Gene detail

Detailed information of KAK2564022.1 in Acropora cervicornis

Genomic Location: JARQWQ010000023.1:631092...644457
NR annotation: XP_029202779.2, hepatocyte growth factor-regulated tyrosine kinase substrate-like isoform X1 [Acropora millepora]

Gene Structure

More details in Jbrowse

Sequence

CDS

KAK2564022.1

ATGCTGCAGTATGTTTGCAATCAAGTTGATGGGGAGAAAAACTTGTCCAAAATTGTCAAATCTATCAACATTCTTTTGGCTGTTGAATGGGGGAGACAAGCCGGGAATGATGCCTACCAAAGCAATATCATGAAGTGCTGTCAGAGTACTGGTTTGTATCTAGGTGATGAATCCAGCCCTGAACCAGTGAAAGAGCAGATTCTCAGTATGATCCAGACTTGGTCAATAGCCTTTCGCAAAGAGCCAAAATACAAAATTGTTCAGGACACCTTTAATCTCATGAGAATGGAAGGATACAAATTTCCTTCAGTGAATGAATCAAGTGATGCTTTGTTTACAGCAGAAACAGCTCCAGAGTGGGCAGAGGGGGATGTTTGTCACATGTGCAGAGTTAAGTTTTCAACCTTTCAAAGACAGCACCACTGCAGGAACTGTGGTCAAGTATTTTGTCAGAAGTGTTCCTCAAGAGTGTCCATAATTCCACAATATGGTATAGAAAGGGAAGTAAGGGTCTGTGATCCCTGCTTCTATAAACTCAATCCCTCGGCTAGCAAAAGTGAAGAAGGCTCAAAGAAGTCTGAAAGTGCATCATCTGACAAAGATTTGCCTCCAGAATACCTCAACAGTCCACTGAGTAGAGAATCTCAGACACCTGCTAAGAAAACTGCAAAAGAAATTCAAGAGGAAGAGGAAGAGGAATTACAGTTGGCACTGGCGTTGTCACTGTCACAAGAAGAGGCTGCCAAAGATAGTCGACAACGTCCAAGTACCAAGTCAAATGAAGCCAGAGAACCATCATACAGCTCCTACAGGCAGACCAGCAATTTGTATTCGTCTCCTATGGATGATGTAGTAACTGACTCAGCCAGTGTGGACCCTGAGCTTGCACGATACCTGAATCGCTCGTATTGGGAGGAGAGGAACGAGAGACAGACATCAAAAATTAGGTCCAGTGTTCCTGCAAGCGTGCAAGGGCAGAGAGAAGAACTCAATGAATATTCAGATAAGAAAATTGTAAGTGGAATCTTGAAAGGAAAAAGGAAGGGGAAGAAAATGACAAGCGACAACTTTCACTCGACTACGGTCAATAACATTCTCTTGTTAAAGGCAATTAACCTGTATCTCCTTCCTCTTAAACGCTCCATAAAAGATGACCACGAAACCTCTGAAACAACGTCCGAAGTGTCGGATGCTATGGTGAAGAACTTCCACAGCAGCGTTGAAATGTTGCTGGAACGAATGCAGAAAGTGTCTGGCCAGGGAAAACACATTGCCATGGACGCTACTGTGCAGTCTTTGTTTCAAACTGTCAGCGCCATGCATCCTCAGATTCTCAGATTCATTGAACAACTAGAAGAAGAGACAGCCAAATATGAAGCCCTACAAGTTAAAGTGGGTCTTGTCCGTGAGGCGCGCTCGTCTTTGGATGAAATGCGAGAACAACATCGAGAAAAAGTGCGACAACAAGAACTGGAACAGGATATGCTGAGGCGTATGCAAATAGAACAGAAACTAGAGCTGATGCGTCAGCAGAAAGCCGAGTACCTGGCCTATCAACAAAGATTACAAGCGGAGCGACAAACAGCCATAGAACAACAACAACAACAAAGAACTCAATACCAGAGACCCATGCAGATGCAACAGTACCAGTACCCCACTGCAGGAGATTCCAGCCCTTATTCGTCCTTGAATTATTTACCTGTAACTGTGGCCAGTTCACAGCCTTATACCTCCCAGAATACATCTGCTGCTTACACATCTGCTGTACCACAGAGTTACCAGGTGCCTGATGCTCCCCTGCCCTCGCAATATCCTACTCATTCTCCTCCAAGTGCCTATTCACAGGCTTATCGTTCTGAGTTAATGCCGTATAGGAACGATGCACCAACATCTCAAGCAGAGCCCCAGCCTCAGCCGAGTTCCTTGGAGTACCAACCTCCCATGTATGCTTCTCAGGTTCAAGCTGACCAGGGGCCAGCTTCACTTCAGTCTTATAGTCTTGGAGGGCCGTCTCCAGTCCCTACTGCTCCAGCGCAAGTTATAGCTCAAGCACCACCCCCTCAGTATGCTCAGGTCACTTCTCAGCAACCAAGCTCTCAACAGCCGTATGGAGGACAACTGGGAAATCAACAGCCACCACCACAAACCACACCACTGAATCAGTACCCTGTGGTAATGCCCCCCTCTGTCACAGGGCAACCAAAGATGAATCAGATACCACCATCTCAGAGCCAACCGCAGTTTTCACGACAAACACAGTTGGCTAATACAGGGCCACATCTACCTGAGGCCACTCCTTCACAGTTAACCAACCCTCCACAAGCTCAGTTTTTACCGGAAGGGGTTGCGTCACAGTATACCCATCCAGCATCACAGGTTACACAACCCAAACCCCAGACATTTCAGTCTCCCGAGATCAATGGTTTTCCTTCTGTAGATGCCTCTCAGATCCCACCACAAATGTTTTCATCTGGCTCGTTACAGCCACAGCTAAACATGGGTCAGCCCTCATTTCAACAAGGACACCTAATACAACAAGGACAACCAGGAGGTAATTCTCTCCAAGGGTCTTCAGCACAGCAAGGACCACCAATACAGCAGGCACCTCCTATGCAACAGGTTTATGAACCGCAGCAACAACAGCCCCAACAATTTGGACCTCAACAAGGCTACCAACCTGGTCCAGGCCAAGGTCCACCTGGCCAACAGCAGCCACCACCACAGTACTATGGATCAGCACTACCCCCTCAGCAGTCAAACCAAGCCCCGCAGAGACAATTGTCTGACTTAGAACTGATTTCATTTGACTAA

