Genomic Location: HOLI00002:2799900...2801086
NR annotation: MBI3518649.1, 3'-5' exonuclease [Bacteroidota bacterium]
| CDS | ||||
| HOLI00002.g19637.t1 | ||||
| Transcript |
| HOLI00002.g19637.t1 |
| Protein |
| HOLI00002.G19637 |
| Uniprot term | Description |
|---|---|
| P43791 | Dihydrofolate reductase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=folA PE=3 SV=1 |
| P12833 | Dihydrofolate reductase type 3 OS=Salmonella typhimurium OX=90371 GN=dhfrIII PE=1 SV=1 |
| P11045 | Dihydrofolate reductase OS=Bacillus subtilis (strain 168) OX=224308 GN=dfrA PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00186 | DHFR_1 | Dihydrofolate reductase | Domain | Interproscan |
| PF10108 | DNA_pol_B_exo2 | Predicted 3'-5' exonuclease related to the exonuclease domain of PolB | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036397 | Homologous_superfamily | Ribonuclease H superfamily | Interproscan |
| IPR001796 | Domain | Dihydrofolate reductase domain | Interproscan |
| IPR017925 | Conserved_site | Dihydrofolate reductase conserved site | Interproscan |
| IPR019288 | Domain | Predicted 3'-5' exonuclease, PolB-like | Interproscan |
| IPR012259 | Family | Dihydrofolate reductase | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR024072 | Homologous_superfamily | Dihydrofolate reductase-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR48069 | DIHYDROFOLATE REDUCTASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003676 | Molecular Function | nucleic acid binding | Interproscan |
| GO:0004146 | Molecular Function | dihydrofolate reductase activity | Interproscan |
| GO:0046654 | Biological Process | tetrahydrofolate biosynthetic process | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0046452 | Biological Process | dihydrofolate metabolic process | Interproscan |
| GO:0046655 | Biological Process | folic acid metabolic process | Interproscan |
| GO:0050661 | Molecular Function | NADP binding | Interproscan |