Genomic Location: HOLI00002:2584014...2585051
NR annotation: MCD6020132.1, dihydroorotate dehydrogenase [Bacteroidota bacterium]
| CDS | |||||
| HOLI00002.g19448.t1 | |||||
| Transcript |
| HOLI00002.g19448.t1 |
| Protein |
| HOLI00002.G19448 |
| Uniprot term | Description |
|---|---|
| A0M4D0 | Dihydroorotate dehydrogenase (quinone) OS=Christiangramia forsetii (strain DSM 17595 / CGMCC 1.15422 / KT0803) OX=411154 GN=pyrD PE=3 SV=1 |
| A6H0L5 | Dihydroorotate dehydrogenase (quinone) OS=Flavobacterium psychrophilum (strain ATCC 49511 / DSM 21280 / CIP 103535 / JIP02/86) OX=402612 GN=pyrD PE=3 SV=1 |
| A5FHT2 | Dihydroorotate dehydrogenase (quinone) OS=Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / BCRC 14874 / CCUG 350202 / NBRC 14942 / NCIMB 11054 / UW101) OX=376686 GN=pyrD PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01180 | DHO_dh | Dihydroorotate dehydrogenase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001295 | Conserved_site | Dihydroorotate dehydrogenase, conserved site | Interproscan |
| IPR005719 | Family | Dihydroorotate dehydrogenase, class 2 | Interproscan |
| IPR012135 | Family | Dihydroorotate dehydrogenase, class 1/ 2 | Interproscan |
| IPR013785 | Homologous_superfamily | Aldolase-type TIM barrel | Interproscan |
| IPR050074 | Family | Dihydroorotate dehydrogenase | Interproscan |
| IPR005720 | Domain | Dihydroorotate dehydrogenase, catalytic | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR48109 | DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0006207 | Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | Interproscan |
| GO:0016627 | Molecular Function | oxidoreductase activity, acting on the CH-CH group of donors | Interproscan |
| GO:0004152 | Molecular Function | dihydroorotate dehydrogenase activity | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0006222 | Biological Process | UMP biosynthetic process | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0009220 | Biological Process | pyrimidine ribonucleotide biosynthetic process | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00254 | DHODH, pyrD; dihydroorotate dehydrogenase | EC:1.3.5.2 | Pyrimidine metabolism | ko00240 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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