Gene detail

Detailed information of HOLI00059.G25562 in Hydra oligactis

Genomic Location: HOLI00059:48808...49716
NR annotation: WP_105261359.1, hydroxymethylglutaryl-CoA lyase [Rhodoferax sp. TS-BS-61-7]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q29448	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Bos taurus OX=9913 GN=HMGCL PE=2 SV=2
P97519	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Hmgcl PE=2 SV=1
P38060	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Mus musculus OX=10090 GN=Hmgcl PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00682	HMGL-like	HMGL-like	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR013785	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan
IPR043594	Family	HMG-CoA lyase	Interproscan
IPR000891	Domain	Pyruvate carboxyltransferase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR42738	HYDROXYMETHYLGLUTARYL-COA LYASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004419	Molecular Function	hydroxymethylglutaryl-CoA lyase activity	Interproscan
GO:0006552	Biological Process	L-leucine catabolic process	Interproscan
GO:0016833	Molecular Function	oxo-acid-lyase activity	Interproscan
GO:0046951	Biological Process	ketone body biosynthetic process	Interproscan
GO:0003824	Molecular Function	catalytic activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01640	HMGCL, hmgL; hydroxymethylglutaryl-CoA lyase	EC:4.1.3.4	Peroxisome	ko04146	deepkoala