Gene detail

Detailed information of HOLI00001.G53463 in Hydra oligactis

Genomic Location: HOLI00001:5673878...5674765
NR annotation: WP_110971015.1, MULTISPECIES: 3-hydroxyisobutyrate dehydrogenase [Pseudomonas]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q54CX6	Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Dictyostelium discoideum OX=44689 GN=hibA PE=3 SV=1
Q9I5I6	NAD-dependent L-serine dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=PA0743 PE=1 SV=1
Q5R5E7	3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Pongo abelii OX=9601 GN=HIBADH PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF14833	NAD_binding_11	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	Domain	Interproscan
PF03446	NAD_binding_2	NAD binding domain of 6-phosphogluconate dehydrogenase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011548	Family	3-hydroxyisobutyrate dehydrogenase	Interproscan
IPR002204	Conserved_site	3-hydroxyisobutyrate dehydrogenase-related, conserved site	Interproscan
IPR008927	Homologous_superfamily	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily	Interproscan
IPR013328	Homologous_superfamily	6-phosphogluconate dehydrogenase, domain 2	Interproscan
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR029154	Domain	3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain	Interproscan
IPR006115	Domain	6-phosphogluconate dehydrogenase, NADP-binding	Interproscan
IPR015815	Family	3-hydroxyisobutyrate dehydrogenase-related	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22981	3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0016616	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0008442	Molecular Function	3-hydroxyisobutyrate dehydrogenase activity	Interproscan
GO:0051287	Molecular Function	NAD binding	Interproscan
GO:0016491	Molecular Function	oxidoreductase activity	Interproscan
GO:0050661	Molecular Function	NADP binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00020	HIBADH, mmsB; 3-hydroxyisobutyrate dehydrogenase	EC:1.1.1.31	Valine, leucine and isoleucine degradation	ko00280	deepkoala