Genomic Location: HiC_scaffold_2:1399946...1401217
NR annotation: MBQ4875409.1, bifunctional folylpolyglutamate synthase/dihydrofolate synthase [Rickettsiaceae bacterium H1]
| CDS | |||||
| HSymV2.0_g02.02682_t1 | |||||
| Transcript |
| HSymV2.0_g02.02682_t1 |
| Protein |
| HSymV2.0_g02.02682_t1 |
| Uniprot term | Description |
|---|---|
| Q05865 | Dihydrofolate synthase/folylpolyglutamate synthase OS=Bacillus subtilis (strain 168) OX=224308 GN=folC PE=3 SV=2 |
| P15925 | Folylpolyglutamate synthase OS=Lacticaseibacillus casei OX=1582 GN=fpgS PE=1 SV=1 |
| P08192 | Dihydrofolate synthase/folylpolyglutamate synthase OS=Escherichia coli (strain K12) OX=83333 GN=folC PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08245 | Mur_ligase_M | Mur ligase middle domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013221 | Domain | Mur ligase, central | Interproscan |
| IPR001645 | Family | Folylpolyglutamate synthetase | Interproscan |
| IPR036615 | Homologous_superfamily | Mur ligase, C-terminal domain superfamily | Interproscan |
| IPR036565 | Homologous_superfamily | Mur-like, catalytic domain superfamily | Interproscan |
| IPR018109 | Conserved_site | Folylpolyglutamate synthetase, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11136 | FOLYLPOLYGLUTAMATE SYNTHASE-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0009058 | Biological Process | biosynthetic process | Interproscan |
| GO:0016881 | Molecular Function | acid-amino acid ligase activity | Interproscan |
| GO:0004326 | Molecular Function | tetrahydrofolylpolyglutamate synthase activity | Interproscan |
| GO:0009396 | Biological Process | folic acid-containing compound biosynthetic process | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0008841 | Molecular Function | dihydrofolate synthase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11754 | folC; dihydrofolate synthase / folylpolyglutamate synthase | EC:6.3.2.12 EC:6.3.2.17 | Folate biosynthesis | ko00790 | deepkoala |