Genomic Location: ctg387:473108...483736
NR annotation: XP_020896365.1, folliculin [Exaiptasia diaphana]
Species abbreviation PXISH · all data for this species · gene families
| CDS |
| HK74SY85_g25034 |
| Transcript |
| HK74SY85_g25034 |
| Protein |
| HK74SY85_g25034 |
| UniProt accession | Description |
|---|---|
| Q8NFG4 | Folliculin OS=Homo sapiens OX=9606 GN=FLCN PE=1 SV=1 |
| Q8QZS3 | Folliculin OS=Mus musculus OX=10090 GN=Flcn PE=1 SV=1 |
| Q5M7Q1 | Folliculin OS=Xenopus tropicalis OX=8364 GN=flcn PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005183 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF16692 all species → | Folliculin_C | Folliculin C-terminal domain | Domain | Interproscan |
| PF11704 all species → | Folliculin | Vesicle coat protein involved in Golgi to plasma membrane transport | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR021713 all species → | Family | Folliculin | Interproscan |
| IPR044886 all species → | Homologous_superfamily | Folliculin, DENN domain, C-terminal superfamily | Interproscan |
| IPR032035 all species → | Domain | Folliculin, DENN domain | Interproscan |
| IPR037520 all species → | Domain | Folliculin/SMCR8, longin domain | Interproscan |
| IPR037521 all species → | Domain | Folliculin/SMCR8, tripartite DENN domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR31441 all species → | FOLLICULIN FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000122 all species → | Biological Process | negative regulation of transcription by RNA polymerase II | Interproscan |
| GO:0005096 all species → | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0030511 all species → | Biological Process | positive regulation of transforming growth factor beta receptor signaling pathway | Interproscan |
| GO:1904263 all species → | Biological Process | positive regulation of TORC1 signaling | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09594 | FLCN, BHD; folliculin | - | Renal cell carcinoma | ko05211 | deepkoala |