Transcript

Protein

Uniprot

Gene family

Uniprot term	Description
O14964	Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1
Q0V8S0	Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Bos taurus OX=9913 GN=HGS PE=2 SV=1
Q99LI8	Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Mus musculus OX=10090 GN=Hgs PE=1 SV=2

Gene family	Subfamily
Ubiquitin Family	UBD\|Alpha-Helix\|VHS

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF12210	Hrs_helical	Hepatocyte growth factor-regulated tyrosine kinase substrate	Domain	Interproscan
PF01363	FYVE	FYVE zinc finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR017073	Family	Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27	Interproscan
IPR000306	Domain	FYVE zinc finger	Interproscan
IPR003903	Conserved_site	Ubiquitin interacting motif	Interproscan
IPR024641	Domain	Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain	Interproscan
IPR013083	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan
IPR008942	Homologous_superfamily	ENTH/VHS	Interproscan
IPR017455	Domain	Zinc finger, FYVE-related	Interproscan
IPR002014	Domain	VHS domain	Interproscan
IPR011011	Homologous_superfamily	Zinc finger, FYVE/PHD-type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46275	HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005769	Cellular Component	early endosome	Interproscan
GO:0031623	Biological Process	receptor internalization	Interproscan
GO:0032456	Biological Process	endocytic recycling	Interproscan
GO:0043130	Molecular Function	ubiquitin binding	Interproscan
GO:0046872	Molecular Function	metal ion binding	Interproscan
GO:0035091	Molecular Function	phosphatidylinositol binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K12182	HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate	-	Membrane trafficking	ko04131	deepkoala