Detailed information of HOLI00469.G13420 in Hydra oligactis

Genomic Location: HOLI00469:99007...163070
NR annotation: XP_047139254.1, eIF-2-alpha kinase GCN2-like isoform X1 [Hydra vulgaris]


 Gene Structure
More details in Jbrowse  Sequence
CDS
Transcript
Protein
 Uniprot
Uniprot termDescription
D4A7V9eIF-2-alpha kinase GCN2 OS=Rattus norvegicus OX=10116 GN=Eif2ak4 PE=3 SV=2
Q9QZ05eIF-2-alpha kinase GCN2 OS=Mus musculus OX=10090 GN=Eif2ak4 PE=1 SV=2
Q9P2K8eIF-2-alpha kinase GCN2 OS=Homo sapiens OX=9606 GN=EIF2AK4 PE=1 SV=3

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00069PkinaseProtein kinase domainDomainInterproscan
PF05773RWDRWD domainDomainInterproscan
PF13393tRNA-synt_HisHistidyl-tRNA synthetaseDomainInterproscan
PF12745HGTP_anticodon2Anticodon binding domain of tRNAsDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR050339FamilyCell Cycle and Stress Response KinaseInterproscan
IPR016135Homologous_superfamilyUbiquitin-conjugating enzyme/RWD-likeInterproscan
IPR000719DomainProtein kinase domainInterproscan
IPR006575DomainRWD domainInterproscan
IPR008271Active_siteSerine/threonine-protein kinase, active siteInterproscan
IPR011009Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan
IPR041715DomainClass II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domainInterproscan
IPR016255FamilyeIF-2-alpha kinase Gcn2Interproscan
IPR017441Binding_siteProtein kinase, ATP binding siteInterproscan
IPR024435DomainHistidyl tRNA synthetase-related domainInterproscan
IPR045864Homologous_superfamilyClass II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11042EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATEDInterproscan

 Gene Ontology
GO termsCategoryDescriptionSource
GO:0004672Molecular Functionprotein kinase activityInterproscan
GO:0004694Molecular Functioneukaryotic translation initiation factor 2alpha kinase activityInterproscan
GO:0005634Cellular ComponentnucleusInterproscan
GO:0005737Cellular ComponentcytoplasmInterproscan
GO:0005829Cellular ComponentcytosolInterproscan
GO:0006468Biological Processprotein phosphorylationInterproscan
GO:0010998Biological Processregulation of translational initiation by eIF2 alpha phosphorylationInterproscan
GO:1990625Biological Processnegative regulation of cytoplasmic translational initiation in response to stressInterproscan
GO:0005524Molecular FunctionATP bindingInterproscan
GO:0005515Molecular Functionprotein bindingInterproscan
GO:0000077Biological ProcessDNA damage checkpoint signalingInterproscan

 KEGG pathway
KOEnzymeEnzyme IDpathwaymapIDSource
K16196EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4EC:2.7.11.1
Protein kinasesko01001deepkoala

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