Gene detail

Detailed information of HK74SY85_g22234 in Paraphelliactis xishaensis sp. nov.

Genomic Location: ctg286:84224...89319
NR annotation: XP_020911885.1, histone-lysine N-methyltransferase EZH2 [Exaiptasia diaphana]
Species Paraphelliactis xishaensis sp. nov. · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

HK74SY85_g22234

ATGTGGTATCAACAAAATTCCTTTCAATTTTTCTTTTTAGTTTTTGATGAATACACACTGACAGACATTTTGTTAGTTGAGTTGATTGACAATGTCATGAAAACAATGGCTATCAAAGAGAGTGACATAAAACCTGCAGACACTGGTAAATAAACTATAATAATAATTTATTGAATGTCCATTTGTTTATTATATTTAAAAGTATGAATAATGTCTTAGAACTACAATGTACCTTGCTCAttggtaacgtgttagtaagtgggtgttaaagtgtcagtaagtggttggtaaggcgtcagtaagtggttggtaaggtgtcagtaagtggttggtaaggtgtcagtaagtggttggtaaggtgtcagtaagttgttgttaggtgtcagtaagtggttggtattgtgtcagtaagtggttggtaagctaggatcagtaagtggttggtaaggtgtccataagtgattggttaagatgtcagtaagtggttggtgaggtgtcagtaagtggttggtaaggtgtcagtaagtgattggtaaggtgtcagtaagtggttggtaaggtgtcagtaagtggttggtaaggtgtcagtaagtggttggtaaggtgtcagtaagtggttggtaaggtgtcaataagtggttggtaaggtgtcagtaagtggttggtaaggtgtcagtaagtggttggtaaggtgtcaataagtggttggtaaggtgtcagtaagtggttggtaaggtgtcaataagtggttggtaaggtgtcagtaagtggttggtaaggtgtgagtaagtggttggtaaggtgtcagtaagtggttggtaaggtgtcaataagtggttggtaaggtgtcagtaagtggttggtaaggtgtcagtaagtggttggtaaagtaacagtaaAATTCCTATATTATTGTCAGTTAAAGAGTCTAACGATGAACCCCCAGTACCCATGGAAACAGAAGCAGATAATAACAACACAACAGAAGAGAAAAAAGAAGACATAAAGAGTATAGGCACGCAACCCTCACCACCTTCTGAAGTGTTTCAAACAATTGCTAACATGTTTCCAGAGAAGTCATGGACTGAAGATGATATCAAAAACAGGTAAGTATTTGTCACATAGATTTTGAATATGTGattattatccttcttaatgataatcatgattatttcatgattattttatgattattcatgattatCCGAGAATTGTAGGCTTAGTGGAAAAAGGGCTAAATCTTCTTGAAATGACTGAAAATCATGAATCTATGCTGTCCTTTACACAATGACACAATGTGAATGTTTTTATTAACAAAAAGTTCACCTTTAGACAGTGTAAAAGtgtattgtacatgtacatatgtatgtagtatatttatatATTGCATTGTTTGTACTTTTTATTCAAATACAGGTATTTTGAGGAGGTTAATCGTAAAAAGGGTTTACTACCCCCGGAATGCACCCCTAACATTGACAGGTCAGTAGATCGAAACATTGCATTATCAGTGACAGCTGAGATTTTGCTGGACTCTAAGTTGAAAATCTTGATAAGATCATCAACCAAGATGAACCCTAAGTGTGTCCCCCTAGACTTCATTATAAAAATAattacttgaatattgattatattaatttattattactaattagattaaaacaaagtttataatattCAAATCAAGATTCATTTCCAAATTCGAATTCTGATTGGATTAATGGCCAAGACAGACGGCAAAGTAATTGCATAGAAGATTACTGTATCTTGAAGAAGAAACCTTCCTGTATCTCAGAACCATAAATACTGTGTTTCTGAAGCTTCCATATCTCCATACAATATAAACACTGTCTGTTATTTTTCTATCCAACCTTAAGTGAATGGAGTCACAGTACCATATGCTATCATAAATCGAATGTTGAAATCTGAGTTTTAGTTTGGAAAGTTTGGAAGTTTCAATTGCAATATTGAATTTAAGTTCTAAAAAATAAAAGTGAATAATGAAGTCTAGGGGGGGGGGGGGGGGCATGCTTGACATGGTTTGATTGTAAGTAATGGTTTTTCAATCATACAAACTCTGCTTTGTTGTAATTAAATGCTATACCTTGCAACTCTCACTATGCCAGACAGAAGTGTATAGACATCAACATCTCTGTTCATCTTTTTTAGTCATCAAGCACAATCAGTGTCTAGAGAACAAAGTCTACATTCCTTTCACATGCTGTTTTGCCGTAGATGTTACAAATATGATTGCTTTATGCATGGTATGTAGTTCATATTTGATCATCTGatatatagaaactagcaagtaaactagtagtatgggctgtgttggtaaatgatgatataaggatggttgaatggaaactagcaagtaaactagtatgggctgcgttggtgtatgatgatacaaggatggataaatggaaactagctagtaaactagtagtatgggctgtgttggtgaatgatgatataaggatggttgaatggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaatggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaatggaaactagctagtaaactagtagtatgggctgtgttggtgaatgatgatataaggatggttgaatagaaactagttagtaaactagtagtatgggctgtgttggtaaatgatgatataaggttggttgaatggaaactagctagtaaactagtactatgggctgtgttggtaaatgatgatataaggatggttgaatggaaactagcaagtaaactagtagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagctagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagcaagtaaactagtatgggctgtgttggtgaatgatgatataaggatggttgaaaggaaactagcaagtaaactagtatgggctgtgttggtaaatgatgatataaggatggttgaatggaaactagcaagtaaactagtatgggctgtgttggtaaatgatgatataaggatggttgaatggaaactagcaagtaaactagtagtatgggctgtgttggtaaatgatgatataaggatggttgaatggaaactagcaagtaaactagtagtatgggctgtgttggtaaatgatgatataaggatggttgaatggaaactagcaagtaaactagtatgggctgtgttggtaaatgatgatataaggatggttgaatggaaactagcaagtaaactagtagtatgggctgtgttggtaaatgatgatataaggattggtaaaGttagatttagatttagatttagatttatttccatttacaccaccttttacaatattactatacaaatcagtaattacagcagttaggtgttaggatacctgaaaatagtttgtggactaatcagagtcaggtaccctagtacaatgaaaggaaattaaaaatatctctgaattttagtcataatatatttacctaaattatttaaattaaatcatatttatctaaatttatatactgaatacaataaatggcaataaatggtttataaatatgtaaatagaatagaaaaaaaggaaatctttaacaccgtgtaaaaatagtgacttactttactgatgttagagcagatttcgtaagagtgggaagtggttatggtagtcgtgaccatgatggtactgtaaccaagcattctgattggatgagcagtgatttgtgcactgtgattggttgaatagatgctgttgattcctaatggtgaccgtaggtttcccactcatacgaaaacgactctaTgagccttagcccttcgtcggagtatacgttactctgatatgatggacttgaaatgtcagtgttaatagtttgtcagcatgctatttttacacagtgttacagatttccttttacccatcctttgattatcTGAGATAATTATTTAAAAATTGTATATATTTTGCCAATCTCGCAGGCTGGAAACCACTGCCGAATCTAACAAAGAGAAAGGTAAGGTATGACTGTAGGGCATATACAATTATCTTGTCGTCAAACTAAATCTTGTCGTGTAACTTCCTCAGAGCCCTGTTGACTTACAAGAAGCATCACCTTGTGGAACAGACTGTTACATGCATATCAAGGTCTGGTTTTATTTAACTCTGTCTGATTATTAATACTTCATTTTAGCATTGAAAGGATAGTCTgagtgcaaatattatatctgtgaaatagttaactatctgaaaacatgtagtactaaatagcataaaatgttttattttcaagtttaattagaagtgctatttagcactaattagttagtactgtttcatggattaagtgtgagcactctagtttaccttAAATTGCGTTTTCTTGATATATGTTATCTTTATTTGATGTCTAGAGTACTAATGGGAGTCCTGTGAACTCTCCTGGCAAACCTGAAACTACAACAAGAAAACGCAATAGAGGAAAAAATAGAACAGGATCTCAACAACAGAGTGGAACTACTCAAGACATATCAAGTGTAGGTGTTGTTCATTGGGGTAAAAGTAAAGGTTTATTCTCTAATGGCATGACTTTGTTCAATGTTACACAAAAGAACTATTTTTGTGACGCTGTTCAAACTACAGTATACAGCAAACTATACTCTGTTCCAGACCAAATCATTATGTGGTATCAACAAAATTCCTTTCAATTTTTCTTTTTAGTTTTTGATGAATACACACTGACAGACATTTTGTTAGTTGAGTTGATTGACAATGTCATGAAAACAATGGCTATCAAAGAGAGTGACATAAAACCTGCAGACACTGTTAAAGAGTCTAACGATGAACCCCCAGTACCCATGGAAACAGAAGCAGATAATAACAACACAACAGAAGAGAAAAAAGAAGACATAAAGAGTATAGGCACGCAACCCTCACCACCTTCTGAAGTGTTTCAAACAATTGCTAACATGTTTCCAGAGAAGTCATGGACTGAAGATGATATCAAAAACAGATACAGGTATTTTGAGGAGGTTAATCGTAAAAAGGGTTTACTACCCCCGGAATGCACCCCTAACATTGACAGTCATCAAGCACAATCAGTGTCTAGAGAACAAAGTCTACATTCCTTTCACATGCTGTTTTGCCGTAGATGTTACAAATATGATTGCTTTATGCATGGCTGGAAACCACTGCCGAATCTAACAAAGAGAAAGAGCCCTGTTGACTTACAAGAAGCATCACCTTGTGGAACAGACTGTTACATGCATATCAAGAGTACTAATGGGAGTCCTGTGAACTCTCCTGGCAAACCTGAAACTACAACAAGAAAACGCAATAGAGGAAAAAATAGAACAGGATCTCAACAACAGAGTGGAACTACTCAAGACATATCAAGTGTAGGTGTTGTTCATTGGGGTAAAAGTAAAGGTTTATTCTCTAATGGCATGACTTTGTTCAATGTTACACAAAAGAACTATTTTTGTGACGCTGTTCAAACTACAGTATACAGCAAACTATACTCTGTTCCAGACCAAATCATT

