Genomic Location: HOLI00197:308787...362752
NR annotation: XP_047128191.1, pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Hydra vulgaris]
| CDS | ||||
| HOLI00197.g7855.t1 | ||||
| Transcript |
| HOLI00197.g7855.t1 |
| Protein |
| HOLI00197.G7855 |
| Uniprot term | Description |
|---|---|
| P52900 | Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial (Fragment) OS=Sminthopsis macroura OX=9302 GN=PDHA PE=2 SV=1 |
| P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3 |
| P26267 | Pyruvate dehydrogenase E1 component subunit alpha type I, mitochondrial OS=Ascaris suum OX=6253 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00255 | GSHPx | Glutathione peroxidase | Family | Interproscan |
| PF00676 | E1_dh | Dehydrogenase E1 component | Family | Interproscan |
| PF00108 | Thiolase_N | Thiolase, N-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029061 | Homologous_superfamily | Thiamin diphosphate-binding fold | Interproscan |
| IPR017597 | Family | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y | Interproscan |
| IPR000889 | Family | Glutathione peroxidase | Interproscan |
| IPR036249 | Homologous_superfamily | Thioredoxin-like superfamily | Interproscan |
| IPR016039 | Homologous_superfamily | Thiolase-like | Interproscan |
| IPR001017 | Domain | Dehydrogenase, E1 component | Interproscan |
| IPR050642 | Family | Pyruvate Dehydrogenase E1 Alpha Subunit | Interproscan |
| IPR020616 | Domain | Thiolase, N-terminal | Interproscan |
| IPR029760 | Conserved_site | Glutathione peroxidase conserved site | Interproscan |
| IPR020615 | Active_site | Thiolase, acyl-enzyme intermediate active site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11516 | PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004739 | Molecular Function | pyruvate dehydrogenase (acetyl-transferring) activity | Interproscan |
| GO:0006086 | Biological Process | acetyl-CoA biosynthetic process from pyruvate | Interproscan |
| GO:0043231 | Cellular Component | intracellular membrane-bounded organelle | Interproscan |
| GO:0004601 | Molecular Function | peroxidase activity | Interproscan |
| GO:0006979 | Biological Process | response to oxidative stress | Interproscan |
| GO:0016746 | Molecular Function | acyltransferase activity | Interproscan |
| GO:0016624 | Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Interproscan |
| GO:0016747 | Molecular Function | acyltransferase activity, transferring groups other than amino-acyl groups | Interproscan |