Gene detail

Detailed information of HOLI00256.G40429 in Hydra oligactis

Genomic Location: HOLI00256:101556...103041
NR annotation: WP_245612916.1, hydroxymethylbilane synthase [Pararheinheimera texasensis]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q48AW8	Porphobilinogen deaminase OS=Colwellia psychrerythraea (strain 34H / ATCC BAA-681) OX=167879 GN=hemC PE=3 SV=1
Q088L3	Porphobilinogen deaminase OS=Shewanella frigidimarina (strain NCIMB 400) OX=318167 GN=hemC PE=3 SV=1
B0TJ54	Porphobilinogen deaminase OS=Shewanella halifaxensis (strain HAW-EB4) OX=458817 GN=hemC PE=3 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01379	Porphobil_deam	Porphobilinogen deaminase, dipyromethane cofactor binding domain	Domain	Interproscan
PF03900	Porphobil_deamC	Porphobilinogen deaminase, C-terminal domain	Domain	Interproscan
PF02602	HEM4	Uroporphyrinogen-III synthase HemD	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR022417	Domain	Porphobilinogen deaminase, N-terminal	Interproscan
IPR000860	Family	Porphobilinogen deaminase	Interproscan
IPR022418	Domain	Porphobilinogen deaminase, C-terminal	Interproscan
IPR036803	Homologous_superfamily	Porphobilinogen deaminase, C-terminal domain superfamily	Interproscan
IPR003754	Domain	Tetrapyrrole biosynthesis, uroporphyrinogen III synthase	Interproscan
IPR036108	Homologous_superfamily	Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily	Interproscan
IPR022419	Binding_site	Porphobilinogen deaminase, dipyrromethane cofactor binding site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11557	PORPHOBILINOGEN DEAMINASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004418	Molecular Function	hydroxymethylbilane synthase activity	Interproscan
GO:0033014	Biological Process	tetrapyrrole biosynthetic process	Interproscan
GO:0005737	Cellular Component	cytoplasm	Interproscan
GO:0006783	Biological Process	heme biosynthetic process	Interproscan
GO:0004852	Molecular Function	uroporphyrinogen-III synthase activity	Interproscan
GO:0018160	Biological Process	peptidyl-pyrromethane cofactor linkage	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K01749	hemC, HMBS; hydroxymethylbilane synthase	EC:2.5.1.61	Porphyrin metabolism	ko00860	deepkoala