproscan |
| GO:0051898 all species → | Biological Process | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K07207 | TSC2; tuberous sclerosis 2 | - | Protein phosphatases and associated proteins | ko01009 | deepkoala |