Gene detail

Detailed information of HOLI00001.G49300 in Hydra oligactis

Genomic Location: HOLI00001:343838...345313
NR annotation: WP_065761832.1, MULTISPECIES: bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD [Pseudomonas]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

Protein

Uniprot

Uniprot term	Description
Q1ICB3	Bifunctional protein FolD OS=Pseudomonas entomophila (strain L48) OX=384676 GN=folD PE=3 SV=1
Q88KM5	Bifunctional protein FolD 2 OS=Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) OX=160488 GN=folD2 PE=3 SV=1
A5W638	Bifunctional protein FolD OS=Pseudomonas putida (strain ATCC 700007 / DSM 6899 / JCM 31910 / BCRC 17059 / LMG 24140 / F1) OX=351746 GN=folD PE=3 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02882	THF_DHG_CYH_C	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	Domain	Interproscan
PF00763	THF_DHG_CYH	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000672	Family	Tetrahydrofolate dehydrogenase/cyclohydrolase	Interproscan
IPR020631	Domain	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	Interproscan
IPR046346	Homologous_superfamily	Aminoacid dehydrogenase-like, N-terminal domain superfamily	Interproscan
IPR020630	Domain	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	Interproscan
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR48099	C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004488	Molecular Function	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Interproscan
GO:0004477	Molecular Function	methenyltetrahydrofolate cyclohydrolase activity	Interproscan
GO:0005829	Cellular Component	cytosol	Interproscan
GO:0035999	Biological Process	tetrahydrofolate interconversion	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01491	folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase	EC:1.5.1.5 EC:3.5.4.9	One carbon pool by folate	ko00670	deepkoala