Gene detail

Detailed information of HOLI00001.G49587 in Hydra oligactis

Genomic Location: HOLI00001:693579...694478
NR annotation: WP_110972262.1, hydroxymethylglutaryl-CoA lyase [Pseudomonas huaxiensis]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q9I2A0	3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=liuE PE=1 SV=1
P13703	Hydroxymethylglutaryl-CoA lyase OS=Pseudomonas mevalonii OX=32044 GN=mvaB PE=3 SV=1
Q8HXZ6	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Macaca fascicularis OX=9541 GN=HMGCL PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00682	HMGL-like	HMGL-like	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR043594	Family	HMG-CoA lyase	Interproscan
IPR000891	Domain	Pyruvate carboxyltransferase	Interproscan
IPR000138	Active_site	Hydroxymethylglutaryl-CoA lyase, active site	Interproscan
IPR013785	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42738	HYDROXYMETHYLGLUTARYL-COA LYASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004419	Molecular Function	hydroxymethylglutaryl-CoA lyase activity	Interproscan
GO:0006552	Biological Process	L-leucine catabolic process	Interproscan
GO:0016833	Molecular Function	oxo-acid-lyase activity	Interproscan
GO:0046951	Biological Process	ketone body biosynthetic process	Interproscan
GO:0003824	Molecular Function	catalytic activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01640	HMGCL, hmgL; hydroxymethylglutaryl-CoA lyase	EC:4.1.3.4	Peroxisome	ko04146	deepkoala