Gene detail

Detailed information of HOLI00002.G20422 in Hydra oligactis

Genomic Location: HOLI00002:3767640...3768590
NR annotation: MBI3518854.1, 2-hydroxyacid dehydrogenase [Bacteroidota bacterium]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
P44501	2-hydroxyacid dehydrogenase homolog OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=ddh PE=3 SV=1
P30799	2-hydroxyacid dehydrogenase homolog OS=Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) OX=264203 GN=ddh PE=3 SV=3
Q2UH56	2-hydroxyacid dehydrogenase A OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=AO090023000577 PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00389	2-Hacid_dh	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Domain	Interproscan
PF02826	2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR006139	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Interproscan
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR029752	Conserved_site	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1	Interproscan
IPR029753	Conserved_site	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site	Interproscan
IPR006140	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43026	2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0016616	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan
GO:0051287	Molecular Function	NAD binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K03778	ldhA; D-lactate dehydrogenase	EC:1.1.1.28	Pyruvate metabolism	ko00620	deepkoala