Genomic Location: HOLI00001:4595463...4595909
NR annotation: WP_175652669.1, dihydrofolate reductase [Pseudomonas sp. Marseille-P9899]
| CDS | |||||
| HOLI00001.g52615.t1 | |||||
| Transcript |
| HOLI00001.g52615.t1 |
| Protein |
| HOLI00001.G52615 |
| Uniprot term | Description |
|---|---|
| P12833 | Dihydrofolate reductase type 3 OS=Salmonella typhimurium OX=90371 GN=dhfrIII PE=1 SV=1 |
| P11045 | Dihydrofolate reductase OS=Bacillus subtilis (strain 168) OX=224308 GN=dfrA PE=1 SV=2 |
| P04174 | Dihydrofolate reductase OS=Neisseria gonorrhoeae OX=485 GN=folA PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00186 | DHFR_1 | Dihydrofolate reductase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR012259 | Family | Dihydrofolate reductase | Interproscan |
| IPR001796 | Domain | Dihydrofolate reductase domain | Interproscan |
| IPR024072 | Homologous_superfamily | Dihydrofolate reductase-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR48069 | DIHYDROFOLATE REDUCTASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004146 | Molecular Function | dihydrofolate reductase activity | Interproscan |
| GO:0046654 | Biological Process | tetrahydrofolate biosynthetic process | Interproscan |
| GO:0050661 | Molecular Function | NADP binding | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0046452 | Biological Process | dihydrofolate metabolic process | Interproscan |
| GO:0046655 | Biological Process | folic acid metabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00287 | DHFR, folA; dihydrofolate reductase | EC:1.5.1.3 | Antifolate resistance | ko01523 | deepkoala |