Gene detail

Detailed information of HSymV2.0_g08.13296_t1 in Hydractinia symbiolongicarpus

Genomic Location: HiC_scaffold_8:7609899...7611003
NR annotation: XP_002156125.3, metalloproteinase inhibitor 3 [Hydra vulgaris]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q9TUL9	Metalloproteinase inhibitor 3 OS=Equus caballus OX=9796 GN=TIMP3 PE=2 SV=1
P35625	Metalloproteinase inhibitor 3 OS=Homo sapiens OX=9606 GN=TIMP3 PE=1 SV=2
P61269	Metalloproteinase inhibitor 3 OS=Macaca fascicularis OX=9541 GN=TIMP3 PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00965	TIMP	Tissue inhibitor of metalloproteinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008993	Homologous_superfamily	Tissue inhibitor of metalloproteinases-like, OB-fold	Interproscan
IPR027465	Homologous_superfamily	Proteinase inhibitor I35b (TIMP), C-terminal	Interproscan
IPR001820	Family	Protease inhibitor I35 (TIMP)	Interproscan
IPR001134	Domain	Netrin domain	Interproscan
IPR030490	Conserved_site	Tissue inhibitor of metalloproteinase, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11844	METALLOPROTEASE INHIBITOR	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0008191	Molecular Function	metalloendopeptidase inhibitor activity	Interproscan
GO:0005515	Molecular Function	protein binding	Interproscan
GO:0002020	Molecular Function	protease binding	Interproscan
GO:0005615	Cellular Component	extracellular space	Interproscan
GO:0010033	Biological Process	obsolete response to organic substance	Interproscan
GO:0010951	Biological Process	negative regulation of endopeptidase activity	Interproscan
GO:0031012	Cellular Component	extracellular matrix	Interproscan
GO:0051045	Biological Process	negative regulation of membrane protein ectodomain proteolysis	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K16866	TIMP3; metalloproteinase inhibitor 3	-	Peptidases and inhibitors	ko01002	deepkoala