Genomic Location: HiC_scaffold_10:12369159...12394378
NR annotation: MBZ3888731.1, Caspase-8 [Sciurus carolinensis]
| CDS | ||||
| HSymV2.0_g10.18231_t1 | ||||
| Transcript |
| HSymV2.0_g10.18231_t1 |
| Protein |
| HSymV2.0_g10.18231_t1 |
| Uniprot term | Description |
|---|---|
| Q14790 | Caspase-8 OS=Homo sapiens OX=9606 GN=CASP8 PE=1 SV=1 |
| Q9JHX4 | Caspase-8 OS=Rattus norvegicus OX=10116 GN=Casp8 PE=1 SV=1 |
| O89110 | Caspase-8 OS=Mus musculus OX=10090 GN=Casp8 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01335 | DED | Death effector domain | Domain | Interproscan |
| PF02585 | PIG-L | GlcNAc-PI de-N-acetylase | Family | Interproscan |
| PF00656 | Peptidase_C14 | Caspase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR051290 | Family | CASP8 and FADD-like apoptosis regulator | Interproscan |
| IPR011029 | Homologous_superfamily | Death-like domain superfamily | Interproscan |
| IPR001309 | Domain | Peptidase C14, p20 domain | Interproscan |
| IPR015917 | Domain | Peptidase C14A, caspase catalytic domain | Interproscan |
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR024078 | Homologous_superfamily | Putative deacetylase LmbE-like domain superfamily | Interproscan |
| IPR001875 | Domain | Death effector domain | Interproscan |
| IPR033139 | Active_site | Peptidase family C14A, cysteine active site | Interproscan |
| IPR016129 | Active_site | Peptidase family C14A, His active site | Interproscan |
| IPR029030 | Homologous_superfamily | Caspase-like domain superfamily | Interproscan |
| IPR002138 | Domain | Peptidase C14, caspase non-catalytic subunit p10 | Interproscan |
| IPR003737 | Family | N-acetylglucosaminyl phosphatidylinositol deacetylase-related | Interproscan |
| IPR011600 | Domain | Peptidase C14, caspase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR48169 | DED DOMAIN-CONTAINING PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004197 | Molecular Function | cysteine-type endopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0008234 | Molecular Function | cysteine-type peptidase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0042981 | Biological Process | regulation of apoptotic process | Interproscan |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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