Gene detail

Detailed information of HOLI03627.G26967 in Hydra oligactis

Genomic Location: HOLI03627:8149...56323
NR annotation: XP_047137957.1, C-1-tetrahydrofolate synthase, cytoplasmic-like [Hydra vulgaris]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
P11586	C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4
Q5R8P0	C-1-tetrahydrofolate synthase, cytoplasmic OS=Pongo abelii OX=9601 GN=MTHFD1 PE=2 SV=3
Q3V3R1	Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Mus musculus OX=10090 GN=Mthfd1l PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01268	FTHFS	Formate--tetrahydrofolate ligase	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000559	Family	Formate-tetrahydrofolate ligase, FTHFS	Interproscan
IPR027417	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR020628	Conserved_site	Formate-tetrahydrofolate ligase, FTHFS, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
-	-	-

Gene Ontology

GO terms	Category	Description	Source
GO:0004329	Molecular Function	formate-tetrahydrofolate ligase activity	Interproscan
GO:0005524	Molecular Function	ATP binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00288	MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase	EC:1.5.1.5 EC:3.5.4.9 EC:6.3.4.3	Exosome	ko04147	deepkoala