Gene detail

Detailed information of HOLI00002.G21375 in Hydra oligactis

Genomic Location: HOLI00002:4895648...4896835
NR annotation: MBI3520469.1, bifunctional folylpolyglutamate synthase/dihydrofolate synthase [Bacteroidota bacterium]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

Protein

Uniprot

Uniprot term	Description
Q05865	Dihydrofolate synthase/folylpolyglutamate synthase OS=Bacillus subtilis (strain 168) OX=224308 GN=folC PE=3 SV=2
D4GW05	Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) OX=309800 GN=folCP PE=3 SV=1
P15925	Folylpolyglutamate synthase OS=Lacticaseibacillus casei OX=1582 GN=fpgS PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08245	Mur_ligase_M	Mur ligase middle domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR018109	Conserved_site	Folylpolyglutamate synthetase, conserved site	Interproscan
IPR001645	Family	Folylpolyglutamate synthetase	Interproscan
IPR036565	Homologous_superfamily	Mur-like, catalytic domain superfamily	Interproscan
IPR036615	Homologous_superfamily	Mur ligase, C-terminal domain superfamily	Interproscan
IPR013221	Domain	Mur ligase, central	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11136	FOLYLPOLYGLUTAMATE SYNTHASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004326	Molecular Function	tetrahydrofolylpolyglutamate synthase activity	Interproscan
GO:0005524	Molecular Function	ATP binding	Interproscan
GO:0009396	Biological Process	folic acid-containing compound biosynthetic process	Interproscan
GO:0009058	Biological Process	biosynthetic process	Interproscan
GO:0016881	Molecular Function	acid-amino acid ligase activity	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan
GO:0008841	Molecular Function	dihydrofolate synthase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K11754	folC; dihydrofolate synthase / folylpolyglutamate synthase	EC:6.3.2.12 EC:6.3.2.17	Folate biosynthesis	ko00790	deepkoala