Genomic Location: HOLI00059:976974...978335
NR annotation: WP_105259777.1, thymidylate synthase [Rhodoferax sp. TS-BS-61-7]
| CDS | ||||
| HOLI00059.g26393.t1 | ||||
| Transcript |
| HOLI00059.g26393.t1 |
| Protein |
| HOLI00059.G26393 |
| Uniprot term | Description |
|---|---|
| Q12CI6 | Thymidylate synthase OS=Polaromonas sp. (strain JS666 / ATCC BAA-500) OX=296591 GN=thyA PE=3 SV=1 |
| A1TM53 | Thymidylate synthase OS=Paracidovorax citrulli (strain AAC00-1) OX=397945 GN=thyA PE=3 SV=1 |
| Q21U56 | Thymidylate synthase OS=Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) OX=338969 GN=thyA PE=3 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00186 | DHFR_1 | Dihydrofolate reductase | Domain | Interproscan |
| PF00303 | Thymidylat_synt | Thymidylate synthase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001796 | Domain | Dihydrofolate reductase domain | Interproscan |
| IPR036926 | Homologous_superfamily | Thymidylate synthase/dCMP hydroxymethylase superfamily | Interproscan |
| IPR023451 | Domain | Thymidylate synthase/dCMP hydroxymethylase domain | Interproscan |
| IPR000398 | Family | Thymidylate synthase | Interproscan |
| IPR045097 | Family | Thymidylate synthase/dCMP hydroxymethylase | Interproscan |
| IPR020940 | Active_site | Thymidylate synthase, active site | Interproscan |
| IPR017925 | Conserved_site | Dihydrofolate reductase conserved site | Interproscan |
| IPR024072 | Homologous_superfamily | Dihydrofolate reductase-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11548 | THYMIDYLATE SYNTHASE 1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004146 | Molecular Function | dihydrofolate reductase activity | Interproscan |
| GO:0046654 | Biological Process | tetrahydrofolate biosynthetic process | Interproscan |
| GO:0004799 | Molecular Function | thymidylate synthase activity | Interproscan |
| GO:0006231 | Biological Process | dTMP biosynthetic process | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0016741 | Molecular Function | transferase activity, transferring one-carbon groups | Interproscan |