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q08BS4	Histone-lysine N-methyltransferase EZH2 OS=Danio rerio OX=7955 GN=ezh2 PE=2 SV=1
Q15910	Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2
Q4R381	Histone-lysine N-methyltransferase EZH2 OS=Macaca fascicularis OX=9541 GN=EZH2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004254 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF21358 all species →	Ezh2_MCSS	Ezh2, MCSS domain	Domain	Interproscan
PF18118 all species →	PRC2_HTH_1	Polycomb repressive complex 2 tri-helical domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR048358 all species →	Domain	EZH1/2, MCSS domain	Interproscan
IPR045318 all species →	Family	Histone-lysine N-methyltransferase EZH1/2-like	Interproscan
IPR041343 all species →	Domain	Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45747 all species →	HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003682 all species →	Molecular Function	chromatin binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0006338 all species →	Biological Process	chromatin remodeling	Interproscan
GO:0031507 all species →	Biological Process	heterochromatin formation	Interproscan
GO:0035098 all species →	Cellular Component	ESC/E(Z) complex	Interproscan
GO:0042054 all species →	Molecular Function	histone methyltransferase activity	Interproscan
GO:0046976 all species →	Molecular Function	histone H3K27 methyltransferase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for HK74SY85_g22234.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Paraphelliactis xishaensis sp. nov. tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paraphelliactis xishaensis sp. nov., and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →