Gene detail

Detailed information of KAJ7337747.1 in Desmophyllum pertusum

Genomic Location: MU827780.1:486118...503784
NR annotation: KAJ7337747.1, Disintegrin and metalloproteinase domain-containing protein 17 [Desmophyllum pertusum]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

Protein

Uniprot

Uniprot term	Description
P78536	Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ADAM17 PE=1 SV=1
Q9Z1K9	Disintegrin and metalloproteinase domain-containing protein 17 OS=Rattus norvegicus OX=10116 GN=Adam17 PE=1 SV=1
Q9Z0F8	Disintegrin and metalloproteinase domain-containing protein 17 OS=Mus musculus OX=10090 GN=Adam17 PE=1 SV=3

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF16698	ADAM17_MPD	Membrane-proximal domain, switch, for ADAM17	Domain	Interproscan
PF13574	Reprolysin_2	Metallo-peptidase family M12B Reprolysin-like	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036436	Homologous_superfamily	Disintegrin domain superfamily	Interproscan
IPR032029	Domain	ADAM17, membrane-proximal domain	Interproscan
IPR001762	Domain	Disintegrin domain	Interproscan
IPR024079	Homologous_superfamily	Metallopeptidase, catalytic domain superfamily	Interproscan
IPR051489	Family	Disintegrin and Metalloproteinase Domain-Containing	Interproscan
IPR001590	Domain	Peptidase M12B, ADAM/reprolysin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45702	ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0008237	Molecular Function	metallopeptidase activity	Interproscan
GO:0004222	Molecular Function	metalloendopeptidase activity	Interproscan
GO:0005886	Cellular Component	plasma membrane	Interproscan
GO:0006509	Biological Process	membrane protein ectodomain proteolysis	Interproscan
GO:0007219	Biological Process	Notch signaling pathway	Interproscan
GO:0006508	Biological Process	proteolysis	Interproscan