Genomic Location: MU825396.1:6336728...6455847
NR annotation: KAJ7394677.1, 5'-3' exoribonuclease 1 [Desmophyllum pertusum]
Species Desmophyllum pertusum · all data for this species · gene families
| CDS |
| KAJ7394677.1 |
| Protein |
| KAJ7394677.1 |
| UniProt accession | Description |
|---|---|
| Q8IZH2 | 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 |
| P97789 | 5'-3' exoribonuclease 1 OS=Mus musculus OX=10090 GN=Xrn1 PE=1 SV=1 |
| P40383 | 5'-3' exoribonuclease 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=exo2 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001137 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF17846 all species → | XRN_M | Xrn1 helical domain | Domain | Interproscan |
| PF18332 all species → | XRN1_D1 | Exoribonuclease Xrn1 D1 domain | Domain | Interproscan |
| PF03159 all species → | XRN_N | XRN 5'-3' exonuclease N-terminus | Family | Interproscan |
| PF18129 all species → | SH3_12 | Xrn1 SH3-like domain | Domain | Interproscan |
| PF18334 all species → | XRN1_D2_D3 | Exoribonuclease Xrn1 D2/D3 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR016494 all species → | Family | 5'-3' exoribonuclease 1 | Interproscan |
| IPR047007 all species → | Homologous_superfamily | 5'-3' exoribonuclease 1, D1 domain superfamily | Interproscan |
| IPR047008 all species → | Homologous_superfamily | 5'-3' exoribonuclease 1, SH3-like domain superfamily | Interproscan |
| IPR041412 all species → | Domain | Xrn1, helical domain | Interproscan |
| IPR040992 all species → | Domain | 5'-3' exoribonuclease 1, D1 domain | Interproscan |
| IPR004859 all species → | Domain | Xrn1, N-terminal | Interproscan |
| IPR041385 all species → | Domain | 5'-3' exoribonuclease 1, SH3-like domain | Interproscan |
| IPR027073 all species → | Family | 5'-3' exoribonuclease | Interproscan |
| IPR041106 all species → | Domain | Exoribonuclease Xrn1, D2/D3 domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12341 all species → | 5'->3' EXORIBONUCLEASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000956 all species → | Biological Process | nuclear-transcribed mRNA catabolic process | Interproscan |
| GO:0008409 all species → | Molecular Function | 5'-3' exonuclease activity | Interproscan |
| GO:0003676 all species → | Molecular Function | nucleic acid binding | Interproscan |
| GO:0004527 all species → | Molecular Function | exonuclease activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K12618 | XRN1, SEP1, KEM1; 5'-3' exoribonuclease 1 | EC:3.1.13.- | Chromosome and associated proteins | ko03036 | deepkoala |
Genes whose expression across the transcriptome samples of Desmophyllum pertusum tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.
Whether this gene can be visualised in the single-cell atlases of Desmophyllum pertusum, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |